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Popular Abstract in Swedish Den engelska medeltidsdikten Pearl studeras främst mot bakgrund av Pseudo-Dionysius tankar samt den samtida kontemplativa litteraturen (d v s Julian of Norwich, Margery Kempe, Walter Hilton, Richard Rolle och den okände författaren av The Cloud of Unknowing). Det är framförallt med avseende på medeltida teologiska frågor om människans möjlighet och begränsing att förståThis dissertation places Pearl in the context of works by the English fourteenth-century contemplative writers (‘mystics’), as well as of patristic and other theological treatises, focusing on the theme of comprehending and speaking about a transcendent divine dimension. The purpose is to show that Pearl and the works of Julian of Norwich, Margery Kempe, Walter Hilton, Richard Rolle and the author

Popular Abstract in Swedish Denna avhandling behandlar organisatoriska aspekter som organisationsklimat, psykologiskt klimat samt medarbetarskap utifrån ledarskapsbeteende, arbetskamratsbeteende och interaktivt ledare-följarebeteende. Den sistnämnda faktorn handlar både om ledarens och följarens (medarbetarens, arbetskamratens) beteende och om dessa är samstämmiga (kongruenta) eller skilda. AvhandThis doctoral dissertation was driven by an inspiration to study how employees behave toward each other from an interactive perspective where all members of an organization are considered active contributors. Employeeship holds this perspective and acknowledges the importance of productive relationships. The objective of this dissertation is to contribute to the conceptual and methodological devel

The type and potency of an immune response provoked during vaccination will determine ultimate success in disease prevention. The basis for this response will be the design and implementation of antigen presentation to the immune system. Whereas direct antigen administration will elicit some form of immunological response, a more sophisticated approach would couple the antigen of interest to a vec

PURPOSE: Sclerosing epithelioid fibrosarcoma (SEF) is a highly aggressive soft tissue sarcoma closely related to low-grade fibromyxoid sarcoma (LGFMS). Some tumors display morphological characteristics of both SEF and LGFMS, so called hybrid SEF/LGFMS. Despite the overlap of gene fusion variants between these two tumor types, SEF is much more aggressive. The present study aimed to further characte

The aim of the thesis The Court Service in Sweden. Regulation and Development 1684-1989 is to investigate the special church service which was decreed by Swedish law in connection with trials in law courts between 1684 and 1989. The service was initiated by King Karl XI of Sweden in 1684 by a letter to the Bishop of Västerås Diocese. Initially, the service was held only within parts of the Dioces

Mucins are high-molecular-weight glycoproteins and major constituents of the mucus layer which covers the airway surface. We have studied the interactions between bacteria, mucins, and epithelial cells from the human respiratory tract. Nontypeable strains of Haemophilus influenzae were found to bind to purified airway mucins in suspension and on solid phase. Mucins in suspension inhibited the atta

The thesis deals with the representation of fantasy in modern film with special regards to parallel-world stories. In order to demarcate parallel worlds from other types of magical worlds in fantasy stories, the thesis contains an extensive chapter of definitions. Starting out with Todorov’s and Jackson’s well-known theories on fantasy / the fantastic, the thesis turns to other approaches allowing

Popular Abstract in Swedish Prostatacancer är den vanligaste formen av cancer hos män i Sverige och ungefär 10 000 män diagnosticeras årligen. Prostatacancer tros orsakas av en kombination av ärftliga faktorer och miljö-/livsstilsfaktorer. De enda väletablerade riskfaktorerna för prostatacancer är ålder, etnicitet och ärftlighet inom familjer. För att kunna arbeta med förebyggande av denna sjukdomProstate cancer (PCa) is a heterogenous disease including very aggressive lethal tumors to incidentally discovered clinically insignificant tumors. Age, ethnicity, and family history are the only established risk factors. Type 2 diabetes mellitus (T2D) has been found to associate with increased overall cancer risk but with lower risk of specifically PCa. T2D is initially associated with increased

Popular Abstract in Swedish Immunsystemet är ett invecklat och komplext system som finns överallt i kroppen och som inte är begränsat till ett enda organ. Vi utsätts hela tiden för ”angrepp” från mikro-organismer (t.ex. bakterier eller virus) men också för främmande ämnen som kan vara skadliga eller giftiga. Immunsystemets huvudfunktion är att hjälpa kroppen att känna igen dessa ”angripare” och atThe overall aim of this PhD project was to gain insight into the incidence of primary immunodeficiency (PID) in southern Sweden and to optimize diagnostic and treatment measures for these patients. We estimated the occurrence rate of PID in the pediatric population of southern Sweden during a period of 4 years and described the demographic, clinical and immunological characteristics of the identif

The O, N, and C 1s core level photoemission spectra of the nucleobases cytosine and uracil have been measured in the vapor phase, and the results have been interpreted via theoretical calculations. Our calculations accurately predict the relative binding energies of the core level features observed in the experimental photoemission results and provide a full assignment. In agreement with previous

Popular Abstract in Swedish Nattfjärilshannars beteenden och doftupplevelser i feromonplymer Denna skrift avhandlar mekanismerna bakom så kallad förvirringsbekämpning av skadegörande nattfjärilar med hjälp av deras sexualferomon. Nattfjärilar är egentligen en lite felaktig benämning på de fjärilar som inte är dagfjärilar. I Sverige finns det 116 arter dagfjärilar och mer än 2400 arter ’nattfjäriBehaviour of male moths and electrophysiological responses of male pheromone-specific olfactory receptor neurones were studied in two model species, the oriental fruit moth Grapholita molesta and the turnip moth Agrotis segetum. The studies were aimed at elucidating the relative importance of different mating disruption mechanisms. In a wind tunnel study of G. molesta, behavioural response to a r

This paper introduces the idea that location based pervasive games can be used to make mobility training for visually impaired children more fun. The user centred development process which has been carried out in collaboration with both visually impaired children and rehabilitation staff is described and we present a novel game concept which combines locative play, sound traces and a physical catc

Sverige är ett utpräglat småföretagarland och mätt i antal bedrivs en klart övervägande del av företagen som enskild näringsverksamhet. Till skillnad från aktiebolag och andra juridiska personer, som hänför alla inkomster till inkomstslaget näringsverksamhet, ska inkomster eller utgifter för fysiska personer hänföras till endera av inkomstslagen näringsverksamhet, tjänst eller kapital. AvhandlingeSweden is a typical small-business country and, based on the numbers, a clear majority of the companies operate as sole traders. Unlike limited companies and other legal entities, which classify all income as business income, the income or expenditures of private persons are classified as either business, service or capital income. The main objective of this thesis is to systematically examine the

Metformin is a first-line oral agent used in the treatment of type 2 diabetes, but glycaemic response to this drug is highly variable. Understanding the genetic contribution to metformin response might increase the possibility of personalising metformin treatment. We aimed to establish the heritability of glycaemic response to metformin using the genome-wide complex trait analysis (GCTA) method.

Post-translational modifications of proteins significantly affect their structure and function. The carbamylation of positively charged lysine residues to form neutral homoitrulline occurs primarily under inflammatory conditions through myeloperoxidase-dependent cyanate (CNO-) formation. We analyzed the pattern of human IgG(1) carbamylation under inflammatory conditions and the effects that this m

Background: As 13-valent pneumococcal conjugate vaccine (PCV13) is introduced, children who began vaccination with 7-valent pneumococcal conjugate vaccine (PCV7) may complete their vaccination with PCV13. This open-label phase 3 study evaluated immunogenicity and safety of PCV13 in Swedish infants and toddlers previously given 1 or 2 doses of PCV7 during infancy. Methods: Healthy infants previousl

Moraxella catarrhalis is a respiratory tract pathogen commonly causing otitis media in children and acute exacerbations in patients suffering from chronic obstructive pulmonary disease. Cartilage oligomeric matrix protein (COMP) functions as a structural component in cartilage, as well as a regulator of complement activity. Importantly, COMP is detected in resident macrophages and monocytes, alveo

The generation of toxic oligomers during the aggregation of the amyloid-beta (A beta) peptide A beta 42 into amyloid fibrils and plaques has emerged as a central feature of the onset and progression of Alzheimer's disease, but the molecular pathways that control pathological aggregation have proved challenging to identify. Here, we use a combination of kinetic studies, selective radiolabeling expe

The MYC genes are the most frequently activated oncogenes in human tumors and are hence attractive therapeutic targets. MYCN amplification leads to poor clinical outcome in childhood neuroblastoma, yet strategies to modulate the function of MYCN do not exist. Here we show that 10058-F4, a characterized c-MYC/Max inhibitor, also targets the MYCN/Max interaction, leading to cell cycle arrest, apopto