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Electrophysiological and pharmacological properties of neurons within solid basal forebrain transplants were studied in adult rats anesthetized with urethane. No specific topography of the neurons recorded was observed within the graft. The mean spontaneous activity of the grafted neurons (GNs) was relatively low (4.9 impulses/s) but not unlike that of other central neurons in situ. A large propor
The Chinese-led Asian Infrastructure Investment Bank (AIIB) started operation in January 2016 in the context of severe criticism from the U.S. government and transnational civil society organizations, but with the support from major Asian and European states. The establishment of this new global governance institution (GGI) raises intriguing questions concerning legitimacy and (de)legitimation. Wh
We review our recent studies of excited state structures and dynamics of chemical and biological systems with pico- and femtosecond X-ray absorption spectroscopy in the liquid phase.
This paper presents a qualitative questionnaire study of brand-specific visual product design in the automotive sector. The purpose of the study was to explore the visual product experience of automobile design as perceived by the general public and to analyse those experiences using an emerging framework for visual product experience; VPE. In the study; respondents were asked to assess the design
While scholars commonly assume that Global Governance Institutions (GGIs) need legitimacy to perform effectively, there are few systematic empirical studies assessing the consequences of legitimacy (or the lack thereof) for the functioning of GGIs. Inspired by the new institutionalism in organization theory, which predicts that more legitimate organizations will get more resources than illegitimat
The effect of alcohol intake on varicose veins (VV) has not been determined by its consumption level. The aim of this study was to investigate the association between alcohol intake and VV in an elderly general population. Using a cross-sectional approach, the Shimane CoHRE Study data, comprising a total of 1060 participants, were analyzed. By multivariate regression analysis adjusted with basic c
Background and objectives: Despite global warming, the climate in Northern Europe is generally cold, and the large number of deaths due to non-optimal temperatures is likely due to cold temperatures. The aim of the current study is to investigate the association between cold temperatures and all-cause mortality, as well as cause-specific mortality, in Tallinn and Riga in North-Eastern Europe. Mate
BACKGROUND: There is growing evidence for a negative impact of traffic-related air pollution on risk of dementia. However, the contribution of noise exposure to this association has been rarely examined.OBJECTIVE: We aimed to investigate the individual and combined effect of noise and air pollution on risk of dementia.METHODS: Data on dementia incidence over a 15 year period was obtained from the
The article is devoted to an analysis of legal acts of the Republic of Uzbekistan on counteraction against corruption. The article provides the classification and review of the anti-corruption legislation of Uzbekistan. The article also deliberates about the measures taken by Uzbekistan to implement relevant international legal standards into the national legal system. It considers not only the le
Public transport is an important part of the transition to a more sustainable future. The increasingly market-oriented public transport companies today market themselves with a wealth of messages in multiple channels such as direct mail, websites and apps. This communication is part of the influence that the (potential) traveler is exposed to, yet little research and testing is carried out in orde
Developing a place into ‘a good place to live’ for people of all ages is a prioritized issue in many municipalities in Sweden, as well as around the world. But what do we really mean by ‘a good place to live’? How do the residents themselves comprehend and perceive ‘a good place to live’? And how do municipalities view their place and what they offer to their residents? This thesis explores how ‘a
Neuropeptide Y (NPY) is a powerful vasoconstrictor in vivo but is usually much less active on isolated blood vessels. The contractile effect of NPY was examined in the isolated rat femoral artery exposed to various degrees of vasoconstriction. The effects of NPY on the relaxation induced by vasodilator agents was also studied. NPY (< or = 1 microM) had no contractile effect. In vessels pretreated
MLL rearrangements are translocation mutations that cause both acute lymphoblastic leukemia and acute myeloid leukemia (AML). These translocations can occur as sole clonal driver mutations in infant leukemias, suggesting that fetal or neonatal hematopoietic progenitors may be exquisitely sensitive to transformation by MLL fusion proteins. To test this possibility, we used transgenic mice to induce
Blastenia is a widely distributed lichen genus in Teloschistaceae. We reconstructed its phylogeny in order to test species delimitation and to find evolutionary drivers forming recent Blastenia diversity. The origin of Blastenia is dated to the early Tertiary period, but later diversification events are distinctly younger. We recognized 24 species (plus 2 subspecies) within 6 infrageneric groups.
The β-cell function, total islet volume, and number were studied in 1- to 18-month-old mice, together with the extractable pancreatic insulin and glucagon. The β-cell function, determined as the total amount of insulin released in response to glucose from the in vitro perfused pancreas showed an agerelated increase, without any differences in the kinetics of insulin secretion between young and old
