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Evacuation models of the future: Insights from an online survey on user’s experiences and needs

This paper presents a summary analysis of data regarding evacuation model users experiences and needs obtained via an online survey. The survey was available in 6 languages: English, German, Chinese, Spanish, Italian and Russian. The different versions allowed the survey to be accessible to an international participant base. The survey was developed by the team at www.Evacmod.net ; an evacuation m

Preparation of the Gaia Data Processing: First Astrometric Results

The Gaia mission of the European Space Agency (ESA) will produce high-precision astrometry for 10^9 objects up to 20th magnitude. The volume of data generated (about 150TB of compressed raw data) and the complexity of the relationships between them make the scientific processing a challenging task. This paper presents the basic concepts of the core of the astrometric data reduction, the AGIS syste

Reduced ROS production triggers arthritis / The role of T cells in arthritis pathogenesis

Popular Abstract in Swedish Brist på fria radikaler kan ge artrit Fagocytiska celler i vårt immunförsvar producerar fria syre-radikaler för att eliminera fagocyterade (uppätna) mikroorganismer. Produktionen av dessa syre-radikaler sker med hjälp av ett enzymkomplex (NADPH oxidas) i cellmembranet samt i membranet på de fagosomer, innehållande mikroorganismer, som bildas i och med fagocytos. MännisThe aim of this thesis is to defend a novel mechanism that triggers arthritis susceptibility in both rats and mice through reduced production of reactive oxygen species (ROS), but also to introduce a novel model for chronic relapsing arthritis. Five papers are included, all of which employ animal models for rheumatoid arthritis and one that also uses animal models for multiple sclerosis. Paper I a

Studies of time-resolved harmonic generation in intense laser fields in xenon

We report preliminary experimental and computational studies of the temporal evolution of the harmonics, generated in xenon, by 50-ps pulses from a Nd: YLF laser, amplified in Nd: glass amplifiers, and focused to produce intensities in the range 1013--5 {\texttimes} 1013 W cm{\textminus}2. Measurements were made of the temporal profiles of the seventh- and ninth-order harmonics using a specially m

The Challenge of Gender Bias in the IT Industry

Contextual Analysis through inquiries into Contextual Dependency is a way to specify and discuss more general issues of unequal distribution of power overall and the importance of gender issues as a specific example. This gives an Information Systems analyst an opportunity to ask some important questions. The sense making activities involved includes efforts to 'visualise' and communicate individu

Non-LTE calculations of radiative forces for thallium in the atmospheres of HgMn stars

Recent observations by the Goddard High-Resolution Spectrograph on the Rubble Space Telescope have dramatically improved our knowledge of the abundance of the heaviest elements in Mercury-Manganese (HgMn) stars (c.f. Leckrone et al. 1992 and Wahlgren et al. 1995). Explaining the observed abundance and isotope anomalies requires improved calculations of radiatively driven diffusion. We briefly revi

Tongue retraction is not so useful after all

This article reports model experiments where vocal tract profiles of high and mid unrounded front and high rounded back vowels were systematically modified to simulate small constriction shifts along the hard or soft palate, in order to test A. M. Bell's century-old proposal that small shifts of tongue arch fronting or retraction would yield audible shifts of vowel timbre. Such differences were cl

Permanent atrial fibrillation in patients without structural heart disease is not associated with signs of infection by Chlamydia pneumoniae and Helicobacter pylori.

OBJECTIVE: The objective of this study was to explore the role of Chlamydia pneumoniae and Helicobacter pylori infections in patients with idiopathic permanent atrial fibrillation. METHODS AND RESULTS: Sera from 72 patients with permanent atrial fibrillation without structural heart disease (mean age 69.6 years, 23 women) were analysed for IgG antibodies against Chlamydia pneumoniae and Helicobact

Particle generation from humans - a method for experimental studie in cleanroom technology

Particle generation from humans is a severe problem when working in cleanrooms and other controlled environments. Data regarding the number of particles generated by humans are few and there are no detailed references as to how these studies have been performed. An experimental method to determine the particle release from a human being in a cleanroom was developed and used to describe the variati

Survival benefit of lung transplantation in individuals with severe α(1)-anti-trypsin deficiency (PiZZ) and emphysema.

BACKGROUND: The objective of lung transplantation (LTx) is to prolong life, but the survival benefit for patients with severe α(1)-anti-trypsin deficiency (PiZZ) and emphysema is still unclear. The aim of this study was to assess whether PiZZ patients who have undergone lung transplantation (the lung transplant group, TxG) do better than patients who have continued on the usual medical therapy (th

Deletion of nemo-like kinase in T cells reduces single-positive CD8+thymocyte population

The β-catenin/Wnt signaling pathway plays an important role in all stages of T cell development. Nemo-like kinase (NLK) is an evolutionary conserved serine/threonine kinase and a negative regulator of the Wnt signaling pathway. NLK can directly phosphorylate histone deacetylase 1 (HDAC1), as well as T cell factor/lymphoid enhancer-binding factor (TCF/LEF), causing subsequent repression of target g

Simultaneous X-ray absorption and two-photon LIF for imaging the spray formation region

Imaging the spray formation region of atomizing sprays is particularly challenging due to the presence of a variety of irregular liquid structures such as ligaments, liquid blobs, droplets, liquid sheets and a possible liquid core. The number and concentration of those liquid bodies dictate the presence of liquid/air interfaces, which are responsible to undesired scattering effects. The resulting

THE EUROSDR GEOBIM PROJECT - DEVELOPING CASE STUDIES for the USE of GEOBIM in PRACTICE

Although the use of location-based data (location coupled with semantic information) within Geographical Information Systems (GIS) and from Earth Observation (e.g. satellite) sources has been long established for decision makers, this has only recently been reflected in the construction sector with a more recent move from Computer Aided Design (CAD) to Building Information Modelling. BIM has opene

Assessment of terrorism risk mitigation measures for iconic bridges

This paper describes the assessment of the cost efficiency of risk mitigation measures for terrorist attacks with Improvised Explosive Devices (IEDs) for an iconic bridge structure. The assessment is performed with a decision theoretical framework building upon very recent advances in the framework of the COST Action TU1402 on Quantifying the Value of Structural Heath Monitoring. The decision scen

Probabilistic fatigue crack growth modeling for reliability-based inspection planning

The fatigue deterioration modeling for welded steel structures subjected to high cycle fatigue is presented in the current document. The aim of this paper is to formulate approaches based on actual research results for the phases fatigue crack initiation, fatigue propagation and fatigue failure. The physical characteristics of the approaches are discussed in combination with the associated uncerta