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Efficient screening of ligands interacting with G-protein-coupled receptors is central for modern drug development. Here, we describe an optimized reporter vector primarily intended for use in reporter cell lines expressing such receptors. The construct consists of a synthetic enhancer containing 9x TRE (12-O-tetradecanoylphorbol-13-acetate-responsive elements) fused to a minimal CMV (cytomegalovi

The lifetimes of three short-lived levels belonging to the 4f(9) 6p configuration and of two long-lived levels of the 4f(9) 5d configuration of Dy iii have been measured for the first time using time-resolved laser-induced fluorescence techniques. They are in good agreement with theoretical values calculated within the framework of a pseudo-relativistic configuration interaction approximation. Usi

PRR recognize conserved structures on pathogenic microbes and are important for the defense against invading microorganisms. However, accumulating evidence indicates that many pathogens have evolved mechanisms to avoid recognition by PRR. One type of PRR is the macrophage scavenger receptor A (SR-A), which has been shown to play an important role in recognition and non-opsonic phagocytosis of path

In developing countries such as Ethiopia, where chronic gastritis and peptic-ulcer disease are the most common endoscopic findings, it is important to study the association between Helicobacter pylori infection and gastroduodenal diseases. Both invasive and non-invasive diagnostic methods were therefore used to investigate 300, consecutive, adult patients with dyspepsia, from the gastrointestinal

The last mass-extinction event happened over 65 million years ago when an asteroid collided with earth, resulting in the loss of 76% of all species. Scientists now warn that we are on the precipice of a new mass-extinction, the responsibility of which can be placed entirely on one species, the homo sapiens. While some species of birds, bats, and arthropods are especially vulnerable, we are all int

Previous treatment studies have suggested an antidepressant effect of adjunctive probiotics, but more high-quality randomized controlled trials (RCTs) are needed before clinical implementation. The mechanisms underlying putative antidepressant effects of probiotics are not understood, but one possibility is that they are mediated via short-chain fatty acids (SCFAs) − neuroactive bacterial metaboli

Three different semiconductor nanowires are combined into a single optoelectronic artificial neuron. Our device provides a path towards low power computations with significantly reduced circuit footprint, thus addressing critical limitations in neuromorphic photonics. The false-coloured scanning electron micrograph shown in Figure 1a depicts the fabricated nanowire neuron. Two pin-doped InP nanowi

Photonics-based approaches to neuromorphic hardware offer advantages in speed and connectivity but often suffer from large device footprints.[1] Here, we present an ultra-compact artificial neuron built from semiconductor nanowires. A scanning electron micrograph of the nanowire device is presented in Figure 1a. Inside the dashed box, we show the neuron built from three III-V nanowires - two InP p

Accessible design enables participation in the digital society for everyone. However, cognitive accessibility is not well established within the field of web design. The International Classification of Functioning, Disability and Health (ICF) provides a descriptive framework that relates health conditions to functioning and participation. ICF Core Sets are purposefully tailored shortlists of ICF c

Gut-associated lymphoid tissues (GALT) represent major sites of adaptive immune priming in the intestine, yet our understanding of human GALT diversity and function remains limited. Here, we used single-cell RNA sequencing, flow cytometry, and confocal laser microscopy to map the fibroblast (FB) landscape of human GALT, including that of Peyer's patches (PP), mucosal isolated lymphoid follicles (M

Background:Aseptic loosening remains a main complication following total knee arthroplasty (TKA), requiring revision surgery. Radiostereometric analysis (RSA) can assess the risk of aseptic loosening. This study evaluated the migration and segmental motion of cemented and uncemented femoral and asymmetrical tibial Persona components (Zimmer Biomet) with model-based RSA.Methods:We conducted a rando

BACKGROUND: Recent research using a data-driven cluster approach has identified five discordant subclassifying body mass index (BMI) subgroups, characterized by cardiometabolic biomarkers deviated from those predicted by BMI.OBJECTIVE: This study aimed to investigate the associations of these subgroups with risks of metabolic dysfunction-associated steatotic liver disease (MASLD) and liver-related

Digitalization poses significant challenges to the EU VAT system, as it does in other areas of law. These challenges can be broadly divided into two main categories: those stemming from transformations in the economy, and those related to the legislative responses to these changes. In the VAT context, the first category includes the growing volume of transactions—particularly cross-border transact

In this chapter, I describe how technological progress triggers and shapes structural change within the economy and society, which in turn—if the resulting changes are significant enough—may shift the scope and outcome of established legislation and regulatory frameworks. The argument presented focuses on the ongoing digitalization, using its common technological characteristics to identify and de

Immune Profiling of Head and Neck cancers | Immunotechnology Skip to main content This site uses cookies to enhance the user experience. By continuing to use the site you agree that cookies are used according to our Cookie Policy (on the website of LTH) . Essential cookies These cookies are necessary for the website to function and cannot be turned off in our systems. These cookies do not store an

https://www.immun.lth.se/research/principal-investigators/malin-lindstedt/research/tumor-infiltrating-immune-cells-in-head-and-neck-cancer/immune-profiling-of-head-and-neck-cancers/ - 2026-05-02

2021 HT_LP2 FMSN60 CEQ Course evaluation ver 9.0 (2021-01-23) LTH Course evaluation report - CEQ, FMSN60 Basic facts Course name Financial Statistics Course code FMSN60 ECTS credits 7.5 hp Year 202122 Study period the course was finishedHT_LP2 Programme all Registrated students 32 Number answers and response rate 6 / 19 % Number answers from males 5 Number answers from females 0 Study hours accord

https://www.maths.lu.se/fileadmin/maths/utbildning_education/FMSN60_2021_HT_LP2_arbetsrapport_en.pdf - 2026-05-02

diss.dongguk.edu @dongguk_summer_2026 More Than Classes — It’s a Journey Through Dongguk! Discover Korean culture and society through lectures, cultural excursions with Dongguk. Learn, travel, and make memories that go beyond the classroom.ond the classrro Session 1 : June 22 ~ July 3 (2 weeks) Session 2 : July 6 ~ July 17 (2 weeks) aaaaaattttttt ttttttthhhhhhheeeeee cccccceeeeeennnnnnttttttteeeee

https://www.student.lth.se/fileadmin/lth/utbildning/studerautomlands/andra_filer/2026_DISS_E_BROCHURE.pdf - 2026-05-02

https://www.vetenskaphalsa.se/socker-kan-oka-risken-for-hjart-karlsjukdom/comment-page-1/ - 2026-05-02

Department of Construction Sciences Solid Mechanics ISRN LUTFD2/TFHF-14/5189-SE(1-71) Parameter study on nonlinear piping systems exposed to time history loading in ANSYS Master’s Dissertation by Stefan Alkmyr Supervisors: M.Sc. Jimmy Carlsson, ÅF-Industry AB Associate Professor Håkan Hallberg, Div. of Solid Mechanics Examiner: Associate Professor Mathias Wallin, Div. of Solid Mechanics Copyright

https://www.solid.lth.se/fileadmin/hallfasthetslara/utbildning/examensarbete/TFHF5189.pdf - 2026-05-02