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The voltage sensitive Lc-type Ca2+ channel is functionally coupled to the exocytotic machinery
Although N- and P-type Ca2+ channels predominant in fast-secreting systems, Lc-type Ca2+ channels (C-class) can play a similar role in certain secretory cells and synapses. For example, in retinal bipolar cells, Ca2+ entry through the Lc channels triggers ultrafast exocytosis, and in pancreatic beta-cells, evoked secretion is highly sensitive to Ca2+. These findings suggest that a rapidly release
Multicast routing for ad hoc networks with a multiclass scheme for quality of service
As multimedia- and group-oriented computing becomes increasingly popular for the users of wireless mobile networks, the importance of features like quality of service (QoS) and multicasting support grows. Ad hoc networks can provide users with the mobility they demand, if efficient QoS multicasting strategies are developed. The ad hoc QoS multicasting (AQM) protocol achieves multicasting efficienc
beta(1) integrins are not required for the maintenance of lymphocytes within intestinal epithelia.
b1 integrins are thought to play a central role in maintaining lymphocytes within mucosal epithelia via their interactions with extracellular matrix proteins and subepithelial cellular components within and underlying the basement membrane. In the current study type a (CD8abTCRab) and type b (CD8aaTCRcd and CD8aaTCRab) intraepithelial lymphocyte (IEL) subsets within the mouse small intestine were
Logarithmic phase Escherichia coli K1 efficiently avoids serum killing by promoting C4bp-mediated C3b and C4b degradation
Meningitis caused by Escherichia coli K1 is a serious illness in neonates with neurological sequelae in up to 50% of survivors. A high degree of bacteremia is required for E. coli K1 to cross the blood-brain barrier, which suggests that the bacterium must evade the host defence mechanisms and survive in the bloodstream. We previously showed that outer membrane protein A (OmpA) of E. coli binds C4b
HMG-CoAR is an Independent Predictor of Recurrence Free Survival in Epithelial Ovarian Cancer
Being good and being nice. Identity Work in Social Work
Within-host competition between Borrelia afzelii ospC strains in wild hosts as revealed by massively parallel amplicon sequencing.
Infections frequently consist of more than one strain of a given pathogen. Experiments have shown that co-infecting strains often compete, so that the infection intensity of each strain in mixed infections is lower than in single strain infections. Such within-host competition can have important epidemiological and evolutionary consequences. However, the extent of competition has rarely been inves
CD11b(+)Ly6C(++)Ly6G(-) cells show distinct function in mice with chronic inflammation or tumor burden
Background: S100A9 has been shown to be important for the function of so called Myeloid Derived Suppressor Cells (MDSC). Cells with a similar phenotype are also involved in pro-inflammatory processes, and we therefore wanted to investigate the gene expression and function of these cells in animals that were either subjected to chronic inflammation, or inoculated with tumors. Methods: CD11b(+)Ly6C(
Inter alpha inhibitor (I alpha I) inhibits classical complement pathway at C1 level
Bolagsstyrelsens sociala ansvar - Tar etiken vid där reglerna tar slut?
Urban geographic information systems : the city of Berkeley Pilot GIS
Of all information gathered and maintained by a small municipality, in this case the city of Berkeley, California, the percentage that is somehow geographically related is usually very high. The key to an efficient land management and analysis system is to link information gathered by a municipality's administration to its actual geographic locations; locations that together form the complexit
Blanket Retention of Electronic Communications Traffic Data and the Right to Respect for Private Life - Sweden in Focus
Detta examensarbete rör direktiv 2006/46/EG och dess överensstämmelse med den europeiska konventionen om skydd för de mänskliga rättigheterna och de grundläggande friheterna. Examensarbetet använder Sverige som ett exempel, och analyserar främst lagen (2003:389) om elektronisk kommunikation och dess tillkortakommanden vad gäller brottsbekämpande myndigheters tillgång till lagrade trafikuppgifter. This thesis concerns Directive 2006/46/EC and its compliance with the European Convention on Human Rights and Fundamental Freedoms. The thesis uses Sweden as an example, and mainly analyses the shortcomings in Swedish legislation on how traffic data may be accessed by law enforcement authorities, finding that the regulations under the Swedish Electronic Communications Act breaches Article 8 and 13
Överföringsproblematiken med ett styrinstrument – en fallstudie av Kemira Water
Syftet med vår studie är att undersöka de problem som kan uppstå vid en överföring av ett styrinstrument, innehållande Key Performance Indicators, från en organisation till en annan i samband med förvärv. Uppsatsen utgår från en fallstudie av ett företag i kemibranschen. I vår fallstudie använder vi ett abduktivt angreppssätt och en kvalitativ metod. I den teoretiska referensramen utgår vi ifrån t
UV and IR Absorption Cross-sections of HCHO, HCDO, and DCDO
UV (240-370 nm) and IR (3200-1500 cm-1) absorption cross-sections of HCHO, HCDO, and DCDO in abath gas of N2 at atmospheric pressure and 296 K are reported from simultaneous measurements in the twospectral regions. Cross-sections were placed on an absolute scale through quantitative conversion offormaldehyde to CO and HCOOH by titration with Br atoms, also monitored by FTIR. The integrated UVabsor
Understanding user participation in research on ageing and health – experiences and emerging findings from the UserAge program
On the coherence properties of FEL
FELs are well known for generating highly coherent light with excellent brilliance. In order to improve FEL coherence we have to follow how coherence evolves along the undulator and determine the factors that influence it the most. This paper presents qualitative coherence features that shine new light on the importance of coherence studies in the design of an FEL. By simulating and then analyzing
Chemical composition and in vitro starch digestibility of pigmented corn tortilla
BACKGROUND: Tortillas were prepared from two (blue and regular white) maize varieties and compared with regard to chemical composition and in vitro starch digestibility, i.e., available starch (AS), total (RS) and retrograde (RRS) resistant starch contents, amylolysis rate and predicted glycemic index (pGI). The impact of cold storage (4°C) on digestibility was also investigated. RESULTS: Despite
Subtilisin inhibitors in Canavalia and Vicia faba seeds. A comparative study
Subtilisin isoinhibitors (SI) were isolated from jack bean (Canavalia ensiformis L) and broad bean (Vicia faba L) seeds. Jack beans contain three isoinhibitors (pI 6.6, 6.3 and 6.0) that constitute 0.021 g per 100 g of dry seeds, while the two active proteins from broad beans (pI 5.7 and 5.1) represent 0.028%. The molecular weight, determined by gel filtration, is around 8000 D in both legumes. La
Linking lean to green – energy efficiency as a value stream
Over the past few decades, lean management philosophies have penetrated various sectors of industry. At same time, dynamic environmental, or green, management is needed to succeed in the current green conscious market. Some research has already been conducted on the potential synergy gains of the two management philosophies, since both are known to strive towards efficient use of resources, elimin
