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This paper is intended to give an overview of the current work of the International Commission on Radiological Protection (ICRP) within the field of medicine and healthcare. The paper focuses on the work carried out in Committee 3. Some views expressed at the ICRP Seminar in Bethesda, USA in October 2011 will also be discussed. Similar and complementary work by other organisatons will also be brie

Background: Potato late blight caused by the oomycete pathogen Phytophthora infestans can lead to immense yield loss. We investigated the transcriptome of Solanum tubersoum (cv. Desiree) and characterized the secretome by quantitative proteomics after foliar application of the protective agent phosphite. We also studied the distribution of phosphite in planta after application and tested transgeni

Carbon paste electrodes modified with a phenoxazine derivative, Meldola blue, and a phenothiazine derivative, methylene green, both strongly adsorbed on a synthetic zeolite were investigated using either glassy carbon powder (Sigradur K, SK) or single-walled carbon nanotubes (SWCNT) as conductive electrode material. In the case of SWCNT based electrodes, the formal potential of both mediators was

Environmental exposures to endocrine disrupting chemicals have been suggested as a risk factor for male genital abnormalities such as hypospadias. The aim of this case-control study was to investigate the association between fetal exposure to persistent organochlorine pollutants (POP) and the risk for hypospadias.

We examined whether zinc transporter-8 autoantibodies (ZnT8A; arginine ZnT8-RA, tryptophan ZnT8-WA, and glutamine ZnT8-QA variants) differed between immigrant and Swedish patients due to different polymorphisms of SLC30A8, HLA-DQ, or both. Newly diagnosed autoimmune (≥1 islet autoantibody) T1D type 1 diabetic patients (n = 2,964, <18 years, 55% male) were ascertained in the Better Diabetes Diagnos

Objectives. To establish the gender difference amongst newly diagnosed type 1 diabetic patients aged 15-34 years, considering age at diagnosis, temporal trend and seasonal variation at time of diagnosis. Study design. A population-based prospective study with a mean annual population at risk of 2.3 million. Setting. All departments of medicine, endocrinology and paediatrics and primary health care

Dynamic chromatin structure is a fundamental property of gene transcriptional regulation, and has emerged as a critical modulator of physiological processes during cellular differentiation and development. Analysis of chromatin structure using molecular biology and biochemical assays in rare somatic stem and progenitor cells is key for understanding these processes but poses a great challenge beca

Psychiatric and metabolic features appear several years before motor disturbances in the neurodegenerative Huntington's disease (HD), caused by an expanded CAG repeat in the huntingtin (HTT) gene. Although the mechanisms leading to these aspects are unknown, dysfunction in the hypothalamus, a brain region controlling emotion and metabolism, has been suggested. A direct link between the expression

Pathogenic microbes acquire the human plasma protein plasminogen to their surface. In this article, we characterize binding of this important coagulation regulator to the respiratory pathogen nontypeable Haemophilus influenzae and identify the Haemophilus surface protein E (PE) as a new plasminogen-binding protein. Plasminogen binds dose dependently to intact bacteria and to purified PE. The plasm

Structural and electronic properties of TiO2 nanoparticles sensitized with a set of RuII(tpy)(2) based dyes have been investigated using density functional theory (DFT) calculations combined with time-dependent (TD) DFT calculations. The effects of carboxylic and phosphonic acid anchor groups, as well as a phenylene spacer group, on the optical properties of the dyes and the electronic interaction

This paper contains a study of the Nobel Peace Prize winner Liu Xiaobo’s texts on the Iraq war, and the implications of the problem representation encompassed in his view on the war. By use of the “What’s the problem represented to be?”- approach by Carol Bacchi, I have found that the problem representation in Liu Xiaobo’s texts on the Iraq war is “lack of democracy and freedom”. Because of the pr

As foreign aid money is continually spent in developing countries, it is incumbent that international aid organizations work towards improving the effectiveness of their projects. In the setting and context of disaster risk reduction and disaster recovery projects, this thesis aims to understand how foreign aid organizations can make Honduran communities less dependent on foreign aid through speci

In The Girl with the Dragon Tattoo, Stieg Larsson depicts a fiery, independent and highly sexual protagonist in the character of Lisbeth Salander. While many readers fail to notice the subtle reference to Lisbeth’s natural red hair, this quality, along with Larsson’s admittance that his inspiration originated from Astrid Lindgren’s Pippi Longstocking, situates Lisbeth in a long tradition of redhea

Gränser mellan vegetationszoner fascinerar genom att på ett tydligt sätt påminna oss om sambanden som finns mellan det som lever och dess miljö. En av de mest påtagliga gränserna är den alpina trädgränsen, där fjällbjörkskogen gradvis övergår till kalfjäll. Den karga miljön som utgör kalfjället är starkt kopplat med temperatur och klimatförändringens ökade temperatur har medfört förändringar i träAerial photo interpretation shows a recent densification of trees has been occurring between 1960 and 2009 in the mountain birch (Betula pubescens ssp. czerepanovii) forest of the treeline ecotone in northern Swedish mountains. The correlation between treeline position and annual temperature is commonly accepted and advancing treelines are considered to be a useful indicator for monitoring climate

This Letter presents a measurement of W(+/-)Z production in 1.02 fb(-1) of pp collision data at root s = 7 TeV collected by the ATLAS experiment in 2011. Doubly leptonic decay events are selected with electrons, muons and missing transverse momentum in the final state. In total 71 candidates are observed, with a background expectation of 12.1 +/- 1.4(stat.)(-2.0)(+4.1)(syst.) events. The total cro

BACKGROUND: Surveys are a common way to measure annoyance due to road traffic noise, but the method has some draw-backs. Survey context, question wording and answer alternatives could affect participation and answers and could have implications when comparing studies and/or performing pooled analyses. The aim of this study was to investigate the difference in annoyance reporting due to road traffi

The ever increasing data rates in wireless communication require analog to digital converters (ADCs) with greater requirements on speed and accuracy, while being power efficient to prolong battery life. This dissertation contains an introduction to the field and five papers that focus on the continuous-time (CT) Delta-Sigma modulator (DSM) as ADC. Paper I analyses the performance degradation of d