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Efficacy of once-daily, high-dose, oral insulin immunotherapy in children genetically at risk for type 1 diabetes (POInT): a European, randomised, placebo-controlled, primary prevention trial

Background Type 1 diabetes begins with autoimmunity against pancreatic islet antigens, including insulin. The aim of the Primary Oral Insulin Trial (POInT) was to evaluate the efficacy and safety of daily high-dose oral insulin to prevent the development of islet autoantibodies and diabetes. Methods In this randomised, controlled, primary prevention trial, genetic screening in seven obstetric and

Reference_guide_doctoral_students_HT_faculties

Reference_guide_doctoral_students_HT_faculties Reference guide for third-cycle students at the Joint Faculties of Humanities and Theology at Lund University This is a general guide about doctoral studies at the Joint Faculties of Humanities and Theology (HT faculties). It consists of information about the programmes, funding (page 5), preparing to come, administrative formalities and life as a doc

https://www.mrs.lu.se/fileadmin/user_upload/historiska/hist/Avdelningar_Hist/MR/Forskarutbildning_MR/Reference_guide_doctoral_students_HT_faculties.pdf - 2026-06-06

MASM22/FMSN30/FMSN30F: Linear and Logistic Regression, 7.5hp FMSN40: … with Data Gathering, 9hp - Le

MASM22/FMSN30/FMSN30F: Linear and Logistic Regression, 7.5hp FMSN40: … with Data Gathering, 9hp - Lecture 7, spring 2026 Logistic regression: Probabilities, odds and odds ratios, Maximum-likelihood estimates, Wald test Introduction Logistic Maximum likelihood Properties MASM22/FMSN30/FMSN30F: Linear and Logistic Regression, 7.5 hp FMSN40: . . . with Data Gathering, 9 hp Lecture 7, spring 2026 Logi

https://www.maths.lu.se/fileadmin/maths/matematisk_statistik/FMSN30_FMSN40_MASM22/lecture_07_vt26.pdf - 2026-05-09

Dr

Dr 1 Satu Manninen Professor in English language and linguistics, 2012 Docent in general linguistics, 2005 Ph.D theoretical linguistics, 1999 MA in English Philology, 1993 List of publications Books: Manninen, S., Turner, E. & C. Wadsö Lecaros (2020) Writing in English at University: A Guide for Second Language Writers. Lund Studies in English 120. ISBN (print) 978-91-89213-14-2 ISBN (e- version)

https://www.sol.lu.se/media/documents/persons/SatuManninen/Combined_publications_S_Manninen_Autumn_2024_1.pdf - 2026-06-11

"Hur vi kan utbilda lärare i bild så att barn och ungdomar får goda redskap för att möta dagens och

"Hur vi kan utbilda lärare i bild så att barn och ungdomar får goda redskap för att möta dagens och framtidens bildsamhälle." Master Narratives and the (Pictorial) Construction of Otherness – Anti-Semitic Images in the Third Reich and Beyond Michael Ranta (Div. of Cognitive Semiotics, Lund University, Sweden) 1 Research Project: The Making of Them and Us (MaTUs) - Cultural Encounters Conveyed Thro

https://projekt.ht.lu.se/fileadmin/_migrated/content_uploads/RANTA_CCS_Nazi__2016_2_01.pptx - 2026-06-11

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Handbok för skyddsombud Sacorådet Göteborgs stad 2014 Regelverk och tips inom arbetsmiljöområdet Arbetsmiljölagen Arbetsmiljöförordningen Arbetsmiljöverkets föreskrifter (AFS) Kommunen som arbetsgivare Arbetsgivarens ansvar Arbetstagarens ansvar Skyddsombudet Skyddskommitté Systematiskt arbetsmiljöarbete på arbetsplatsen Rehabilitering Arbetsmiljöverkets roll (AV) Andra aktörer på området Till dig

https://www.saco.se/globalassets/lokala-akademikerforeningar/kommun-och-region/goteborgs-stad/dokument/ny-handbok-for-skyddsombud-regelverk-130820saco.pdf - 2026-06-12

XFEL Microcrystallography of Self-Assembling Silver n-Alkanethiolates

New synthetic hybrid materials and their increasing complexity have placed growing demands on crystal growth for single-crystal X-ray diffraction analysis. Unfortunately, not all chemical systems are conducive to the isolation of single crystals for traditional characterization. Here, small-molecule serial femtosecond crystallography (smSFX) at atomic resolution (0.833 Å) is employed to characteri

Comparative proteome analysis revealing an 11-protein signature for aggressive triple-negative breast cancer

BACKGROUND: Clinical outcome of patients with triple-negative breast cancer (TNBC) is highly variable. This study aims to identify and validate a prognostic protein signature for TNBC patients to reduce unnecessary adjuvant systemic therapy.METHODS: Frozen primary tumors were collected from 126 lymph node-negative and adjuvant therapy-naive TNBC patients. These samples were used for global proteom

The Gaia-ESO Survey: Evidence of atomic diffusion in M67

Investigating the chemical homogeneity of stars born from the same molecular cloud at virtually the same time is very important for our understanding of the chemical enrichment of the interstellar medium and with it the chemical evolution of the Galaxy. One major cause of inhomogeneities in the abundances of open clusters is stellar evolution of the cluster members. In this work, we investigate va

Dietary Folate Intake and Breast Cancer Risk: European Prospective Investigation Into Cancer and Nutrition

There is limited evidence on the association between dietary folate intake and the risk of breast cancer (BC) by hormone receptor expression in the tumors. We investigated the relationship between dietary folate and BC risk using data from the European Prospective Investigation into Cancer and Nutrition (EPIC). A total of 367993 women age 35 to 70 years were recruited in 10 European countries. Dur

Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype.

Insufficient oxygen and nutrient supply often restrain solid tumor growth, and the hypoxia-inducible factors (HIF) 1 alpha and HIF-2 alpha are key transcription regulators of phenotypic adaptation to low oxygen levels. Moreover, mouse gene disruption studies have implicated HIF-2 alpha in embryonic regulation of tyrosine hydroxylase, a hallmark gene of the sympathetic nervous system. Neuroblastoma

The Role of Smoking and Diet in Explaining Educational Inequalities in Lung Cancer Incidence.

Background Studies in many countries have reported higher lung cancer incidence and mortality in individuals with lower socioeconomic status. Methods To investigate the role of smoking in these inequalities, we used data from 391 251 participants in the European Prospective Investigation into Cancer and Nutrition study, a cohort of individuals in 10 European countries. We collected information on

Ovarian cancer and oral contraceptives: collaborative reanalysis of data from 45 epidemiological studies including 23 257 women with ovarian cancer and 87 303 controls

Background Oral contraceptives were introduced almost 50 years ago, and over 100 million women currently use them. Oral contraceptives can reduce the risk of ovarian cancer, but the eventual public-health effects of this reduction will depend on how long the protection lasts after use ceases. We aimed to assess these effects. Methods Individual data for 23 257 women with ovarian cancer (cases) a

Inflammatory potential of the diet and risk of colorectal cancer in the European Prospective Investigation into Cancer and Nutrition study

Proinflammatory diets are associated with risk of developing colorectal cancer (CRC), however, inconsistencies exist in subsite- and sex-specific associations. The relationship between CRC and combined lifestyle-related factors that contribute toward a low-grade inflammatory profile has not yet been explored. We examined the association between the dietary inflammatory potential and an inflammator

The Gaia-ESO survey : Matching chemodynamical simulations to observations of the Milky Way

The typical methodology for comparing simulated galaxies with observational surveys is usually to apply a spatial selection to the simulation to mimic the region of interest covered by a comparable observational survey sample. In this work, we compare this approach with a more sophisticated post-processing in which the observational uncertainties and selection effects (photometric, surface gravity

Host-pathogen adhesion as the basis of innovative diagnostics for emerging pathogens

Infectious diseases are an existential health threat, potentiated by emerging and re-emerging viruses and increasing bacterial antibiotic resistance. Targeted treatment of infectious diseases re-quires precision diagnostics, especially in cases where broad-range therapeutics such as antibiotics fail. There is thus an increasing need for new approaches to develop sensitive and specific in vitro dia

Hepatocellular Carcinoma Risk Factors and Disease Burden in a European Cohort: A Nested Case-Control Study.

Background: To date, no attempt has been made to systematically determine the apportionment of the hepatocellular carcinoma burden in Europe or North America among established risk factors.MethodsUsing data collected from 1992 to 2006, which included 4 409 809 person-years in the European Prospective Investigation into Cancer and nutrition (EPIC), we identified 125 case patients with hepatocellula

Beyond ΛCDM : Problems, solutions, and the road ahead

Despite its continued observational successes, there is a persistent (and growing) interest in extending cosmology beyond the standard model, ΛCDM. This is motivated by a range of apparently serious theoretical issues, involving such questions as the cosmological constant problem, the particle nature of dark matter, the validity of general relativity on large scales, the existence of anomalies in