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Three applications of virtual reality for brain injury rehabilitation of daily tasks

Part of the process of rehabilitation after a brain injury is the relearning of various daily tasks such as preparing food, managing finances, getting from one place to another and so forth. These tasks require learning on all levels from physical to cognitive. Remembering a PIN code for a bank card, for example, can become automatic and ‘in the fingers’ after much repetition. However, other tasks

Temperature-dependent electronic and vibrational structure of the 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide room-temperature ionic liquid surface: a study with XPS, UPS, MIES, and HREELS.

The near-surface structure of the room-temperature ionic liquid 1-ethyl-3-methylimidazolium bis(trifluoromethylsulfonyl)amide has been investigated as a function of temperature between 100 and 620 K. We used a combination of photoelectron spectroscopies (XPS and UPS), metastable induced electron spectroscopy (MIES), and high-resolution electron energy loss spectroscopy (HREELS). The valence band a

3D analysis and grading of calcifications from ex vivo human meniscus

Objective: Meniscal calcifications are associated with the pathogenesis of knee osteoarthritis (OA). We propose a micro-computed tomography (μCT) based 3D analysis of meniscal calcifications ex vivo, including a new grading system. Method: Human medial and lateral menisci were obtained from 10 patients having total knee replacement for medial compartment OA and 10 deceased donors without knee OA (

A cloud-based resource for genome coordinate-based exploration and large-scale analysis of chromosome aberrations and gene fusions in cancer

Cytogenetic analysis provides important information on the genetic mechanisms of cancer. The Mitelman Database of Chromosome Aberrations and Gene Fusions in Cancer (Mitelman DB) is the largest catalog of acquired chromosome aberrations, presently comprising >70 000 cases across multiple cancer types. Although this resource has enabled the identification of chromosome abnormalities leading to speci

IDENTIFYING SUITABLE LOCATIONS FOR MANGROVE PLANTATION USING GEOSPATIAL INFORMATION SYSTEM AND REMOTE SENSING

Mangroves provide numerous environmental benefits, such as carbon sequestration, water purification, climate change mitigation, and flood and Tsunami impact reduction. Despite these unique advantages, mangroves are threatened by the combined adverse impacts of human activities and climate change. Therefore, it is essential to implement reasonable practices to avoid further degradation of mangroves

Galectin-8 Downmodulates TLR4 Activation and Impairs Bacterial Clearance in a Mouse Model of Pseudomonas aeruginosa Keratitis

Pseudomonas aeruginosa provokes a painful, sight-threatening corneal infection. It progresses rapidly and is difficult to treat. In this study, using a mouse model of P. aeruginosa keratitis, we demonstrate the importance of a carbohydrate-binding protein, galectin-8 (Gal-8), in regulation of the innate immune response. First, using two distinct strains of P. aeruginosa, we established that Gal-8−

Standardization of Antigen-Emulsion Preparations for the Induction of Autoimmune Disease Models

Autoimmune murine disease models are vital tools for identifying novel targets and finding better treatments for human diseases. Complete Freund’s adjuvant is commonly used to induce disease in autoimmune models, and the quality of the adjuvant/autoantigen emulsion is of critical importance in determining reproducibility. We have established an emulsification method using a standard homogenizer an

Implant migration and functional outcome of Reverse Shoulder Lateralized Glenosphere Line Extension System : a study protocol for a randomized controlled trial

Background: Inferior scapular notching is a complication unique to reverse shoulder arthroplasty. The most efficient technique to avoid inferior scapular notching has been reported to be lateralization of the glenoid offset. This study aims to compare radiological and functional outcomes of the DELTA Xtend® Reverse Shoulder System Lateralized Glenosphere Line Extension (intervention group) with th

Multi-actor business models in the manufacturing industry. Exploring how first-tier suppliers transition towards circularity.

Adopting circular business models (CBM) represents a key lever for industry to address urgent global challenges. Prior research recognizes the need for systems thinking and collaboration, but existing CBM tools and methods often implicitly assume that the focal firm has direct access to end customers, usage data and end-of-life phases. However, upstream suppliers who lack this access often produce

Clinical Isolates of Acinetobacter spp. Are Highly Serum Resistant Despite Efficient Recognition by the Complement System

Gram-negative bacteria from the genus Acinetobacter are responsible for life-threating hospital-related infections such as pneumonia, septicemia, and meningitis, especially in immunocompromised patients. Worryingly, Acinetobacter have become multi- and extensively drug resistant (MDR/XDR) over the last few decades. The complement system is the first line of defense against microbes, thus it is hig

Factor D Inhibition Blocks Complement Activation Induced by Mutant Factor B Associated With Atypical Hemolytic Uremic Syndrome and Membranoproliferative Glomerulonephritis

Complement factor B (FB) mutant variants are associated with excessive complement activation in kidney diseases such as atypical hemolytic uremic syndrome (aHUS), C3 glomerulopathy and membranoproliferative glomerulonephritis (MPGN). Patients with aHUS are currently treated with eculizumab while there is no specific treatment for other complement-mediated renal diseases. In this study the phenotyp

Role of HAMLET and metabolism in treatment and pathogenesis of pneumococci

Antimicrobial resistance (AMR) is one of the principle public health problems in the 21st century, threatening the available treatment strategies for bacterial infections. Here, we present a human protein-lipid complex, HAMLET (human alpha-lactalbumin made lethal to tumor cells) purified from human milk as a potential therapeutic agent which has both tumoricidal and bactericidal activity. HAMLET’s

Postoperative prognosis in craniopharyngioma with respect to cardiovascular mortality, survival, and tumor recurrence

Specific causes of death, survival, and recurrence rates were assessed in a cohort of 60 patients who had undergone surgery for craniopharyngioma between 1951 and 1988. Compared to the general population, the standardized mortality ratio (SMR) was increased [5.55; 95% confidence interval (CI), 3.68-8.22], and it was higher among females (SMR, 11.4) than males (SMR, 4.79). The risk of cardio- and c

Limitations on interest deductions: does BEPS action 4 presume tax avoidance?

Debt and equity are in most countries treated differently for taxing purposes. The asymmetry between the financing forms are being taken advantage of by MNEs, allowing them to plan their cross-border activities in a way that lowers the taxable burden for the whole group. To prevent the increasing problem of base erosion and profit shifting, Member States have implemented different rules limiting i

Manligt umgänge till salu: En artikelstudie om manlig heterosexuell och homosexuell prostitution mellan åren1993–2013

Uppsatsens syfte är att studera manlig prostitution så som den framträder i svensk dagspress mellan åren 1993-2013 och därvid jämföra manlig heterosexuell respektive homosexuell prostitution. De frågeställningar som undersöks är vilken bild som framträder för dessa grupper, vilka likheter och skillnader som finns mellan dem samt vilken förklaring Connell och Hirdmans genusteori skulle ge till dessPurpose of this thesis is to study male prostitution as it emerges in Swedish newspapers between the years 1993-2013 , comparing male heterosexual and homosexual prostitution. The issues examined is the picture that emerges for these groups , what similarities and differences between them and what explanation Connell and Hird 's gender theory would give to these potential differences . To inve

Palestinagård – The law as a tool of resistance or oppression?

During the fall of 2023, the Palestine solidarity movement grew as a response to Israel’s war on Gaza. The student movement for Palestine was an important part of the Palestine solidarity movement. Palestinagård demanded LU to comply with their demands: to stand in solidarity with Palestine and Israel’s systemic destruction of the education system (scholasticide), cut ties with complicit academic

Assessing the Potential of a New Building Material in Bhutan in relation to Energy-efficiency and Social Aspects

This study explores the potential of new building insulation material specifically wood wool in Bhutanese Buildings. To cover social and performance-related aspects a quantitative and semi-structured qualitative interview study about the perception of current construction quality and methods and new building materials was conducted as well as a simulation study with different renovation scenarios.

Metabolite Profiles of Heart Failure, Central Hemodynamic Derangement, and Response to Heart Transplantation

BACKGROUND: Heart failure (HF) is characterized by hemodynamic derangements that are likely to mediate systemic metabolic perturbations but limited data are available. Plasma metabolite profiling provides opportunities for comprehensive investigation of such perturbations. Here, we aimed to characterize plasma profiles that associate with HF and their relationship with central hemodynamics, sympto