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BackgroundThe essential trace elements copper and zinc, and their ratio (copper/zinc), are important for maintaining redox homeostasis. Previous studies suggest that these elements may impact breast cancer survival. However, no epidemiological study has so far been conducted on the potential association between copper and copper/zinc levels and survival after breast cancer diagnosis. In this study

Aim: Our aim was to investigate in a large population-based cohort study whether increased arterial stiffness and subclinical atherosclerosis in the coronary arteries differ at different stages of dysglycaemia. Methods: Data were obtained from SCAPIS, a population-based cohort of participants 50–64 years. The study population of 9379 participants was categorised according to glycaemic status: norm

Sepsis is a severe condition, representing a significant public health concern, especially in the elderly. There is, however, little insight into the potential effects of sociodemographic factors and comorbidities on sepsis incidence and how these factors interact. This was a nationwide open cohort study including individuals (N = 6746010) in Sweden ≥ 18 years of age spanning from 1997 to 2018, wi

BACKGROUND: The EAT-Lancet Commission proposed a global reference diet with both human health benefits and environmental sustainability in 2019. However, evidence regarding the association of such a diet with the risk of atrial fibrillation (AF) is lacking. In addition, whether the genetic risk of AF can modify the effect of diet on AF remains unclear. This study aimed to assess the association of

This paper advances a research agenda on how asset-based welfare policies, residential market volatility, stratified accumulation and vulnerability impinge upon the geography of inequality in property markets. Since the mid-1990s, housing prices have increased faster than the income of buyers, becoming a driver of social polarisation and household vulnerability. Few studies have however explicitly

Abstract Background: Osteoarthritis (OA) is a disabling joint disease affecting about 300 million people worldwide. Today, there is no cure for OA and treatment focuses on relieving symptoms. Guidelines recommend education, exercise, and weight control, as first-line treatment. In Sweden, first-line treatment is offered as a Supported Osteoarthritis Self-Management Programme (SOASP) combining educ

In recent years the possibility to increase maximum length and weight of heavy goods vehicles to allow for High Capacity Vehicles (HCVs) has been debated in Sweden. Proposals to increase maximum weight to 74 tonnes, and length to 34m have caused controversy. Key arguments among proponents are that HCVs will bring about benefits, such as: increasing energy efficiency and decreasing CO 2 emissions,

It has been hypothesized that to perform sensorimotor transformations efficiently, somatosensory information being fed back to a particular motor circuit is organized in accordance with the mechanical loading patterns of the skin that result from the motor activity generated by that circuit. Rearrangements of sensory information to different motor circuits could in this respect constitute a key co

Marine reptiles constitute a diverse group of secondarily aquatic tetrapods that have inhabited the world’s oceans for the greater part of the last 250 million years. While certain large-scale anatomical changes have been observed through progressive alterations of their skeletal morphology (e.g., the evolution of fin-like limbs), little is known about those changes that have occurred in the integ

The oxido-bridged diiron(III) complex [Fe2(μ-O)(μ-OAc)(DPEAMP)2](OCH3) (1), based on a new unsymmetrical ligand with an N4O donor set, viz. [2-((bis(pyridin-2-ylmethyl)amino)methyl)-6-((ethylamino)methyl)-4-methylphenol (HDPEAMP)], has been prepared and characterized by spectroscopic methods and X-ray crystallography. The crystal structure of the complex reveals that each Fe(III) ion is coordinate

Human cholangiocyte organoids are promising for regenerative medicine applications, such as repair of damaged bile ducts. However, organoids are typically cultured in mouse tumor-derived basement membrane extracts (BME), which is poorly defined, highly variable and limits the direct clinical applications of organoids in patients. Extracellular matrix (ECM)-derived hydrogels prepared from decellula

The human host defense peptide LL-37 has an essential role in the first line of defense against invading pathogens. This cathelicidin is mainly produced by immune cells and epithelial cells aligning the mucosal areas and is normally upregulated upon infection and inflammation. LL-37 displays direct antimicrobial activity against a variety of pathogens, but also modulates the immune responses by ac

Wine particle matter is mainly constituted by wine colloids and wine macromolecules. These wine colloidal and macromolecular compounds are barely studied, possibly due to the difficulty in facing the challenges that their study merits. These compounds are mainly formed by polyphenols, proteins and polysaccharides that come from the grape seeds, skins and pulp and even, to a lesser extent, from the

Recent attachment research attests that children’s relationships to preschool staff can contribute to their attachment development. The preschool introduction phase constitutes a natural arena for establishing these relationships, so organizing this introduction to enable relation-building between staff and children is essential. In Sweden, preschools stayed open during the covid-19-pandemic, howe

Background: Coronary flow reserve (CFR) is an index of coronary microcirculation. No previous reports exist on the association between testosterone levels and CFR. Therefore, the aim of the present study is to explore the association between testosterone and CFR in a group of men from the general population.Material and Methods: The study consisted of 66 men with no history of cardiovascular disea

This article examines the role of secrecy in relations between the NSU, the largest Danish national socialist youth organization, and parents. The NSU struggled to recruit and retain members from Danish families with and without national socialist convictions. By analysing how NSU media and internal correspondence framed parents’ reluctance to join, this article traces the changing functions of NS

We highlight important assumptions associated with the research program in sustainability science developed around “corporate biosphere stewardship” and the promise of “science-business initiatives.” In doing so, we interrogate a central concept in this research, “keystone actors.” We analyze the program based on associated research outputs and communications, focusing on three key challenges 1) i