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Background: Ultrafiltration (UF) insufficiency in peritoneal dialysis (PD) often leads to transfer to hemodialysis. Therefore, strategies to prolong time on therapy are needed. The use of a combined crystalloid and colloid solution, also called bimodal PD, can help improve UF. Methods: We propose a method for reconstituting bimodal solutions. Three bimodal PD solutions, with respectively 100 ml (s
In this paper, we aim to understand how perceptions of adult learning and continued vocational education and training (CVET) are related to participation in these activities. Specifically, participation within the previous 12 months in different kinds of adult learning and CVET is analysed, distinguishing between (1) formal, (2) non-formal work-related, (3) non-formal non-work-related, and (4) inf
In this report, we analyse attrition at the two most recent data collection points of the longitudinal Swedish project “Deliberate self-harm, emotion regulation, and interpersonal relations in youth”, that collected survey data from the same cohort in 2007 (T1), 2008 (T2), 2017 (T3), and 2023 (T4). We compared T4 responders and non-responders using variables assessed at T1−T3, and T3 responders an
Based on a new deep drilling on southern Gotland (Sweden), this study is the first to document the carbon isotope chemostratigraphy of the Upper Ordovician through lowermost Silurian sedimentary record from the central parts of the Baltic Sea subsurface. The lithological record of the Stora Sutarve core has similarities with adjacent successions in both the Viki core in the East Baltic area and th
The initial Swedish discourse of transnational adoption as a win-win situation has changed over its more than 60-year-long history. This article aims to trace and present some themes in this history, with a particular focus on the public debate and the different narratives that representatives of the adoption triangle—the adoptees, the adoptive parents, and the biological parents—tell when dealing
BACKGROUND: Accumulating studies reported that several phosphodiesterases (PDEs) inhibitors might have cardiovascular benefits.OBJECTIVES: This study aimed to explore the relationship between genetically-predicted PDEs and ischemia heart disease via drug target Mendelian randomization (MR) approach, and then examine the effect of inhibitors of identified target on the outcomes by using real-world
This paper presents a novel approach to modeling the gradual reduction in heat demand and the evolving expansion of district heating (DH) grids for assessing the DH potential in EU member states (MS). It introduces new methodological elements for modeling the impact of connection rates below 100% on heat distribution costs in both dense and sparse areas. The projected heat demand in 2050 is derive
Objective. Despite the growing interest in understanding the role of triggers of paroxysmal atrial fibrillation (AF), solutions beyond questionnaires to identify a broader range of triggers remain lacking. This study aims to investigate the relation between triggers detected in wearable-based physiological signals and the occurrence of AF episodes. Approach. Week-long physiological signals were co
Background: Tau-PET is a diagnostic tool with high sensitivity and specificity for discriminating Alzheimer’s disease (AD) dementia from other neurodegenerative disorders in well-controlled research environments. The role of tau-PET in real-world clinical practice, however, remains to be established. The aim of the TAP-TAU study is therefore to investigate the impact of tau-PET in clinical practic
Flight behaviours of birds have been extensively studied from different angles such as their kinematics, aerodynamics and, more generally, their migration patterns. Nevertheless, much is still unknown about the daily foraging flight activity and behaviour of breeding birds, and potential differences among males and females. The recent development of miniaturized accelerometers allows us a glimpse
The Adverse Outcome Pathways (AOPs) framework is pivotal in toxicology, but the, terminology describing Key Event Relationships (KERs) varies within AOP guidelines.This study examined the usage of causal, observational and predictive terms in AOP, documentation and their adaptation in AOP development. A literature search and text, analysis of key AOP guidance documents revealed nuanced usage of th
Wireless Sensor Networks (WSNs) enhance the ability to sense and control the physical environment in various applications. The functionality of WSNs depends on various aspects like the localization of nodes, the strategies of node deployment, and a lifetime of nodes and routing techniques, etc. Coverage is an essential part of WSNs wherein the targeted area is covered by at least one node. Computa
Infant and adult MLL1/KMT2A-rearranged (MLLr) leukemia represents a disease with a dismal prognosis. Here, we present a functional and proteomic characterization of in utero-initiated and adult-onset MLLr leukemia. We reveal that fetal MLL::ENL-expressing lymphomyeloid multipotent progenitors (LMPPs) are intrinsically programmed towards a lymphoid fate but give rise to myeloid leukemia in vivo, hi
In response to concerns about depleting natural resources, organisations are developing eco-friendly products and services. This study examines the role of manufacturing industries and services in sustainable resource utilisation, focusing on the Micro, Small, Medium Enterprises (MSME) sector, a significant contributor to global Gross Domestic Product (GDP). Using Life Cycle Assessment (LCA) metho
Feminism has become a recurrent ingredient in many women's narratives of their selves and is regularly appearing as an important aspect of women's success, happiness and self‐realization. The development has been criticized for upholding a view in which structural inequalities are explained in terms of individual choices; choice feminism. This article examines two professional groups, lifestyle in
