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Microbial translocation has been linked to systemic immune activation during human immunodeficiency virus (HIV) type 1 infection. Here, we show that an elevated level of microbial translocation, measured as plasma lipopolysaccharide (LPS) concentration, correlates with AIDS in both individuals infected with HIV type 1 and individuals infected with HIV type 2. LPS concentration also correlates with
This paper explores the geography and structure of global innovation networks (GINs) of two multinational companies belonging to industries with different knowledge bases. It contributes to the existing literature on knowledge bases, by studying both intra-firm and inter-firm GINs. By means of social network analysis based on primary data, we identify two different forms of GINs, namely the global
A blend of rapeseed and butter oil was transesterified using immobilized Thermomyces lanuginosus lipase (Lipozyme (R) TL IM) as catalyst. The reaction was followed by reversed-phase HPLC and the triacylglycerol peaks were tentatively identified from their elution times by calculating equivalent carbon numbers. Further identification was made using HPLC-electrospray tandem mass spectrometry. A few
Trypsinogen is a serine proteinase produced mainly by the pancreas, but it has recently been found to be expressed also in several cancers such as ovarian and colon cancer and in vascular endothelial cells. In this study, we found that trypsinogen-1 and -2 are present at high concentrations (median levels, 0.4 and 0.5 mg/L, respectively) in human seminal fluid and purified them to homogeneity by i
BACKGROUND: The Case Method (Case) and Problem Based Learning (PBL) are two student active methods, increasingly used in medical education. AIM: The aim of this study was to compare medical student satisfaction with the two different active methods of learning and to see if there was any variation in preference between two stages in medical training. METHODS: A short questionnaire was given out to
The aim of this study was to illuminate the pattern of confusional episodes with regard to the content of elderly patients' actions and speech. Fifty-one (11.2%) out of 457 people admitted to an orthopaedic clinic developed acute confusional state. Non-participant direct observations and daily clinical bedside follow-up observations were made during the confusional episodes, focusing on the patien
Objective. To examine, in an inception cohort of systemic lupus erythematosus (SLE) patients, the association between neuropsychiatric (NP) events and anti-ribosomal P (anti-P), antiphospholipid (lupus anticoagulant [LAC], anticardiolipin), anti-beta 2-glycoprotein I, and anti-NR2 glutamate receptor antibodies. Methods. NP events were identified using the American College of Rheumatology case defi
The FUS gene at 16p11 fuses with DDIT3 and ATF1 as the result of translocations with chromosome band 12q13 in myxoid liposarcoma and angiomatoid fibrous histiocytoma, respectively, and with ERG as the result of a t(16;21)(p11;q22) in acute myeloid leukemia. We here show that a t(7;16)(q33;p11) in two cases of low grade fibromyxoid sarcoma fuses the FUS gene to BBF2H7, a previously uncharacterized
An illustrated key is presented for the fifteen West Palearctic species and subspecies of the genera Ctenophora, Dictenidia, Phoroctenia and Tanyptera, with a review of their distribution and an overview of the recent literature for these taxa.
Penelope Delta was a writer of books for children in the beginning of the twentieth century in Greece. Delta was active when the national project was at its peak. Delta's own participation in the national project consisted of writing for children in a vernacular language and belonging to a group of intellectuals actively promoting modernization in other aspects than only political and technologica
Popular Abstract in Swedish Fetma, övervikt och allergi är ett problem i många delar av världen och förändringar i tarmens bakterieflora kan vara en av flera orsaker. Människan har tio gånger fler mikroorganismer än mänskliga celler. Flest mikroorganismer finns i tarmen och de brukar gemensamt kallas för tarmfloran. Många bakterier är helt oskadliga och en del är dessutom nödvändiga för att vi tilThe gastrointestinal tract of the foetus is considered sterile but during vaginal birth the neonate comes into contact with bacteria from the maternal vaginal and intestinal microbiota. The main focus of this doctoral thesis was to elucidate the initial bacterial ecosystem in newborns and to relate microbial perturbations to physiological traits. The bacterial flora was mainly studied with molecu
Background: Despite the fact that old people´s technological needs have been payed much attention to in the last decennium, especially old users of information- and communication technology, technology has not found its natural place in research on ageing in modern societies. Purpose: This article examines to what extent social science research exist in the field of ageing and technology and where
Over the past 3.5 million years, there have been several intervals when climate conditions were warmer than during the pre-industrial Holocene. Although past intervals of warming were forced differently than future anthropogenic change, such periods can provide insights into potential future climate impacts and ecosystem feedbacks, especially over centennial-to-millennial timescales that are often
