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Identifying stars found in the Milky Way as having formed in situ or accreted can be a complex and uncertain undertaking. We use Gaia kinematics and APOGEE elemental abundances to select stars belonging to the Gaia-Sausage-Enceladus (GSE) and Sequoia accretion events. These samples are used to characterize the GSE and Sequoia population metallicity distribution functions, elemental abundance patte

Aims: The aim of this cross-sectional study was to examine the prevalence of the multidimensional phenomenon of fatigue in adults with congenital heart disease. Background: Adults with congenital heart disease are a growing population, and patient-reported outcomes can provide valuable information about the patient's experience of living with CHD. Fatigue is a multidimensional phenomenon that can

Behind everything we do in our daily lives there is a reason for doing it. This paper looks into the motives behind DDoS attacks as a form of cyberattack along with attacker personas. This paper also investigates DDoS attacks technically and it is suggested that there is a need for a socio-technical approach to these attacks to investigate why they occur and the reasoning the attacker(s) could hav

Malaria is a potentially life-threatening disease with approximately half of the world’s population at risk. Young children and pregnant women are hit hardest by the disease. B cells and antibodies are part of an adaptive immune response protecting individuals continuously exposed to the parasite. An infection with Plasmodium falciparum can cause dysregulation of B cell homeostasis, while antibodi

The frequency dependence of the permittivity, permeability, and index of refraction restrict metamaterial applications such as cloaking and perfect lenses. Here, the principles of causality and passivity together with identities for Herglotz functions are used to construct various sum rules. The sum rules relate the frequency dependence of the material parameters with their high- and low-frequency

BACKGROUND: Radiostereometric analysis (RSA) is a highly accurate tool to detect implant migration and predict loosening following total knee arthroplasty (TKA). However, little is known about the predisposing risk factors for implant migration, nor which migration profile should be considered physiological (i.e., merely part of an implant-settling phase) and which should be considered pathologica

Activism against sexual violence was one of the Egyptian Revolution’s most significant mobilising forces, but the country’s return to authoritarian rule has circumvented possibilities for organising and carrying out political resistance, including activism against sexual harassment. This article shows that despite this political oppression, young feminists continue to raise their voices and organi

Introduction: CD40 signaling activates dendritic cells leading to improved T cell priming against tumor antigens. CD40 agonism expands the tumor-specific T cell repertoire and has the potential to increase the fraction of patients that respond to established immunotherapies. Areas covered: This article reviews current as well as emerging CD40 agonist therapies with a focus on antibody-based therap

Regulated Delivery of Glial Cell Line-Derived Neurotrophic Factor into Rat Striatum, Using a Tetracycline-Dependent Lentiviral Vector HUMAN GENE THERAPY 15:934–944 (October 2004) © Mary Ann Liebert, Inc. Regulated Delivery of Glial Cell Line-Derived Neurotrophic Factor into Rat Striatum, Using a Tetracycline-Dependent Lentiviral Vector BILJANA GEORGIEVSKA,* JOHAN JAKOBSSON,* ELISABETH PERSSON, CEC

https://www.molecular-neurogenetics.lu.se/sites/molecular-neurogenetics.lu.se/files/publication_in_human_gene_therapy.pdf - 2026-05-03

A fundamental difference between ordinary and leisure time is for many the ability to indulge in extra-ordinary activities of both body and mind. Rooted in antiquity, the renaissance villas were often used as spaces for indulgence of artistic endeavors, be it philosophical discussions, poetry-writing or lavish parties. Of indulgence, Aristoteles wrote: ‘The self-indulgent man craves for all pleasa

The thesis covers human rights violations against persons with disabilities, focusing on their right to political life and the right to vote, using the framework of critical disability theory. The aim of the thesis is two-folded: it analyses the use of the UN Convention on the Rights of Persons with Disabilities (CRPD) in the adjudication of the European Court of Human Rights (ECtHR) with a focus

The thesis concentrates on the issue of bill of lading fraud and discusses legal remedies as to respective type of fraud. Due to complexity and difference of each jurisdiction, the thesis selects English law and Chinese law as targeted jurisdiction, under which the issue of bill of lading will be addressed and analyzed. In addition to domestic law, the recent-adopted international convention, name

Oath-taking during Roman Antiquity constitutes a telling example of how words and matter interplay and relate to one another. Ancient Latin literature provides a myriad of representations of oaths sworn, both fictive and supposedly historical, where matter somehow figure in the procedure. In this study, a selection of personal oaths from Roman literature are explored in terms of materiality and ag

The presence of viral immune triggers at the intestinal mucosa can have multipleglobal effects on intestinal integrity, including relative protection fromsubsequent inflammatory bowel disease. During the last century, the westernworld has achieved a remarkable success in preventing infectious diseases,which increased the general life expectancy dramatically. However, theincidence and prevalence of

A people-centred approach for designing large-scale built-up spaces necessitates systematic anticipation of user’s embodied visuo-locomotive experience from the viewpoint of human-environment interaction factors pertaining to aspects such as navigation, wayfinding, usability. In this context, we develop a behaviour-based visuo-locomotive complexity model that functions as a key correlate of cognit

Motivated by the need for realistic, dynamically self-consistent, evolving galaxy models that avoid the complexity of full, and zoom-in, cosmological simulations, we have developed Nexus, an integral framework to create and evolve synthetic galaxies made of collisionless and gaseous components. Nexus leverages the power of publicly available, tried-and-tested packages: the stellar-dynamics, action