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How is sustainable development translated in higher education institutions (HEIs)? This study examines how sustainable development has been translated within the ‘policy world’ of HEIs, focusing on one research-intensive university in Sweden. Sustainable development, widely introduced into legislation in 2003, required HEIs to develop policies addressing sustainability. At one faculty at the resea
Patients with pulmonary arterial hypertension (PAH) experience long diagnostic delays, high functional class at diagnosis and poor prognosis. We aimed to study the differentiative and predictive value of 90 inflammatory and immunomodulatory related proteins in idiopathic and hereditary PAH (IPAH/HPAH) and systemic sclerosis-associated PAH (SSc-APAH). Cohort 1 comprised patients with SSc-APAH ( n
The article offers a discussion of Sofi Oksanen’s novelPurge, focusing on the book’s strategy of evoking stereotypicalnarratives about Eastern Europe, such as the (postcommunist) fallenwoman and (Russian) return home narratives, as well as relatedintertexts, primarily Lukas Moodysson’s film Lilya 4-ever. I argue thatOksanen constructs the plot around clichés in order to challenge them ina subversi
Darknet framställs ofta som en digital värld präglad av avvikelse och kriminalitet – en plats där ”allt är tillåtet” och som därför anses kräva övervakning och kontroll. Trots detta är kryptoforum fortfarande relativt understuderade. Med utgångspunkt i tre års etnografiskt fältarbete ger denna avhandling nya insikter i de interna dynamikerna i en till stor del dold onlinegemenskap. Genom att kombiThe Darknet is often portrayed as an online realm marked by deviance and criminality – a space where “anything goes” and therefore requires policing. Yet its cryptoforums remain comparatively understudied. Drawing on three years of ethnographic fieldwork, this dissertation provides new insights into the internal dynamics of a largely hidden online community. Combining digital observations with 19
Comparative thinking is a fundamental human drive and a hallmark of contemporary life. For social action, such as the learning and use of additional languages, a target for appraisal (an L2 attribute) is evaluated in relation to a comparison standard (an appraiser's standpoint). An appraiser can be the person themselves, another person, a social group, people in a particular social context, or, in
Several ice-dammed lakes formed between the Younger Dryas moraines and the Tana River valley during the retreat of the Fennoscandian Ice Sheet over northeast Norway. Drainage of these lakes left an indelible scar on the landscape; the Gaccetávži ravine, a feature over 10 km long and up to 120 m deep. Here, we use LiDAR-derived digital terrain models, alongside field investigations and novel remote
Breaking promises might be easier if one faces unexpectedly high costs for keeping them. Inspired by the ‘pledge and review’ mechanisms of the Paris Agreement, we investigate the role of cost uncertainty for both initial non-binding pledges and the subsequent voluntary provision of public goods. Without a pledge review process, we find that cost uncertainty not only leads to rather conservative pl
Monoclonal gammopathy of undetermined significance (MGUS) is a necessary precursor condition to multiple myeloma (MM). Given the role of autophagy in modulating MM risk, we investigated whether genetic variation in autophagy-related genes influences susceptibility to MGUS. We analyzed the association of 34,042 common autophagy-related single nucleotide polymorphisms (SNPs) with MGUS across six ind
BACKGROUND AND OBJECTIVES: Iron deficiency anaemia is common in patients recovering from major surgery and is associated with poorer post-operative outcomes. We designed a randomized controlled trial treating post-operative anaemia with iron therapy to observe the influence on post-operative recovery.MATERIALS AND METHODS: Anaemic patients (haemoglobin [Hb] < 120 g/L for women, Hb < 130 g/L for me
Yersinia pathogenicity is dependent on polarized translocation of effector proteins via the type III secretion system (T3SS). The tip complex situated on the needle structure of the T3SS is required for contact with the eukaryotic host membrane and is to an extent composed of pentameric LcrV. LcrV is a multifunctional protein that also acts as a regulator of the T3SS by virtue of forming a high-af
This work investigates lightweight personalisation of micro-electro-mechanical systems (MEMS)-based wearables using a public padel database as a case study. We compare a centralised CNN model, single-user models and two fine-tuning schemes (full and last-layer) on wrist-worn IMU data from 23 players and 13 stroke classes. Personalised models with data augmentation achieve weighted F1-scores above
We report the discovery of two warm exoplanets orbiting the cool binary system TOI-2267, composed of the M5 (TOI-2267A) and M6 (TOI-2267B) stars, whose angular separation is 0.384 arcsec, corresponding to a projected distance of only about 8 au at 22 pc from the Solar System. To confirm the planetary nature of these objects, we combined photometry from the Transiting Exoplanet Survey Satellite (TE
Digital phantoms are virtual representations of the human body used in medical research to test equipment, train medical professionals and develop or validate algorithms. These models can be created from ‘real-world’ clinical data or from ‘synthetic data’. Phantoms derived from clinical data often serves as ‘ground truth’ reference values anchored in empirical observations. However, there is growi
Ageing in the human brain is a major risk factor for most neurodegenerative diseases. Yet the cell-type-specific molecular changes that contribute to this risk remain poorly understood. This thesis investigates cell-type-specific changes across multiple levels of molecular regulation and their roles in physiological and pathophysiological brain ageing. Using single-nucleus RNA sequencing of postmo
The training of the state-of-the-art Deep Neural Networks (DNNs) consumes massive amounts of energy, while the human brain learns new tasks with remarkable efficiency. Currently, the training of DNNs relies almost exclusively on Backpropagation (BP). However, BP faces criticism due to its biologically implausible nature, underscoring the significant disparity in performance and energy efficiency b
This paper presents the measurement of the isolated prompt photon inclusive production cross section in pp and p–Pb collisions by the ALICE Collaboration at the LHC. The measurement is performed in p–Pb collisions at centre-of-mass energies per nucleon pair of sNN=5.02TeV and 8.16 TeV, as well as in pp collisions at s=5.02TeV and 8 TeV. The cross section is obtained at midrapidity (|y|20GeV/c. How
We explore configurations of sufficient and necessary conditions for the evolution and resilience of borrower trust in their lenders. Because trust is a dynamic phenomenon that needs to be understood in terms of change over time, we rely on longitudinal data collected from managers of small- and medium-sized enterprises (SME) who are clients of cooperative banks operating in Austria and Finland, a
