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Background: Quantitative magnetic resonance imaging (MRI), e.g. relaxation parameter mapping, may be sensitive to structural and compositional tissue changes, and could potentially be used to non-invasively detect and monitor early meniscus degeneration related to knee osteoarthritis. Objective: To investigate MR relaxation times as potential biomarkers for meniscus degeneration through comparison

BACKGROUND: Itch is a common symptom in the general population. Affected individuals often do not seek medical consultation and rely on Internet searches to obtain information regarding their itch.OBJECTIVES: The aim of this study was to attain insights into common concerns of the general population regarding itch can by analysing itch-related Internet search behaviour.METHODS: Google AdWords Keyw

We explore the connections between stellar age, chemistry, and kinematics across a Galactocentric distance of 7.5 < R(kpc) < 9.0, using a sample of ~12 000 intermediate-mass (FGK) turn-offstars observed with the RAdial Velocity Experiment (RAVE) survey. The kinematics of this sample are determined using radial velocity measurements from RAVE, and parallax and proper motion measurements from the T

Importance: High gluten intake during childhood may confer risk of celiac disease. Objectives: To investigate if the amount of gluten intake is associated with celiac disease autoimmunity and celiac disease in genetically at-risk children. Design, Setting, and Participants: The participants in The Environmental Determinants of Diabetes in the Young (TEDDY), a prospective observational birth cohort

Avhandlingen undersöker betydelsen och funktionen av tårar i romersk politisk kultur under republiken och tidig kejsartid i olika historiska sammanhang, huvudsakligen sorg, tårar och i olika politiska sammanhang där auktoritet, makt och underkastelse utövades eller iscensattes. Detta görs genom studier av hur tårar skildras i olika genrer och författarskap i latinsk och grekisk litteratur. AllmäntThe thesis explores the meaning and function of tears in Roman political culture during the Republic and the Early Empire in various historical settings: mourning, the law court, and in different political contexts where power, authority, and subjection were expressed or exercised. This is carried through by reading representations of weeping in Greek and Latin literary works in different genres,

We analyze the channel capacity of multiple-input multiple-output (MIMO) systems in frequcncy selective channels, with channel knowledge at the transmitter side. An optimum transmission scheme uses Shannon's principle of waterfilling jointly in the frequency and the spatial domain. However, we show in this paper that the largest gain by using waterfilling resides in the spatial domain, and that th

Context The evidence that measurement of the common carotid intima-media thickness (CIMT) improves the risk scores in prediction of the absolute risk of cardiovascular events is inconsistent. Objective To determine whether common CIMT has added value in 10-year risk prediction of first-time myocardial infarctions or strokes, above that of the Framingham Risk Score. Data Sources Relevant studies we

Eosinophils natively inhabit the small intestine, but a functional role for them there has remained elusive. Here, we show that eosinophil-deficient mice were protected from induction of Th2-mediated peanut food allergy and anaphylaxis, and Th2 priming was restored by reconstitution with il4(+/+) or il4(-/-) eosinophils. Eosinophils controlled CD103(+) dendritic cell (DC) activation and migration

BACKGROUND: The major factors individually reported to be associated with an increased frequency of CDKN2A mutations are increased number of patients with melanoma in a family, early age at melanoma diagnosis, and family members with multiple primary melanomas (MPM) or pancreatic cancer. METHODS: These four features were examined in 385 families with > or =3 patients with melanoma pooled by 17 Gen

This special issue of The Mental Lexicon contains a number of papers presented at a symposium at the Center for Languages and Literature, Lund University, on December 10, 2009. The interdisciplinary meeting brought together researchers from linguistics, psychology, and neuroscience in order to discuss different approaches to studying the complexities surrounding the modelling of word semantics.

Malignant cells, like all actively growing cells, must maintain their telomeres, but genetic mechanisms responsible for telomere maintenance in tumors have only recently been discovered. In particular, mutations of the telomere binding proteins alpha thalassemia/mental retardation syndrome X-linked (ATRX) or death-domain associated protein (DAXX) have been shown to underlie a telomere maintenance

Background A randomised double-blind placebo-controlled phase II study was done to assess the efficacy of a prophylactic quadrivalent vaccine targeting the human papillomavirus (HPV) types associated with 70% of cervical cancers (types 16 and 18) and with 90% of genital warts (types 6 and 11). Methods 277 young women (mean age 20.2 years [SD 1.7]) were randomly assigned to quadrivalent HPV (20 μ g

Low-complexity VLSI (very large scale integration) architecture of the square root algorithm is proposed for MIMO (multiple-input multiple-output) detection. As a modification to the traditional QR triangular array based architecture, the proposed architecture significantly reduces the area and power consumption with virtually no performance or throughput degradation. The finite word length effect

We describe the synthesis and antibacterial properties of a novel antimicrobial peptidyl derivative, (2S)-2-(Nalpha-benzyloxycarbonyl-arginyl-leucylamido-1-[(E)-cinnamoylamido]-3-methylbutane, structurally based upon the inhibitory centre of the human cysteine protease inhibitor, cystatin C. The derivative, here called Cystapep 1, displayed antibacterial activity against several clinically importa

Simultaneous digital breast tomosynthesis (DBT) and mechanical imaging (MI) offer the potential to combine anatomic information from DBT with functional information from MI. This makes it possible to associate tissue stiffness with specific anatomic structures in the breast, a combination that can reduce false-positive findings by using the MI data to discriminate between ambiguous lesions in DBT.

In this paper we investigate the possibility of socially assistive robots (SARs) supporting diagnostic screening for peripartum depression (PPD) within the next five years. Through a HRI/socio-legal collaboration, we explore the gender norms within PPD in Sweden, to inform a gender-sensitive approach to designing SARs in such a setting, as well as governance implications. This is achieved through

Gene fusions have been discussed in the scientific literature since they were first detected in cancer cells in the early 1980s. There is currently no standardized way to denote the genes involved in fusions, but in the majority of publications the gene symbols in question are listed either separated by a hyphen (-) or by a forward slash (/). Both types of designation suffer from important shortco