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Usefulness of Serum B-Type Natriuretic Peptide Levels in Comatose Patients Resuscitated from Out-of-Hospital Cardiac Arrest to Predict Outcome

N-terminal pro-B-type natriuretic (NT-proBNP) is expressed in the heart and brain, and serum levels are elevated in acute heart and brain diseases. We aimed to assess the possible association between serum levels and neurological outcome and death in comatose patients resuscitated from out-of-hospital cardiac arrest (OHCA). Of the 939 comatose OHCA patients enrolled and randomized in the Targeted

Decreasing energy use of industrially produced multi family dwellings in Sweden

Building as many houses as possible in a factory environment seems like an effective way to systematically reduce productivity costs and improve quality in the building process. Based on this idea, a Swedish company has manufactured modules consisting of one or several rooms that were transported and assembled into multi family dwellings onsite. This paper analyses different improvements regarding

Episome profiles and mobilizable beta-lactamase plasmid in Haemophilus ducreyi

Chancroid caused by Haemophilus ducreyi has been described as a significantly predisposing factor of HIV heterosexual transmission in an endemic region of both diseases. The fastidious, H. ducreyi has been reported world wide with various antimicrobial susceptibility patterns. A high tendency of drug resistances has generally been found among isolates derived in Thailand. In this study, the plasmi

Differential proteomic analysis of HT29 Cl.16E cells line and intestinal epithelial cells by LC ESI/QTOF mass spectrometry.

Abstract in UndeterminedIntestinal epithelial cells (IECs) play a key role in Crohn's disease, a chronic inflammatory bowel disease which requires invasive examinations to be diagnosed. The comparison of the cellular protein expression profiles of Crohn's disease patients and healthy subjects is fundamental for the identification of proteins clinically relevant as new biomarkers or as drug targets

Immunohistochemical detection of cysteine-rich secretory protein 3 in tissue and in serum from men with cancer or benign enlargement of the prostate gland.

BACKGROUND. Recently, the gene for cysteine-rich secretory protein 3 (CRISP-3) was reported to be highly upregulated in prostate cancer (PCa) compared to benign prostatic tissue. The current aims were to investigate diagnostic use of tissue expression and immunodetection in serum of CRISP-3 for detection or monitoring of PCa. METHODS. Radical prostatectomy specimens and tissue microarrays from tra

The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I

Tapasin (Tpn) is an ER chaperone that is uniquely dedicated to MHC-I biosynthesis. It binds MHC-I molecules, integrates them into peptide-loading complexes, and exerts quality control of the bound peptides; only when an "optimal peptide" is bound will the MHC-I be released and exported to the cell surface for presentation to T cells. The exact mechanisms of Tpn quality control and the criteria for

Partial melting of diverse crustal sources - Constraints from Sr-Nd-O isotope compositions of quartz diorite-granodiorite-leucogranite associations (Kaoko Belt, Namibia)

The Torrabaai-Koigabmond Complex (southern Kaoko Belt, Namibia) consists of three main intrusive rock types including metaluminous hornblende- and titanite-bearing quartz diorites, metaluminous hornblende- and biotite-bearing granodiorites and peraluminous garnet- and muscovite-bearing leucogranites. Uranium-Pb zircon data obtained on the granodiorites and leucogranites indicate concordia upper in

The Humane School

My diploma project is a design proposal for a Rudolf Steiner School in Sirende, a village 12 km outside Kitale Town, Kenya. On Initiative taken by the anthroposophical association Föreningen Sofia in Sweden, a Steiner school opened in Sirende in year 2008. Today the school is in a very bad condition with over crowded classrooms and poor sanitary conditions. The need for a new school building is ur

Leveraging brand co-creation in a digital era: An IKEA case study

Purpose: The purpose is to examine how IKEA works with customer brand co-creation and how it can be further leveraged in the digital era. Methodology: This paper adopts a qualitative case study method, where the primary data consists of an interview with a Social Media Specialist with pre-existing knowledge of brand co-creation at IKEA in Sweden. Furthermore, research about IKEA and the ways they

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This thesis explores the name, naming and naming politics in three poetic texts which exhibit a concern with the normative force of language: Cristina Peri Rossi’s Evohé (1971), Julia Álvarez’ The Other Side/El otro lado (1995) and Ana Arzoumanian’s (2006) Juana I. In Evohé the woman-body and the woman-word collide and penetrate each other; in The Other Side/ El otro lado the English code conflict

Some theoretical and numerical aspects of the N-body problem

The N-body problem has been studied for many centuries and is still of interest in contemporary science. A lot of effort has gone into solving this problem but it's unlikely that a general solution will be found with the mathematical tools we have today. We review some of the progress that has been made over the centuries in solving it. We take a look at the first integrals, existence of solut

Underlåtenhet att avslöja våldtäkt - En åskådares skyldighet att agera eller en möjlighet att undkomma ansvar?

Bestämmelsen om underlåtenhet att avslöja våldtäkt har sällan åberopats i praktiken. Under 2017 prövades brottet av Högsta domstolen vars dom har tolkats i ett annat våldtäktsmål. Uppsatsens huvudsakliga syfte är att analysera de objektiva förutsättningarna för straffbarhet för åskådare vid underlåtenhet att avslöja våldtäkt samt analysera hur bestämmelsen tillämpas i praktiken. Med det avses såväThe provision regarding failure to reveal an ongoing rape has seldom been invoked in court. However, the crime was tried by the Swedish Supreme Court in 2017 and the judgment has been interpreted in another case of rape. The main purpose of the essay is to analyze the objective prerequisites for criminal responsibility regarding spectators in the event of failure to reveal an ongoing rape. This en

Population differences in the structure and coloration of great tit contour feathers

Contour feathers cover most of the avian body and play critical roles in insulation, social communication, aerodynamics, and water repellency. Feather production is costly and the development of the optimum characteristics for each function may be constrained by limited resources or time, and possibly also lead to trade-offs among the different characteristics. Populations exposed to different env

A Metalloproteinase Mirolysin of Tannerella forsythia Inhibits All Pathways of the Complement System.

Recent reports focusing on virulence factors of periodontal pathogens implicated proteinases as major determinants of remarkable pathogenicity of these species, with special emphasis on their capacity to modulate complement activity. In particular, bacteria-mediated cleavage of C5 and subsequent release of C5a seems to be an important phenomenon in the manipulation of the local inflammatory respon