Search results

Review of Tadhg O’Keeffe, “Archaeology and the Pan-European Romanesque” (London 2007).

PRELP (proline, arginine-rich end leucine-rich repeat protein) is an extracellular matrix leucine-rich repeat protein. The amino-terminal region of PRELP differs from that of other leucine-rich repeat proteins in containing a high number of proline and arginine residues. The clustered proline and basic residues are conserved in rat, bovine, and human PRELP. Although the function of PRELP is not ye

Members of the PAR-1/MARK kinase family play critical roles in polarity and cell cycle control and are regulated by 14-3-3 scaffolding proteins, as well as the LKB1 tumour suppressor kinase and atypical protein kinase C (PKC). In this study, we initially investigated the mechanism underlying the interaction of mammalian MARK3 with 14-3-3. We demonstrate that 14-3-3 binding to MARK3 is dependent on

The paper introduces the philosophy and current status of a benchmark for the evaluation of control strategies in wastewater treatment plants and also the forthcoming developments and future perspectives. The work has been carried out within the framework of two COST Actions (682 and 624) and in close collaboration with the IWA Task Group on Respirometry. The benchmark is a platform-independent si

Animal eyes that are primarily used under low-light conditions usually have optical systems of short depth of focus, such that chromatic defocus may lead to considerable blurring of the images. In some vertebrates, the problem is solved by multifocal lenses having concentric zones of different focal lengths, each of which focuses a different relevant spectral range onto the retina. A partially con

As part of a multidisciplinary study, the rate of autism spectrum disorder (ASD), learning disability (LD), and brain abnormalities was examined in 20 participants (12 males, 8 females; age range 8mo-17y, mean age 8y 1mo) diagnosed as falling within the oculoauriculovertebral spectrum (OAV). A neuropsychiatric examination was performed, including standardized autism diagnostic interviews. Two indi

High-resolution palaeoecological proxies of pollen, macrofossils and diatoms from an isolation lake provide a long-term record of the Holocene landscape history and shoreline displacement on the Biskopsmala Peninsula in central Blekinge, SE Sweden. During the Preboreal/Boreal transition, the peninsula was sparsely vegetated by woodlands, along with lateglacial dwarf shrub/steppe communities. The l

Results of the Jefferson Lab Hall A quasielastic 3He(e,ep)pn measurements are presented. These measurements were performed at fixed transferred momentum and energy, q=1502 MeV/c and =840 MeV, respectively, for missing momenta pm up to 1 GeV/c and missing energies in the continuum region, up to pion threshold; this kinematic coverage is much more extensive than that of any previous experiment. The

Europe has positioned itself as a front runner for climate mitigation policy globally. However, to reach climate mitigation targets that go far beyond Kyoto commitments, climate policy must become more integrated with sectoral policies such as energy, transport and agriculture. To achieve such policy integration, policy refraining and dilemma sharing among sectoral actors are important mechanisms.

The interactions, in aqueous media, between a pyrene-labelled polyelectrolyte poly(acrylic acid) (PAAMePy) with two different degrees of labelling and beta- and gamma-cyclodextrins (beta- and gamma-CD) were studied using absorption and fluorescence (steady-state and time-resolved) techniques. In addition to qualitative and quantitative parameters obtained from absorption and steady-state fluoresce

Type 2 diabetic patients are at increased risk to develop atherosclerotic vascular disease. These patients are often treated with sulphonylurea derivatives, and it has been suggested that this treatment might contribute to the increased atherosclerotic process. The aim of the present study was therefore to investigate whether tolbutamide influences lipid metabolism in such a way that the atheroscl

The influence of sodium dodecyl sulfate (SDS) on the interfacial behavior of two amphiphilic polyelectrolytes, which are copolymers of the cationic monomers triethyl(vinylbenzyl)ammonium chloride and dimethyldodecyl(vinylbenzyl)ammonium chloride, at the silica-aqueous interface was studied. The fraction of amphiphilic monomers was varied, where ODT, 40DT, and 80DT contained 0, 40, and 80 mol % mon

In a simulation model we investigated how much of the initial genetic variation that is retained in a population after a dominant mutation has brought apomixis to fixation in it. A marker allele associated with the apomixis mutation is generally retained after the fixation of apomixis, particularly if the two alleles are closely linked. The spread of asexuality, however, normally leads to almost n

The Sahel region of Africa has experienced a decrease in rainfall from the early 1960s to mid 1990s. Recent studies have detected an increased in NDVI amplitude and growing season integrated NDVI for the region since 1982. However, these studies have not examined how plant phenology has changed. Phenology examines life cycle events such as bud burst and leaf senescence. Using the software TIMESAT

We revise the statistical foundations of the reverse Monte Carlo ( RMC) technique by constructing the associated functional of a variational principle which incorporates, without any ad hoc assumptions, the inherent errors accompanying the simulation and the experimental data. We propose a Bayesian criteria for acceptance/rejection of configurations, in terms of the variations of the functional. T

Age-adjusted incidence rates of breast cancer vary more than 10-fold worldwide, with the highest rates reported in North America and Europe. The highest breast cancer incidence rates in Southeast Asia have been reported for the Manila Cancer Registry in the Philippines, with an age-standardized rate of 47.7 per 100,000 per year. The possible contribution of hereditary factors to these elevated rat

OBJECTIVE: The acute-phase inflammatory response is closely correlated with the development of rheumatoid arthritis, but the pathophysiologic role of its specific components is largely unknown. We investigated the genetic control of the acute-phase protein response in pristane-induced arthritis (PIA), which is a chronic erosive arthritis model in rats. METHODS: Plasma levels of the acute-phase pro

The iron-regulatory hormone hepcidin has been proposed as the mediator of anemia of inflammation (AI). We examined the acute and chronic effects of hepcidin in the mouse. Injections of human hepcidin (50 microg/mouse), but not of its diluent, induced hypoferremia within 4 hours. To examine the chronic effects of hepcidin, we implanted either tumor xenografts engineered to overexpress human hepcidi