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HAMLET, a protein complex from human milk has bactericidal activity and enhances the activity of antibiotics against pathogenic Streptococci

HAMLET is a protein-lipid complex derived from human milk that was first described for its tumoricidal activity. Later studies showed that HAMLET also has direct bactericidal activity against select species of bacteria, with highest activity against Streptococcus pneumoniae Additionally, HAMLET in combination with various antimicrobial agents can make a broader range of antibiotic-resistant bacter

Swedish public and private housing companies’ access to the capital market for financing energy renovation

The financing of energy efficiency measures and renovations is key to reaching energy efficiency targets for the housing sector. The purpose of this article is to add the Swedish case of how capital market funds have become accessible and used by public and private housing companies, in particular for energy efficiency measures. The core of this article are interviews with representatives of Swedi

A Multilevel Circular Economy Repair Society Model: Understanding system-wide implications of normalized product repair from the perspective of the Product User

Initiatives to upscale repair activities are becoming increasingly common, with the latestbeing the EU commission’s proposal to strengthen consumers’ right to repair. However, theseinitiatives are not viewed comprehensively, particularly not for how they impact the product user’sexperience of the repair process, and what type of repair conditions would emerge once fullyimplemented. This gap exists

Choice awareness and manipulation blindness : A cognitive semiotic exploration of choice-making

Within cognitive science, “blindness” to choice is commonly treated as typical of human cognition, implying unreliable agents who essentially lack any awareness of their own choices (e.g. Johansson et al., 2005, 2008; Hall et al., 2010, 2013). Within cognitive semiotics, however, choice awareness is seen as a continuous phenomenon, which is susceptible to the influence of a variety of factors. Man

Inhalation and dermal uptake of particle and gas phase phthalates - A human chamber exposure study

We have exposed sixteen test subjects to particle and gas phase phthalates in the controlled chamber exposure study. Deuterium labelled phthalates were used to generate particle D4-DEHP (di(2-ethylhexyl) phthalate) and gas phase D4-DEP (diethyl phthalate) for exposures scenarios allowed studying the dermal only and combined inhalational and dermal uptake. Metabolites were measured in urine samples

Seasonally divided moult in the Barred Warbler (Sylvia nisoria) is an endogenously controlled strategy

The seasonal timing of moult in migratory birds is an adaptation to cope with time constraints in the annual cycle. Kiat and Izhaki analysed moult patterns in Palaearctic passerines and rejected the proposition that seasonally divided moult is an endogenously controlled strategy. Instead, they advocated the view that it occurs due to a flexible and opportunistic timing of moult. In contrast, we ar

Peritraumatic dissociation and chronic posttraumatic symptomatology : Thirty years and counting

Three decades ago, systematic research on possible acute and long-term aftereffects of peritraumatic dissociation (PD) was partly spurred by the proposal of a Brief Reactive Dissociative Disorder (BRDD) and the associated literature reviews and analyses of datasets (Cardeña, Lewis-Fernández, Beahr, Pakianathan & Spiegel, 1996; Cardeña et al., 1998; Spiegel & Cardeña, 1991). The goal was to

The spread of passengers on platforms and dwell times for commuter trains: A case study using automatic passenger count data

This study investigates how the spread of boarding passengers between the doors of a train affects the probability of dwell time delays for commuter trains. We make use of automatic passenger count data, collected on a door-by-door level, from commuter trains in the Southern region of Scania in Sweden. The aim of our study is to understand the context in which potential measures to spread out boar

Skin and wound delivery systems for antimicrobial peptides

Non-healing wounds cause hundreds of thousands of deaths every year, and result in large costs for society. A key reason for this is the prevalence of challenging bacterial infections, which may dramatically hinder wound healing. With resistance development among bacteria against antibiotics, this situation has deteriorated during the last couple of decades, pointing to an urgent need for new woun

The effects of Galactic model uncertainties on LISA observations of double neutron stars

Observations of binaries containing pairs of neutron stars using the upcoming space-based gravitational wave observatory, LISA, have the potential to improve our understanding of neutron star physics and binary evolution. In this work, we assess the effect of changing the model of the Milky Way’s kinematics and star formation history on predictions of the population of double neutron stars that wi

MOCCA-Survey Database: extra galactic globular clusters – III. The population of black holes in Milky Way and Andromeda-like galaxies

This work investigates the black hole (BH) population of globular clusters (GCs) in Milky Way- and Andromeda-like galaxies. We combine the population synthesis code MASinGa and the MOCCA-Survey Database I to infer the properties of GCs harbouring a stellar-mass BH subsystem (BHS), an intermediate-mass BH (IMBH), or neither of those. We find that the typical number of GCs with a BHS, an IMBH, or

Longitudinal change in cerebro-placental ratio (CPR) between 37 and 40 weeks of pregnancy is associated with non-reassuring fetal status and increased risk of cesarean section

Objective: To evaluate in low-risk pregnancies if longitudinal change in cerebro-placental ratio (CPR) between 37 and 40 weeks of pregnancy is associated with cesarean section (CS) for non-reassuring fetal status (NRFS) during labor. Methods: This is a prospective observational study of women with singleton low-risk pregnancies who underwent an ultrasound scan at 36 + 0 to 37 + 6 and 39 + 0 to 41

Fluorescence depolarization studies of heteroatom-doped CDs

In this work, we exploited time-resolved fluorescence polarization anisotropy (TRFA) to characterize un-doped and doped carbon dots (CDs). The rotational correlation time related to the size of the particle through classical Stokes-Einstein-Debye equation. The TRFA technique applied in this study achieves picoseconds time resolution, which approximately corresponds to the particle size determinati

A spatially explicit model of landscape pesticide exposure to bees : Development, exploration, and evaluation

Pesticides represent one of the greatest threats to bees and other beneficial insects in agricultural landscapes. Potential exposure is generated through compound- and crop-specific patterns of pesticide use over space and time and unique degradation behavior among compounds. Realized exposure develops through bees foraging from their nests across the spatiotemporal mosaic of floral resources and