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Identification of ETV6-RUNX1-like and DUX4-rearranged subtypes in paediatric B-cell precursor acute lymphoblastic leukaemia

Fusion genes are potent driver mutations in cancer. In this study, we delineate the fusion gene landscape in a consecutive series of 195 paediatric B-cell precursor acute lymphoblastic leukaemia (BCP ALL). Using RNA sequencing, we find in-frame fusion genes in 127 (65%) cases, including 27 novel fusions. We describe a subtype characterized by recurrent IGH-DUX4 or ERG-DUX4 fusions, representing 4%

Lung Transplantation: Clinical and experimental studies

Popular Abstract in Swedish Transplantation av lungor är ett relativt nytt behandlingsalternativ vid svår lung-sjukdom. Den första lungtransplantationen på människa gjordes 1963. Patienten dog efter 18 dagar i njursvikt. Mellan 1963 och 1980 gjordes ca 40 lungtransplantationer i världen med nedslående resultat. Medianöverlevnaden var enbart 8,5 dagar och den patient som levde längst levde bara 6 mDuring the past 15 years lung transplantation has been established as a therapeutic option for patients with end-stage pulmonary disease. The results have improved over time and some transplantation centers now show 1-year survival rates above 80%. The number of donors has remained relatively constant during later years but the demand is increasing resulting in longer waiting times and an increasi

Review of particle physics

This biennial Review summarizes much of Particle Physics Using data from previous editions, plus 2205 new measurements from 667 papers, we list, evaluate, and average measured properties of gauge bosons, leptons, quarks, mesons, and baryons We also summarize searches for hypothetical particles such as Higgs bosons, heavy neutrinos, and supersymmetric particles All the particle properties and searc

GISCOME – Genetics of Ischaemic Stroke Functional Outcome network : A protocol for an international multicentre genetic association study

Introduction: Genome-wide association studies have identified several novel genetic loci associated with stroke risk, but how genetic factors influence stroke outcome is less studied. The Genetics of Ischaemic Stroke Functional outcome network aims at performing genetic studies of stroke outcome. We here describe the study protocol and methods basis of Genetics of Ischaemic Stroke Functional outco

Mechanism of phage sensing and restriction by toxin-antitoxin-chaperone systems

Toxin-antitoxins (TAs) are prokaryotic two-gene systems composed of a toxin neutralized by an antitoxin. Toxin-antitoxin-chaperone (TAC) systems additionally include a SecB-like chaperone that stabilizes the antitoxin by recognizing its chaperone addiction (ChAD) element. TACs mediate antiphage defense, but the mechanisms of viral sensing and restriction are unexplored. We identify two Escherichia

The centrality of doubting and checking in the network structure of obsessive-compulsive symptom dimensions in youth

Objective. Obsessive-compulsive disorder (OCD) is a heterogeneous condition with well-established symptom dimensions across the lifespan. The objective of the present study was to use network analysis to investigate the internal structure and central features of these dimensions in unselected schoolchildren and in youth with OCD.Method. We estimated the network structure of OCD symptom dimensions

Solvent-Dependent Structural Dynamics in the Ultrafast Photodissociation Reaction of Triiodide Observed with Time-Resolved X-ray Solution Scattering

Resolving the structural dynamics of bond breaking, bond formation, and solvation is required for a deeper understanding of solution-phase chemical reactions. In this work, we investigate the photodissociation of triiodide in four solvents using femtosecond time-resolved X-ray solution scattering following 400 nm photoexcitation. Structural analysis of the scattering data resolves the solvent-depe

Eosinophils—from cradle to grave

Over the past years, eosinophils have become a focus of scientific interest, especially in the context of their recently uncovered functions (e.g. antiviral, anti-inflammatory, regulatory). These versatile cells display both beneficial and detrimental activities under various physiological and pathological conditions. Eosinophils are involved in the pathogenesis of many diseases which can be class

In Situ Detection of Programmed Cell Death Protein 1 and Programmed Death Ligand 1 Interactions as a Functional Predictor for Response to Immune Checkpoint Inhibition in NSCLC

Introduction: Immune checkpoint inhibitors (ICIs) have transformed lung cancer treatment, yet their effectiveness seem restricted to certain patient subsets. Current clinical stratification on the basis of programmed death ligand 1 (PD-L1) expression offers limited predictive value. Given the mechanism of action, directly detecting spatial programmed cell death protein 1 (PD1)–PD-L1 interactions m

Årsberättelse 2022 LTH

Årsberättelse 2022 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET Årsberättelse 2022 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET Årsberättelse 2022 LTH | LUNDS TEKNISKA HÖGSKOLA | LUNDS UNIVERSITET FO T O : C A M IL LA L E K E B JE R Förord: Tillsammans utforskar och skapar vi – till nytta för världen 5............................................................................. LTH – åre

https://www.lth.se/fileadmin/lth/omlth/vb/TA-aarsberaettelse2022-LTH.pdf - 2026-04-23

Lunds universitets exportkontrollprogram - efterlevnadsprogram för produkter med dubbla användningso

Microsoft Word - Lunds universitets exportkontrollprogram_STYR2020_2073_tillg Sida 1 av 22 Rektor BESLUT Diarienummer STYR 2020/2073 Datum 2021-10-21 Lunds universitets exportkontrollprogram – efterlevnadsprogram för produkter med dubbla användningsområden Fastställt av rektor 2021-10-21. Postadress Box 117 Besöksadress Sandgatan 5 Telefon 046-222 69 29, 046-222 00 00 E-post robert.collin@bygg.lu.

https://www.medarbetarwebben.lu.se/sites/medarbetarwebben.lu.se/files/2021-12/Lunds-universitets-exportkontrollprogram-efterlevnadsprogram-for-produkter-med-dubbla-anvandningsomraden.pdf - 2026-04-23

Studentbokningar

Studentbokningar | LTH, Lunds Tekniska Högskola Hoppa till huvudinnehåll Vi använder cookies och andra spårningsteknologier för att förbättra användarupplevelsen på vår webbplats, för att visa dig personligt innehåll och riktade annonser och för att analysera vår webbplatstrafik. Läs mer om cookies. Absolut nödvändiga cookies Dessa cookies är nödvändiga för att webbplatsen ska fungera och kan inte

https://www.lth.se/lthin/schemalaeggninglokalbokning-paa-lth/studentbokningar/ - 2026-04-23

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Rapport från studiebesök i Lissabon, Portugal, april 2019 Sacos fackliga stipendiefond Författare Stefan Gudmundsson, Sveriges Ingenjörer Hans Franklin, Civilekonomerna Maj 2019 Innehållsförteckning 1. Syftet med resan 2. Bakgrund 3. Rapportförfattarna 4. Reseberättelse - aktiviteter och deras ändamål 5. Erfarenheter och slutsatser 1. Syftet med resan Sverige och Portugal är två länder med jämnsto

https://www.saco.se/globalassets/bilder-video-och-dokument/om-saco/sacos-fackliga-stipendiefond/2019_civ.ek-sv.ing.-portugal-lissabon.pdf - 2026-04-23

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23 Climate Displacement in African Cities Kampala City Profile ISBN 978-91-86910-69-3 Climate Displacement in African Cities - Kampala City Profile © 2023 Raoul Wallenberg Institute of Human Rights and Humanitarian Law A partnership between: This publication was produced through a collaboration between Lund University, the Raoul Wallenberg Institute of Human Rights and Humanitarian Law, and local

https://rwi.lu.se/wp-content/uploads/2023/12/Kampala-city-profile-FINAL.pdf - 2026-04-24

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Remembering Ideological Identities: Transference of Holocaust Memory through Artistic Expression A Master’s Thesis for the Degree Master of Arts (Two Years) in Visual Culture Tania Norell Division of Art History and Visual Studies Department of Arts and Cultural Sciences Lund University, Sweden KOVM12, Master Thesis, 30 credits Supervisor: Professor Max Liljefors, Lund University Examiner: Associa

https://www.ctr.lu.se/media/documents/persons/TaniaNorell/Tania_Norell_MA_THESIS_2014.pdf - 2026-04-24

Discovery and engineering of the antibody response to a prominent skin commensal

The ubiquitous skin colonist Staphylococcus epidermidis elicits a CD8+ T cell response pre-emptively, in the absence of an infection1. However, the scope and purpose of this anticommensal immune programme are not well defined, limiting our ability to harness it therapeutically. Here, we show that this colonist also induces a potent, durable and specific antibody response that is conserved in human

Consumption of vegetables and fruits and risk of breast cancer

Context The intake of vegetables and fruits has been thought to protect against breast cancer. Most of the evidence comes from case-control studies, but a recent pooled analysis of the relatively few published cohort studies suggests no significantly reduced breast cancer risk is associated with vegetable and fruit consumption. Objective To examine the relation between total and specific vegetable

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LUNDS UNIVERSITET Sida 1 av 5 HUMANISTISKA OCH TEOLOGISKA FAKULTETERNA PROTOKOLL Diarienummer STYR 2025/1837 Sammanträdesdatum 2025-08-27 kl 10.00 -11.00 Fakultetsstyrelsens arbetsutskott Arbetsutskottets sammanträde 2025-08-27 Ledamöter Närvarande Sara Håkansson, universitetslektor, prodekan, ordförande §5-8 Alexander Maurits, universitetslektor, prodekan Johannes Persson, professor, dekanus, ord

https://www.ht.lu.se/fileadmin/user_upload/ht/dokument/Fakulteterna/protokoll/AU/Protokoll_AU_250827_justerat.pdf - 2026-04-09

Microsoft Word - HILMA 2009-11-11.doc

Microsoft Word - HILMA 2009-11-11.doc HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 35, 2009/10, Nr 5, 2009-11-11 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat p

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_ht09_5_03.pdf - 2026-04-23

HILMA 2010-08-30

HILMA 2010-08-30 HILMA Historiska Institutionen i Lund Meddelar Att… Årgång 36, 2010/11, Nr 1, 2010-08-30 Underlagen till HILMA förvaras i pärmar som står i rum 209, på hyllan ovanför faxen. Där hittar du ytterligare information om seminarier, anställningsvillkor, stipendier och annat samt ansök- ningsblanketter i förekommande fall. De sistnämnda, som är samlade i en separat pärm, kopierar du och

https://www.hist.lu.se/fileadmin/_migrated/content_uploads/hilma_ht10_1_03.pdf - 2026-04-23