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The early Cambrian Sirius Passet fauna of northernmost Greenland (Cambrian Series 2, Stage 3) contains exceptionally preserved soft tissues that provide an important window to early animal evolution, while the surrounding sediment holds critical data on the palaeodepositional water-column chemistry. The present study combines palaeontological data with a multiproxy geochemical approach based on sa
The Biology/Disease-driven (B/D) working groups of the Human Proteome Project are alliances of research groups aimed at developing or improving proteomic tools to support specific biological or disease-related research areas. Here, we describe the activities and progress to date of the B/D working group focused on protein aggregation diseases (PADs). PADs are characterized by the intra- or extrace
Mycobacterium tuberculosis, the causative agent of human tuberculosis (TB), has surpassed HIV/AIDS as the leading cause of death from a single infectious agent. The increasing occurrence of drug-resistant strains has become a major challenge for health care systems and, in some cases, has rendered TB untreatable. However, the development of new TB drugs has been plagued with high failure rates and
Purpose: To investigate the main concerns associated with being a parent of a child with cataract and how the parents deal with these concerns. Design and method: Twenty-three parents; 6 mothers, 5 fathers and 6 couples with a child with cataract were included in this study. The parents included some with a personal experience of cataract and some without. Data was collected through 17 in-depth in
Purpose: Chronic wounds are a major public health challenge, but little is known about the true burden with studies reporting different estimates because of disparities in study designs and measurement methods. This hampers efficient resource allocation, planning, and improvement of wound care. Methods: Our study aimed to pool prevalence estimates from a global perspective by systematically carryi
METHODS: Retrospective analysis of prospectively collected data 2010-2014 from the Swedish national dementia registry (SveDem) and the Swedish national stroke registry (Riksstroke). Patients with dementia who suffered an acute ischemic stroke (AIS) (n = 1,356) were compared with matched non-dementia AIS patients (n = 6,755). Outcomes included length of stay in a stroke unit, total length of hospit
Evidence suggests that research benefits from diversity, yet science is concentrated to a small group of countries. Diversity in physical therapy research has so far not been studied thoroughly, and this is the first study to map physical therapy research geographically. The objective was to study the frequency and methodological quality of physical therapy-related randomized controlled trials (RC
We have performed a systematic computational study of the relative energies of possible protonation states of the FeMo cluster in nitrogenase in the E0-E4 states, i.e., the resting state and states with 1-4 electrons and protons added but before N2 binds. We use the combined quantum mechanics and molecular mechanics (QM/MM) approach, including the complete solvated heterotetrameric enzyme in the c
The campus of the National Metsovian Polytechnic in central Athens has been a signi cant cornerstone in the socio-political landscape of the city. Within the history of modern Greece, Polytechneio is regarded as a symbol of resistance against the Greek military dictatorship (junta) in 1973. In March 2015 and during times of austerity politics, the west façades of the Polytechneio were covered by a
We will present results from a recently completed research project financed by BFUF (the R&D Fund of the Swedish Tourism & Hospitality Industry). We have explored German tourists and how they search for tourist information at home and while travelling in Sweden. The overall aim was to understand how tourists’ information search behaviour affects the choice of attractions. The
This study is an attempt to empirically determine and analyse the factors that significantly influence the perceptions of and vulnerability to an earthquake disaster that struck a community located in the Hazaribagh area of Dhaka South City, Bangladesh. The empirical results reveal a significant relationship between a number of sociodemographic factors and the community's perceptions of and level
Correlations of two flow harmonics vn and vm via three- and four-particle cumulants are measured in 13 TeV pp, 5.02 TeV p+Pb, and 2.76 TeV peripheral Pb+Pb collisions with the ATLAS detector at the LHC. The goal is to understand the multi-particle nature of the long-range collective phenomenon in these collision systems. The large non-flow background from dijet production present in the standard c
Context. The Gaia-ESO Public Spectroscopic Survey using FLAMES at the VLT has obtained high-resolution UVES spectra for a large number of giant stars, allowing a determination of the abundances of the key chemical elements carbon and nitrogen at their surface. The surface abundances of these chemical species are known to change in stars during their evolution on the red giant branch (RGB) after th
Objective: (1) To estimate the life-time genetic contribution for knee osteoarthritis (OA) surgery and (2) to explore any differences in the genetic contribution across age, sex and body mass index (BMI). Methods: We studied the sex-specific genetic contribution to knee OA surgery in a prospective cohort study of 62,490 twins aged 35 years or older with a follow-up period of up to 47 years (10,092
Objective: To identify differences in the management and outcome of patients with central nervous system metastases from epithelial ovarian cancer. Methods: The clinical and pathologic characteristics, treatment, and outcome of 23 patients with brain metastases from epithelial ovarian cancer who were treated during 1982-1994 were compared with those of 20 patients treated during 1995-2010 at the s
The response of the ATLAS detector to large-radius jets is measured in situ using 36.2 fb - 1 of s=13 TeV proton–proton collisions provided by the LHC and recorded by the ATLAS experiment during 2015 and 2016. The jet energy scale is measured in events where the jet recoils against a reference object, which can be either a calibrated photon, a reconstructed Z boson, or a system of well-measured s
Sidewall proximity, characterized by the gap distance (G) between border pin-fin column and sidewall in a pin-finned microchannel with in-line arrangement, plays a significant role on pressure drop and heat transfer characteristics. To better understand the thermal performance and explore the underlying mechanisms, a comprehensive comparison is numerically developed among three representative micr
This article analyses discourses about self-supporting women in Swedish women’s magazines in the 1920s, after the attainment of legal equality in marriage and the acquisition of the right to vote. The self-supporting middle class woman was a controversial figure in this context. On the one hand symbolizing freedom and independence, she was on the other hand ridiculed and labelled mannish and unatt
