Filetype
Mutations in the PINK1 and PRKN genes are the most frequent genetic cause of early-onset Parkinson disease. The pathogenic p.R275W substitution in PRKN is the most frequent substitution observed in patients, and thus far has been characterized mostly through overexpression models that suggest a possible gain of toxic misfunction. However, its effects under endogenous conditions are largely unknown
A series of orthoborate-based ionic materials of bis(glycolato)borate ([BGB]) and bis(ethylene-1,2-dioxy)borate anions ([BEDB]) coupled with tetrabutylphosphonium ([P4444]) and tetrabutylammonium ([N4444]) cations have been synthesized, and their physicochemical properties are characterized. The ionic materials based on the most popular orthoborate anion, bis(oxalato)borate anion ([BOB]), which co
The model by D. Hu and D. Cai [Phys. Rev. Lett. 111, 138701 (2013). doi:10.1103/PhysRevLett.111.138701] describes the self-organization of vascular networks for transport of fluids from source to sinks. Diameters, and thereby, conductances, of vessel segments evolve so as to minimize a cost functional E . The cost is the trade-off between the power required for pumping the fluid and the energy con
In neuroscience a number of new techniques have been developed by means of which it has become possible to study the activity of the living human brain. By means of these techniques we are beginning to understand the neurophysiology behind environmental attitudes and preferences. In addition to an introduction to cognitive neuroscience, this invited symposium contains a number of presentations, wh
[abstract missing]
The genre of the Periegesis is problematic, irrespective of whether it is brought into a generic category together with other works or is assumed to be sui generis. This paper argues that temporarily abandoning the scholarly habit of reading texts synoptically rather than subjecting oneself to one of the most fundamental characteristics of any text, viz. its linearity, may bring new light to the p
[abstract missing]
