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BACKGROUND: Animal agriculture has been criticised in terms of its sustainability from several perspectives. Ruminants such as dairy cows can transform inedible, low-quality protein in roughage and by-products from the food industry into the high-quality protein found in milk and meat. Evaluation of the protein conversion efficiency of dairy production from a sustainability and resource perspectiv
Coeliac disease (CD) is becoming a model for understanding the pathogenesis of autoimmune disorders. In CD, antibodies against transglutaminase 2 (TG2) and specific residues of gliadins have been identified. A similar situation is seen in rheumatoid arthritis (RA) with both anti-citrullinated protein antibodies (ACPA) and auto-antibodies against the citrullinating enzyme, peptidylarginine deiminas
Objective: The minor G allele of FOXO3A rs2802292 has been associated with longevity. We aimed to investigate whether a phenotype related to healthy metabolic aging could be identified in individuals carrying the longevity-associated FOXO3A rs2802292 G allele. Research Design and Methods: rs2802292 was genotyped in a phenotypically well-characterized population of young and elderly twins (n = 190)
Context: Arginine vasopressin (AVP) is known to affect liver glycogenolysis, insulin, and glucagon secretion and pituitary ACTH release. We previously showed that high copeptin, the stable C-terminal fragment of AVP prohormone, is independently associated with hyperinsulinemia and future development of diabetes mellitus. Objective: The objective of the study was to examine whether plasma copeptin
Adaptive tracking of non-linear dynamic plants is currently an important area of research. The main difficulty being felt by the research community is the lack of a general modelling framework that can facilitate synthesis of a simplistic control law while being capable of providing accurate approximation of non-linear systems. In this study a novel technique based on the control-oriented U-model
Hibernomas are benign tumors with morphological features resembling brown fat. They consistently display cytogenetic rearrangements, typically translocations, involving chromosome band 11q13. Here we demonstrate that these aberrations are associated with concomitant deletions of AIP and MEN1, tumor suppressor genes that are located 3 Mb apart and that underlie the hereditary syndromes pituitary ad
This article explores four preselected permanent magnet synchronous machine (PMSM) topologies suitable for direct mounting on low pressure spool in a turbo fan engine. The challenge of contributing to More Electric Engine (MEE) development is that the electrical machine needs to operate over wide speed range, take advantage of available space that forces to use a high number of poles and last but
Purpose: This study investigates the association between mean arterial pressure (MAP) and renal function after out-of-hospital cardiac arrest (OHCA). Materials and methods: Post-hoc analysis of 851 comatose OHCA-patients surviving >48 h included in the targeted temperature management (TTM)-trial. Results: Patients were stratified by mean MAP during TTM in the following groups; <70 mmHg (22%), 70–8
Atherosclerosis is a chronic inflammatory disease characterized by the entrapment of apolipoprotein B– containing lipoproteins in the arterial intima, leading to local inflammation. T helper (Th) cell 1–mediated immune responses have been associated with atherosclerosis, and the cytokine interleukin-25 (IL-25 or IL-17E) has been reported to potentially regulate Th1 cell– and Th17 cell–related immu
This study explores the nexus between financial inclusion and agricultural productivity in Tanzania, where agriculture is a key sector for the nation's economy and inclusive growth. Vulnerable to climate change, the sector faces productivity challenges due to rain anomalies and rising temperatures. Previous studies have highlighted financial inclusion as crucial for reducing vulnerability at t
Since we as architects have an influence on people‘s everyday routines in their homes, it is important to understand the most natural human needs in order to create spaces for a healthy and joyful life, which are strongly connected to the environment. The human body is a complex organism which is strongly influenced by its immediate surroundings, whilst responding with circadian rhythms to the eve
Purpose: The purpose of this study is to investigate the impact of brand logics on the success of brand extensions. Methodology: This study has examined two different case studies to better understand the effect of brand logic. An extensive literature review was done on “brand logics”, specifically Unique Selling Proposition (USP) and the Golden Circle, “brand extensions” as well as “brand identit
The role of food-producing sectors such as agriculture and aquaculture in the development process is debated and while some consider industrial production to be the answer, others suggest that small-scale production can also make contributions to poverty reduction and food security. This thesis aims to shed light on these relationships by performing quantitative analyses of the small-scale freshwa
Desalting technologies and fresh water production has been developed over the years, including primarily thermal and membrane processes. Five different types of desalination technology were studied and compared for long-term of use namely, thermal processes include multistage flash evaporation (MSF), multiple effect evaporation (ME), and vapor compression (VC) and membrane processes contain revers
Automation: Optimering av din tid Tänk dig att du har fått en deadline på ditt nya projekt. Ditt arbete för projektet beror helt på din praktiska noggrannhet och tidsoptimering, samtidigt så ska du lämna in massvis med pappersarbete. Du har en tuff tid framför dig ifall du ska klara detta på egen hand inom tidsramen. Här kommer automatisering in i bilden. Det noggranna och tidskrävande arbetet soAutomated information flow is an important way of optimizing the time used for analyzing processes. Other added benefits are that in a well-made automated system, the probability of human error diminishes because less liability is put on the person to manually transport and utilize the data. This notion of automation can be applied to the field of chromatography. This thesis investigates the poss
Context:A common genetic variant (rs10423928, A-allele) in the glucose-dependent insulinotropic polypeptide receptor gene (GIPR) is associated with decreased insulin secretion. Glucose-dependent insulinotropic polypeptide is secreted after food consumption and gipr knockout mice fed a high-fat diet are protected against obesity and disturbances in glucose homeostasis. Objective:Our objective was
The thesis starts with a description of the background to the change of the rules on deduction of VAT on mixed use immovable property through the insertion of Article 168a in the RVD. The reason according to the Amendment is to promote equity and to prevent unjustified cash-flow advantages granted to taxable persons who use acquire immovable property, deduct full input VAT and then pay it back o
The concept of actor capability outlines the basic features for the EU to be an international actor, separating it from nation-states and international organizations. This thesis applies this diagnostic concept to the case of EU-relations with the Democratic People’s Republic of Korea (DPRK). More specifically, it studies how the actor capability has changed by comparing the years 2001 and 2011 re
The study investigates how the consumption of bulk commodities has transformed from mundane to remarkable and reveals how people, events, meanings and ideas from the past have affected this change in consumers’ attitude. The paper discusses how mundane products have become a center of consumer interest and provides theoretical explanation of the phenomenon. The research focuses on bottled water as
