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The growing interest and practice in outer space activities is the cause of a developing and more various space industry. The implication of an increasing human presence in outer space, as a result of such a development, is questioned in this study through an analysis of extraterrestrial mining. Three leading actors’ business-plans in the industry of extraterrestrial mining are examined, with the
This thesis investigates whether the implementation of a withholding tax on financial transactions obtained by the provision of certain digital services could solve the current problem of missing taxation rights regarding the income of highly digitalized multinational business models. Furthermore, the thesis aims to determine whether such tax could be in line with European Union law and the model
My diploma project is a design proposal for a Rudolf Steiner School in Sirende, a village 12 km outside Kitale Town, Kenya. On Initiative taken by the anthroposophical association Föreningen Sofia in Sweden, a Steiner school opened in Sirende in year 2008. Today the school is in a very bad condition with over crowded classrooms and poor sanitary conditions. The need for a new school building is ur
Popular Abstract in Swedish Diabetes kännetecknas av förhöjda halter av glukos i blodet och flera vanliga former förekommer. Typ 1 (T1D) diabetes är vanligast förekommande hos barnoch ungdomar och karakteriseras av att de insulin producerande cellerna (s.k. betacellerna) förstörs av kroppens eget immunförsvar, en autoimmun reaktion. Patienter med T1D diabetes kräver insulin för överlevnad och har T1D is most common in children and young adults and is characterized by autoimmune destruction of insulin producing pancreatic beta cells, presence of certain risk genotypes such as HLA-DQB1, INS VNTR, PTPN22 and need of insulin for survival. In adults the same situation is often referred to as Latent Autoimmune Diabetes in Adults (LADA), with age at onset after 35 years and non-insulin requiring
CK2, an acronym derived from the misnomer "casein kinase 2", denotes a ubiquitous and extremely pleiotropic Ser/Thr protein kinase, the holoenzyme of which is composed of two catalytic (alpha and/or alpha') and two noncatalytic beta subunits acting as a docking platform and the multifarious functions of which are still incompletely understood. By combining affinity chromatography and mass spectrom
BACKGROUND. Androgen deprivation is the only effective systemic therapy available for patients with prostatic carcinoma, but is associated with a gradual transition to a hormone-refractory prostate cancer (HRCAP) in which ligand-independent activation of the androgen receptor has been implicated. The beta(2)-adrenergic receptor (beta(2)-AR) is a well-known activator of the androgen receptor. METHO
The complement system is fundamental to both innate and adaptive immunity and can be initiated via the classical, lectin or alternative pathways. Cleavage of C4 by MASP-2, the initiating protease of the lectin pathway, is a crucial event in the activation of this pathway, preceding the eventual formation of the C3 convertase (C4bC2a) complex on the pathogen surface. Interactions required for the c
Here, monoolein-based nanoparticles (NPs), obtained through fragmentation of bulk liquid crystalline phases, and stabilized by two different emulsifiers, namely, Pluronic F127 (PF127) and lauroylcholine chloride (LCh), are investigated for structural features and for short-term in vitro cytotoxicity. Depending on the emulsifiers, different morphologies of the lipid NPs (cubosomes and liposomes) ar
Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic inflammation of the peripheral joints that eventually leads to cartilage destruction and bone erosion. The causes of RA remain largely unknown, but considerable evidence suggests a multifactorial aetiology involving both environmental and genetic factors. Large efforts have been directed towards the understanding of the mo
Introduction: Multidrug resistance (MDR) has been identified in wound bacterial isolates from Ukrainian war victims treated in Ukraine and across Europe. ILP100, a drug candidate for the treatment of skin wounds, is composed of a Limosilactobacillus reuteri expressing human chemokine CXCL12. In this study, the antimicrobial effects of ILP100 were tested on MDR bacteria isolated from wounds of Ukra
Title Reference tool for perceived quality ? within the Sony Ericsson Product Business Unit Accessories Organization. Author Jakob Frey-Skött Supervisors Annika Olsson, Department of Design Sciences, Division of Packaging Logistics, Lund Institute of Technology, Lund University. Gunilla Wejfeldt, Head of Quality Assurance, Sony Ericsson Product Business Unit Accessories Organization. Problem
Popular Abstract in Swedish I sökandet efter den rådande fostrings- och disciplineringsdiskursen i svensk skola åren 1947-1956 har Michel Foucaults diskursanalys utgjort en central utgångspunkt i denna avhandling. Jag har inledningsvis redogjort för modernitetens genombrott i Sverige och kort belyst befolkning och utbildning vid mitten av 1900-talet. Skolan som disciplineringsinstitution har beskThe purpose of this monograph is to discern what constituted the dominant fostering and discipline discourse in Swedish compulsory schools during the period 1947-1956. For this purpose Michel Foucault's discourse analysis has played a central role in this thesis. As a starting point, an account of the emergence of modernity in Sweden is given, as well as a brief presentation of the Swedish populat
This study considers the spread, character and development of the Swedish Enlightenment from the early Age of Liberty to the late Karl lohan period. This is done in six case studies three of them biographical and three of them of a more general character partly concerned with the history of concepts; all six case studies touch on the writers' world in the period. Chapter 1, "Dawn", discusses, aft
In 2010, Spence and Van Gelder presented a family of CNF formulas based on combinatorial block designs. They showed empirically that this construction yielded small instances that were orders of magnitude harder for state-of-the-art SAT solvers than other benchmarks of comparable size, but left open the problem of proving theoretical lower bounds. We establish that these formulas are exponentially
Stapylococcus aureus is a common infectious agent in e.g. sepsis, associated with both high mortality rates and severe long-term effects. The cytolytic protein α-hemolysin has repeatedly been shown to enhance the virulence of S. aureus. Combined with an unhindered spread of multi drug-resistant strains, this has triggered research into novel anti virulence (i.e. anti α-hemolysin) drugs. Their func
To date, few studies have investigated the simultaneous effects of macro-scale parameters (MSPs) such as land use, population density, geology, and erosion layers on micro-scale water quality variables (MSWQVs). This research focused on an evaluation of the relationship between MSPs and MSWQVs in the Siminehrood River Basin, Iran. In addition, we investigated the importance of water particle trave
