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Uppsatsen uppför en historisk överblick över hur En dåres försvarstal lästs och belyser hur den kritiska diskursen förändrats. Förklaringsmodellen utgår från Bourdieus fältbegrepp vilket hjälper påvisa att positioneringar inte sker naturligt utan i relation till varandra såväl som till de rum som står och gjorts lediga på det så kallade fältet. Uppsatsen undersöker läsningars förhållningssätt till
Geomatics is a domain that has gained relevance and importance within the field of Architecture and the Built Environment. Typically, Geomatics education in Delft, Lund, Bochum, Leuven, and Zagreb was best characterised as lecture-based: traditional and relatively passive. This has changed fundamentally after March 2020. In this article, we analyse the development towards more active learning and
Human rights are the basis by which the dignity of the human being is guaranteed. This is especially important in the relationship between persons and governments, who on the one hand have great power in form of legislation over these persons, but on the other hand must ensure the protection of human rights. A problem may arise when these two opposing forces of the State collide,1 as the individua
The human pathogen Haemophilus influenzae causes respiratory tract infections and is commonly associated with prolonged carriage in patients with chronic obstructive pulmonary disease. Production of outer membrane vesicles (OMVs) is a ubiquitous phenomenon observed in Gram-negative bacteria including H. influenzae. OMVs play an important role in various interactions with the human host; from neutr
We present a detailed study of the large-scale shock front in Stephan’s Quintet, a by-product of past and ongoing interactions. Using integral-field spectroscopy from the new William Herschel Telescope Enhanced Area Velocity Explorer (WEAVE), recent 144 MHz observations from the LOFAR Two-metre Sky Survey, and archival data from the Very Large Array and JWST, we obtain new measurements of key shoc
This paper presents the observation of four-top-quark (tt¯ tt¯) production in proton-proton collisions at the LHC. The analysis is performed using an integrated luminosity of 140 fb - 1 at a centre-of-mass energy of 13 TeV collected using the ATLAS detector. Events containing two leptons with the same electric charge or at least three leptons (electrons or muons) are selected. Event kinematics are
BACKGROUND: Cerebrospinal fluid (CSF) clearance via the olfactory pathway is well-documented in animal models. However, results from in vivo human studies appear inconsistent. Studies using intrathecal (IT) Gadolinium-based contrast agents (GBCA) enhanced MRI showed minimal tracer pass-through from intracranial to extracranial olfactory regions such as the nasal mucosa. Conversely, human imaging s
Cytolysin A (ClyA) is a pore-forming protein from a strongly silenced gene in non-pathogenic Escherichia coli, including typical commensal isolates in the intestinal microbiome of healthy mammalian hosts. Upon overproduction, ClyA-expressing bacteria display a cytolytic phenotype. However, it remains unclear whether sublytic amounts of native ClyA play a role in commensal E. coli-host interactions
Since 1955, a form of diabetes in lean, young (BMI <18·5 kg/m2, age <30 years) individuals with a history suggestive of undernutrition from before birth and throughout childhood has been described in the literature. In 1985, WHO formally classified it as malnutrition-related diabetes, but subsequently removed the classification in 1999 over a disagreement as to whether undernutrition was a suffici
We present a new suite of edge ('Engineering Dwarfs at Galaxy formation's Edge') cosmological zoom simulations. The suite includes 15 radiation-hydrodynamical dwarf galaxies covering the ultrafaint to the dwarf irregular regime () to enable comparisons with observed scaling relations. Each object in the suite is evolved at high resolution () and includes stellar radiation, winds, and supernova fee
Atopic dermatitis (AD) is a common inflammatory skin disease that affects both children and adults, including a large number of adults of reproductive age. Several guidelines for the treatment of AD exist, yet specific recommendations for the treatment of pregnant or lactating women and for adults planning to have a child are often lacking. This position paper from the European Task force on Atopi
Genetic studies promise to provide insight into the molecular mechanisms underlying type 2 diabetes (T2D). Variants associated with T2D are often located in tissue-specific enhancer clusters or super-enhancers. So far, such domains have been defined through clustering of enhancers in linear genome maps rather than in three-dimensional (3D) space. Furthermore, their target genes are often unknown.
The plasma proteins alpha1-microglobulin (alpha1-m) and bikunin are synthesized in the liver as a common precursor which is cleaved just before secretion. Half of plasma alpha1-m is covalently linked to fibronectin and alpha1-inhibitor-3, and more than 95% of bikunin is part of pre-alpha-inhibitor, inter-alpha-inhibitor and related large molecules. Both alpha1-m and bikunin have been shown to be i
The Dynamic Collections project is an ongoing initiative pursued by the Visual Computing Lab ISTI-CNR in Italy and the Lund University Digital Archaeology Laboratory-DARKLab, Sweden. The aim of this project is to explore the possibilities offered by a deep, structured interaction with a large set of digital replicas of archeological artefacts. The project developed and deployed a web-based platfor
Melatonin is produced in the dark by the pineal gland and is a key regulator of circadian and seasonal rhythms. A low melatonin level was reported in individuals with autism spectrum disorders (ASD), but the underlying cause of this deficit was unknown. The ASMT gene, encoding the last enzyme of melatonin synthesis, is located on the pseudo-autosomal region 1 of the sex chromosomes, deleted in sev
Popular Abstract in Swedish Detta arbete behandlar regleringen av arbetsgivarens arbetsledningsrätt och arbetstagarens arbetsskyldighet i svensk, engelsk och tysk rätt i ljuset av arbetslivets ökade flexibilisering. Arbetslivets flexibilisering handlar om att öka anpassningsförmågan och rörligheten, och beskrivs ofta som övergången från den traditionella anställningen till atypiska anställningar. The general aim of this doctoral thesis is to study the legal regulation of the managerial prerogative and how it relates to the employee’s obligation to work in Swedish, English and German law in the light of the increasing flexibilisation of working life. The ongoing flexibilisation of working life is often described as an increase in adaptability and allocative flexibility, and as a shift from
The detailed pathways of photoactivity on ultrafast time scales are a topic of contemporary interest. Using a tabletop apparatus based on a laser plasma X-ray source and an array of cryogenic microcalorimeter X-ray detectors, we measured a transient X-ray absorption spectrum during the ferrioxalate photoreduction reaction. With these high-efficiency detectors, we observe the Fe K edge move to lowe
The scale, rate, and intensity of humans’ environmental impact has engendered broad discussion about how to find plausible pathways of development that hold the most promise for fostering a better future in the Anthropocene. However, the dominance of dystopian visions of irreversible environmental degradation and societal collapse, along with overly optimistic utopias and business-as-usual scenari
