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Disease-related variations of the glycosylation of haptoglobin in the dog

Haptoglobin phenotypes have been shown in human medicine to be related to the prevalence of various diseases. Furthermore, abnormal glycosylation of haptoglobin has been reported as a consequence of liver disease, cancer and immunological disorders in man. To our knowledge, similar findings have not, so far, been reported in canine disease. The present paper describes a method for investigation of

Collisions and close encounters involving massive main-sequence stars

We study close encounters involving massive main-sequence stars and the evolution of the exotic products of these encounters as common-envelope systems or possible hypernova progenitors. We show that parabolic encounters between low- and high-mass stars and between two high-mass stars with small periastrons result in mergers on time-scales of a few tens of stellar free-fall times (a few tens of ho

Development of high-grade lymphoma in Helicobacter pylori-infected C57BL/6mice

Helicobacter pylori infection is associated with chronic gastritis, peptic ulcer disease, gastric adenocarcinoma and MALT lymphoma. Mice with H. pylori infection develop severe gastritis and atrophic changes in their stomachs after 6 months. We followed H. pylori -infected animals for 13 months to find out whether dysplasia, carcinoma or lymphoma developed. Six-week-old C57BL/6 mice were infected

Red supergiants as potential Type IIn supernova progenitors: Spatially Resolved 4.6 Mum CO Emission Around VY CMa and Betelgeuse

We present high-resolution 4.6 mu m CO spectra of the circumstellar environments of two red supergiants (RSGs) that are potential supernova (SN) progenitors: Betelgeuse and VY Canis Majoris (VY CMa). Around Betelgeuse, (CO)-C-12 emission within +/-3 '' (+/-12 km s(-1)) follows a mildly clumpy but otherwise spherical shell, smaller than its similar to 55 '' shell in KI lambda 7699. In stark contras

Impact of urban water supply on energy use in China : a provincial and national comparison

To reduce greenhouse gas (GHG) emissions and help mitigate climate change, urban water systems need to be adapted so that electrical energy use is minimised. In this study, energy data from 2011 was used to quantify energy use in China’s urban water supply sector. The objective was to calculate the energy co-benefits of urban water conservation policies and compare energy use between China and oth

Heritage’s place: Heritage and narratives in city promotional films and independent documentary films in Beijing and Shanghai

This paper looks at the place of heritage in city branding in China and the different discourses and narratives found in city promotional films and independent documentary films. A city’s character is shaped by its history. All the different cultural, social and historical events that have taken place in the city inform its identity and urban form, as manifested in monuments and buildings from dif

Yields and Time-of-Flight Spectra of Neutral High-Rydberg Fragments at the K Edges of the CO2 Molecule

We have studied the production of neutral fragments in high-Rydberg (HR) states at the C 1s and O 1s edges of the CO2 molecule by performing two kinds of experiments. First, the yields of neutral HR fragments were measured indirectly by ionizing such fragments in a static electric field and by collecting resulting singly charged positive ions as a function of the photon energy. Such measurements r

Sweden: internal migration in a high-migration Nordic country

Sweden was historically, and remains, a high-migration country. The chapter considers its experience using the census and population register data that are available for the analysis of migration over long historical periods, assessing their strengths and weaknesses. It then outlines levels of inter-parish moves from 1900 to 2015 as well as moves over shorter distances from the 1970s. The former o

Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes (SUSTAIN 2) : a 56-week, double-blind, phase 3a, randomised trial

Background Semaglutide is a novel glucagon-like peptide-1 (GLP-1) analogue, suitable for once-weekly subcutaneous administration, in development for treatment of type 2 diabetes. We assessed the efficacy and safety of semaglutide versus the dipeptidyl peptidase-4 (DPP-4) inhibitor sitagliptin in patients with type 2 diabetes inadequately controlled on metformin, thiazolidinediones, or both. Method