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BACKGROUND: Consistent data on clinical features, treatment modalities and long-term survival in patients with hepatocellular carcinoma (HCC) using nationwide quality registers are lacking. This study aimed to describe treatment patterns and survival outcomes in patients diagnosed with HCC using a national maintained database. METHODS: Characteristics and treatment patterns in patients diagnosed w
3-Phosphoglycerate dehydrogenase (3-PGDH) deficiency is an inborn error of serine biosynthesis. Patients are affected with congenital microcephaly, psychomotor retardation, and intractable seizures. The effects of oral treatment with amino acids were investigated in 2 siblings. L-Serine up to 500 mg/kg/day was not sufficient for seizure control. Addition of glycine 200 mg/kg/day resulted in comple
Ancient remains found in permafrost represent a rare opportunity to study past ecosystems. Here, we present an exceptionally well-preserved ancient bird carcass found in the Siberian permafrost, along with a radiocarbon date and a reconstruction of its complete mitochondrial genome. The carcass was radiocarbon dated to approximately 44-49 ka BP, and was genetically identified as a female horned la
Cardiovascular disease (CVD) is the most common cause of death in industrialized countries. One underlying cause is atherosclerosis, which is a systemic disease characterized by plaques of retained lipids, inflammatory cells, apoptotic cells, calcium and extracellular matrix (ECM) proteins in the arterial wall. The biologic composition of an atherosclerotic plaque determines whether the plaque is
A case‐referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty‐five male STS patients were thereby compared with 220 living and 110 dead population‐based referents. Furthermore, another referent group consisting of 190 patients with anothe
This article focuses on the ways in which women employed in Vietnam’s heavy industry, mitigate and cope with crises at the workplace and in social life. Drawing on ethnographic fieldwork, which I have conducted in the Industrial Zones of northern Vietnam in the international corporations called Xylan and Yate, I examine how women who are working on the floor manage crises entanglements as an unde
This paper deals with the issue of former border railway stations (FBRSs) in Poland in the context of their problematic heritage. Since the creation of those borders coincided with the development of the railway network in the 19th century, the FBRSs, now deprived of their past function, remain scattered throughout the landscape as confusing components of a troubled history in an even more confusi
Importance: Better understanding is needed of the degree to which individuals tolerate Alzheimer disease (AD)-like pathological tau with respect to brain structure (brain resilience) and cognition (cognitive resilience). Objective: To examine the demographic (age, sex, and educational level), genetic (APOE-ϵ4 status), and neuroimaging (white matter hyperintensities and cortical thickness) factors
Aim: The present study describes, through a meta-synthesis, the relationship between patients, informal caregivers and health professionals involved in home care. Background: Today, many people receive help from health care professionals in their homes with the consequence that, for many health care professionals, their working place is the patients' homes. Research that addresses the dynamics in
Rationale and aims: The Quality of Dyadic Relationships is a self-assessment scale used to evaluate various aspects of relationship quality. Psychometric evaluation by the developers of the instrument has led to a nontested amended version. Further psychometric testing is thus warranted, and the aim of this study was to evaluate homogeneity, construct validity (in terms of concurrent, discriminant
The Xiamaling Formation is an exceptionally well-preserved sedimentary succession deposited on a marine passive margin about 1400 million years ago. We used a multi-proxy approach, including iron speciation, trace metal dynamics, and organic geochemistry, to explore the evolution of ocean chemistry through most of the Xiamaling Formation. This evolution is put in the context of the paleogeography
Extracts of different body parts of adult Trichoptera were tested for electrophysiological activity. Extracts of the IVth and Vth abdominal sternites of female Hydropsyche angustipennis, Rhyacophila nubila, and R. fasciata, containing a paired exocrine gland, elicited significant electroan-tennographic responses when tested on conspecific male antennae. The paired gland occurs also in males of all
This research examines the degree to which legislators respond to their districts by analyzing immigration‐related legislative speeches from the Swedish parliament (2005–16). Using a text‐scaling method, we find that the immigration discourse fluctuates between “socioeconomic responsibility” and “cultural difference” poles. We argue that socioeconomic declines and extreme‐right party success serve
