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We analysed the human milk microbiome in a cohort of 80 lactating women and followed the dynamics in taxa over the course of lactation from birth to 6 months. Two hundred and thirty one milk samples were collected from full-term lactating women at 1, 4, 8 and 24 weeks following birth and analysed for microbiota composition using 16S rRNA sequencing. A significant decrease in milk microbiota divers
The 494 km long Latvian coast consists of sandy sediments, which serve as an excellent proxy for past coastal events and environment. Our study explores these understudied sediments along the western coast of the Gulf of Riga and combines two sand quartz-wise methods: optically stimulated luminescence (OSL) dating and grain microtextures. We provide a new chronology and microsedimentary results to
The central complex (CX), a remarkable brain region at the core of insect behaviors, has been the subject of extensive research for decades. In this review, we offer a comprehensive historical perspective on the anatomy, development, and function of the CX. The CX consists of discrete and highly structured neuropils found at the center of the brain, which are conserved across insects and arthropod
In unconventional superconductors, coupled charge and lattice degrees of freedom can manifest in ordered phases of matter that are intertwined. In the cuprate family, fluctuating short-range charge correlations can coalesce into a longer-range charge density wave (CDW) order which is thought to intertwine with superconductivity, yet the nature of the interaction is still poorly understood. Here, b
This study investigates subject use in [-topic shift] and [+topic shift] contexts in Standard Italian and Venetian - two close varieties which differ in their use of overt and null pronouns. In an acceptability judgment, we compare two groups of bilectals in their two varieties: children aged 7-12 years, divided in strong and weak dialect speakers, and an adult control group. All groups show diffe
A comprehensive study of the local and nonlocal amplitudes contributing to the decay B0 → K*0(→ K+π−)μ+μ− is performed by analysing the phase-space distribution of the decay products. The analysis is based on pp collision data corresponding to an integrated luminosity of 8.4 fb−1 collected by the LHCb experiment. This measurement employs for the first time a model of both one-particle and two-part
Body dysmorphic disorder (BDD) typically develops during adolescence, but there has been little research evaluating assessment tools for BDD in youth. This study sought to provide a comprehensive psychometric evaluation of a brief self-report questionnaire of BDD symptoms, the Body Image Questionnaire Child and Adolescent version (BIQ-C), in both clinical and non-clinical adolescent samples. Prope
The first aim of this chapter is to argue that Mary Wollstonecraft’s approach to inequalities of property and wealth is a form of “non-intrinsic egalitarianism”. The second aim is to nudge republican political theory in our own time towards accepting this approach as part of what freedom requires. Republican theory is not fit for purpose in our contemporary world unless it acknowledges economic in
Mutations in the PINK1 and PRKN genes are the most frequent genetic cause of early-onset Parkinson disease. The pathogenic p.R275W substitution in PRKN is the most frequent substitution observed in patients, and thus far has been characterized mostly through overexpression models that suggest a possible gain of toxic misfunction. However, its effects under endogenous conditions are largely unknown
A series of orthoborate-based ionic materials of bis(glycolato)borate ([BGB]) and bis(ethylene-1,2-dioxy)borate anions ([BEDB]) coupled with tetrabutylphosphonium ([P4444]) and tetrabutylammonium ([N4444]) cations have been synthesized, and their physicochemical properties are characterized. The ionic materials based on the most popular orthoborate anion, bis(oxalato)borate anion ([BOB]), which co
The model by D. Hu and D. Cai [Phys. Rev. Lett. 111, 138701 (2013). doi:10.1103/PhysRevLett.111.138701] describes the self-organization of vascular networks for transport of fluids from source to sinks. Diameters, and thereby, conductances, of vessel segments evolve so as to minimize a cost functional E . The cost is the trade-off between the power required for pumping the fluid and the energy con
The ultimate dream of unification models consists in combining both gauge and Yukawa couplings into one unified coupling. This is achieved by using a supersymmetric exceptional E6 gauge symmetry together with asymptotic unification in compact five-dimensional space-time. The ultraviolet fixed point requires exactly three fermion generations: one in the bulk, and the two light ones localised on the
The cellular polyamines spermine, spermidine, and their metabolic precursor putrescine, have long been associated with cell-growth, tumor-related gene regulations, and Alzheimer's disease. Here, we show by in vitro spectroscopy and AFM imaging, that these molecules promote aggregation of amyloid-beta (Aβ) peptides into fibrils and modulate the aggregation pathways. NMR measurements showed that the
Road traffic accidents cause nearly 1.3 million deaths and around 50 million injuries each year globally. Most organisations generate travel and transport, and influence thereby traffic safety. In Sweden, 47 percent of fatal accidents in road traffic are work-related, and 36 percent are linked to a procured transport service. Effective approaches to managing traffic safety in organisations have no
One of the most challenging aspects of stem cell research is the reliance on retrospective assays for ascribing function. This is especially problematic for hematopoietic stem cell (HSC) research in which the current functional assay that formally establishes its HSC identity involves long-term serial transplantation assays that necessitate the destruction of the initial cell state many months bef
We investigate the link between the internal microstructure of poly(N-isopropylacrylamide)-poly(ethylene glycol) methyl ether methacrylate (PNIPAM-PEGMA) microgels, their bulk moduli and the rheological response and structural arrangement in dense suspensions. The low degree of crosslinking combined with the increased hydrophilicity induced by the presence of PEGMA results in a diffuse, star-like
A modern vehicle typically has up to ten different heat exchangers, ensuring prolonged technology life, improved performance, and passenger comfort. Heat exchangers for automotive applications are made of multilayer-clad brazed aluminium. They are mature products, having been used in passenger and commercial internal combustion engine vehicles for decades, and their use will continue in electrifie
