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Purpose: Bladder outlet obstruction leads to bladder enlargement and subsequent decreases in contractile function in vivo and in vitro. We determined whether there were regional differences in bladder wall properties and in vitro contractile responses after 2 weeks of bladder outlet obstruction. Materials and Methods: Male rabbits underwent cystometry. The bladder was then filled to 40 ml. and the
Abstract is not available
The aim of this study was to investigate a new extracorporeal immunoadsorption method to improve tumor-to-normal tissue ratios in radioimmunoimaging (RII) and radioimmunotherapy (RIT). We have developed and investigated a general method using biotinylated antibodies and an agarose-avidin column for extracorporeal immunoadsorption. The studies were made in an animal model and extracorporeal immunoa
The reaction pathways in the ammoxidation of propene and of propane over an Sb-V-oxide catalyst were studied by analyzing the modes of transient responses of reactants and products resulting from step changes from inert gas to reactant feed. The pathway from propane to acrylonitrile begins with the oxidative dehydrogenation of propane to form propene. After readsorption, the propene is then transf
PURPOSE: Vascular disease is differentiated throughout the vascular regions, with central arteries more prone to dilation and with peripheral arteries more prone to occlusive disease. In this study we investigated the diameter and compliance in the common carotid artery and abdominal aorta in healthy males at varying ages to assess potential differences in the aging process. METHODS: An ultrasound
Although a negative trade-off between current reproductive effort and future reproductive output has for long been hypothesized and in some cases empirically shown, no mechanism with the potential to mediate such a reproductive cost from one season to another has been demonstrated. Here we suggest such a mechanism: the time and/or energy constraints during moult. We manipulated current reproductio
Spring migration of arctic breeding birds, mainly waders and Dark-bellied Brent Geese Branta bernicla, was followed by tracking radar in Lund, South Sweden, during 1998-2001 in order to evaluate the capacity of these birds to exploit favourable winds. A total of 888 radar tracks were collected. Here I report on measured flight speeds, flight altitudes and winds and compare these with results from
Popular Abstract in Swedish Solljusets effekter på abiotiska och bakteriella kolflöden i akvatiska system I denna avhandling behandlar jag solljusets effekter på organiskt material. Jag har analyserat hur solljus förändrar olika sorters löst organiskt kol och partikulärt organiskt kol. Vidare har jag utvärderat de indirekta effekterna som förändringar av löst organiskt kol har på bakterier. SlutlIn this Thesis, I studied some of the current aspects of organic matter photochemistry. I analyzed abiotic phototransformations of several types of dissolved (DOM) and particulate organic matter (POM). I also evaluated the effects of phototransformation of several types of DOM on bacteria. Finally, in a field experiment, I analyzed net effects of solar radiation on organic matter decomposition. DO
Guidelines for the treatment of risk factors in diabetes care have been updated recently, due to indisputable results from clinical end-point trials. This study evaluates risk factor control compared with current national and international targets during the period 1996-2003 in Type 2 diabetes (DM2). Patients were registered in primary-care and hospital outpatient clinics using computer software,
Subspecies of Trypanosoma brucei cause severe brain diseases after penetration of the blood-brain barrier. We investigated whether cytokines that modulate inflammatory cell infiltration into the brain also influence T. brucei neuroinvasion. Migration of a rodent pathogenic T. brucei strain from the cerebral blood vessels into the brain parenchyma was impeded in IFN-gamma(-/-), IFN-gamma receptor(-
Calcitonin gene-related peptide and adrenomedullin belong to a structurally related neuropeptide family and are potent vasodilators expressed in the trigeminovascular system. The molecular identity of receptors for these proteins has only recently been elucidated. Central to functional binding of these neuropeptides is the G-protein-coupled receptor, the calcitonin receptor-like receptor (CRLR), W
Modification of the St. John's wort acylphloroglucinol constituent, hyperforin (1), by acylation, alkylation, and oxidation resulted in detrimental effects on the inhibition of the synaptosomal accumulation of serotonin, showing the existence of definite structure-activity relationships in this in vitro test system and highlighting the role of the enolized cyclohexanedione moiety for activity on n
There are an increasing number of genetic and neuropathological observations to suggest that cystatin C, an extracellular protein produced by all nucleated cells, might play a role in the pathophysiology of sporadic Alzheimer's disease (AD). Recent observations indicate that small and large soluble oligomers of the beta-amyloid protein (A beta) impair synaptic plasticity and induce neurotoxicity i
A compilation of available test results relating to the strength of glulam beams with holes is presented. A total of 182 individual tests from 8 different sources are described concerning material, test setup and recorded crack loads and failure loads. A brief description of some available methods for strength analysis of timber is given and specific calculation approaches for the strength of glul
Even before the discovery of X-rays in 1895 attempts were being made to classify the joint destruction that occurs in hemophilic arthropathy. The advent of radiography added impetus to the search for the optimum classification system. Subsequent attempts have included advanced imaging methods, especially magnetic resonance imaging (MRI). Because of its high spatial resolution and ability to Visual
The Furongian (upper Cambrian) Leptoplastus Zone marks a time of critical changes in the evolution of olenid trilobites. This zone, unexposed at Andrarum in Skane, southern Sweden, has been re-excavated and the sequence of faunas and sediments logged in detail. The faunal succession accords with that previously described from borehole cores by Westergard, and the subzones of L. paucisegmentatus, L
