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Dynamical orbital evolution scenarios of the wide-orbit eccentric planet HR 5183b

The recently discovered giant exoplanet HR5183b exists on a wide, highly eccentric orbit (a = 18 au, e = 0.84). Its host star possesses a common proper-motion companion which is likely on a bound orbit. In this paper, we explore scenarios for the excitation of the eccentricity of the planet in binary systems such as this, considering planet-planet scattering, Lidov-Kozai cycles from the binary act

Auditory hypersensitivity and attention in survivors of paediatric brain tumours

Objective: Both auditory and visual hypersensitivity are clinical features of mental fatigue after acquired brain damage or in neurological disorders. Both types of hypersensitivity are also associated with attention deficits, especially in neurodevelopmental syndromes. The aim of this study was to examine auditory and visual hypersensitivity, and associations to attention, in a group of children

Using binaries in Globular Clusters to catch sight of Intermediate-Mass Black Holes

The dynamical evolution of globular clusters (GCs) is tied to their binary population, as binaries segregate to the cluster centre, leading to an increased binary fraction in the core. This central overabundance of mainly hard binaries can serve as a source of energy for the cluster and has a significant effect on the observed kinematics, such as artificially increasing the observed line-of-sight

Cluster Formation Induced by Local Dielectric Saturation in Restricted Primitive Model Electrolytes

Experiments using the Surface Force Apparatus (SFA) have found anomalously long-ranged charge–charge underscreening in concentrated salt solutions. Meanwhile, theory and simulations have suggested ion clustering to be a possible origin of this behavior. The popular Restricted Primitive Model of electrolyte solutions, in which the solvent is represented by a uniform relative dielectric constant, εr

Oesophageal fluoroscopy in adults-when and why?

Oesophageal fluoroscopy is a radiological procedure that uses dynamic recording of the swallowing process to evaluate morphology and function simultaneously, a characteristic not found in other clinical tests. It enables a comprehensive evaluation of the entire upper gastrointestinal tract, from the oropharynx to oesophagogastric bolus transport. The number of fluoroscopies of the oesophagus and t

Maternal and Infant Health: Understanding the Role of Institutions and Medical Innovations

This chapter examines the development of maternal and infant mortality and its connection to changes in medical and healthcare treatment of mothers and infants in the city of Landskrona, Sweden, and its rural hinterland between 1905 and 2015. The authors show that maternal mortality, stillbirth rates, and infant mortality declined strongly in this period. In parallel, hospitals began to admit more

“Always a potent object”? : The Shifting Role of the Bible in Margaret Atwood’s Novels

The Bible appears regularly in Margaret Atwood’s novels, from The Edible Woman in 1969 to The Testaments in 2019. Atwood’s characters do not tend to be religious, but like most people in the Western world, they encounter the Bible in schools, at funerals, in headlines, advertisements, and occasionally from religious people themselves. Atwood’s Bible is a Christian Bible, the references running fro

Add-on pramipexole for anhedonic depression : study protocol for a randomised controlled trial and open-label follow-up in Lund, Sweden

INTRODUCTION: Many depressed patients do not achieve remission with available treatments. Anhedonia is a common residual symptom associated with treatment resistance as well as low function and quality of life. There are currently no specific and effective treatments for anhedonia. Some trials have shown that dopamine agonist pramipexole is efficacious for treating depression, but more data is nee

An ECG-based model to distinguish cardiac sarcoidosis from arrhythmogenic right ventricular cardiomyopathy

Arrhythmogenic right ventricular cardiomyopathy (ARVC) and cardiac sarcoidosis (CS) can show significant overlap in their clinical presentation. Differentiation between both is crucial for optimal patient management. Aim of this study is to develop an ECG-based machine learning model to distinguish between ARCV and CS patients. The study population included 100 patients (50 with ARCV and 50 with C

Predicting adverse cardiac events at the emergency department : A deep learning approach

The emergency department is a stressful environment, in which physicians are required to make fast and accurate diagnostic assessments amidst an ever increasing flood of clinical information, including a growing body of medical knowledge. Meanwhile, the digitization of medical health records in combination with recent breakthroughs in Artificial Intelligence is ushering in a new era of precision m

Blood levels of Mycobacterium tuberculosis (Mtb)antigen-triggered immune markers in people exposed to tuberculosis with regard to Mtb infection status and receipt of tuberculosis preventive therapy

Background: Interferon-γ release assays (IGRAs) for tuberculosis infection (TBI) cannot distinguish different stages of the TBI spectrum (including spontaneously cleared infection). We investigated patterns of Mtb-specific blood mediators in people with and without TBI during tuberculosis preventive therapy (TPT). Methods: Individuals with likelihood of recent Mtb exposure, aged 15–25 years, with