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High-grade gliomas are one of the most aggressive human tumors with <1% of patients surviving 5 years after surgery. Immunotherapy could offer a possibility to eradicate remnant tumor cells after conventional therapy. Experimental immunotherapy can induce partial cure of established intracerebral tumors in several rodent models. One reason for the limited therapeutic effects could be immunosuppres

Landfilling is the most commonly used method for solid waste disposal in Jordan. It is an important source of pollution, which can be displayed through analysis of data for climatic conditions, hydrology and geology of the country. The migration of gas and leachate from the landfill body into the surrounding environment present a serious environmental concern, which include groundwater pollution,

The identification of serum biomarkers for the diagnosis of inflammatory bowel diseases able to reduce the need for invasive tests represents a major goal in their therapy and follow-up. We report here a methodological approach for the evaluation of specific changes in the serum peptides abundance in healthy (H) and Crohn's disease (CD) subjects, based on a label-free LC ESI/Q-TOF differential mas

A diminished capacity to maintain tissue homeostasis is a central physiological characteristic of ageing. As stem cells regulate tissue homeostasis, depletion of stem cell reserves and/or diminished stem cell function have been postulated to contribute to ageing. It has further been suggested that accumulated DNA damage could be a principal mechanism underlying age-dependent stem cell decline. We

This paper studied associations between ocular symptoms, rhinitis, throat and dermal symptoms, headache and fatigue in students by ethnicity and in relation to exposure to chemical microbial markers and fungal DNA in vacuumed dust in schools in Malaysia. A total of 462 students from 8 randomly selected secondary schools in Johor Bahru, Malaysia, participated (96% response rate). Dust was vacuumed

The intestinal mucosa represents the largest body surface toward the external environment and harbors numerous T lymphocytes that take up resident within the intestinal epithelium or in the underlying lamina propria (LP). The intraepithelial lymphocytes include subsets of 'unconventional' T cells with unclear ontogeny and reactivity that localize to this site independently of antigen-specific acti

Levels of nonantigen-induced pro-inflammatory cytokines and prostaglandin in macrophages isolated from human leucocyte antigen (HLA)-matched type 1 diabetes mellitus patients, first-degree relatives and healthy controls were determined. We hypothesize that monocytes isolated from patients are sensitized or preactivated and therefore, have an altered response to in vitro stimulus compared with cont

Pristane-induced arthritis (PIA) in rats, a model for rheumatoid arthritis (RA), is a T cell-dependent disease. However, pristane itself is a lipid and unable to form a stable complex with a MHC class II molecule. Therefore, the specificity and function of the T cells in PIA are as unclear as in rheumatoid arthritis. In this study, we show that activated CD4+ alphabetaT cells, which target periphe

BACKGROUND: Neutrophils and reactive oxygen species (ROS) are suggested to be involved in irreversible myocardial reperfusion injury and stunning. We investigated the relations between circulating biochemical markers and myocardium at risk (MaR), myocardial infarct (MI) size, salvage, and recovery of function in man. METHODS AND RESULTS: In patients undergoing PCI serial blood samples were acquir

We present a novel method for monitoring isothermal lipid hydration using a sorption microcalorimeter. A measuring cell of the double-twin calorimeter consists of two vessels connected by a stainless steel tube. The upper vessel contains pure water, and the bottom vessel is loaded with the lipid sample. This calorimeter allows for simultaneous measurement of the partial molar enthalpy and the chem

In the Democratic Republic of Congo (DRC), conflict-related sexual violence is widespread. The United Nations has made several efforts in combating this violence, for example adopting the United Nations Security Council Resolution 1820 from 2008. An interesting question is if these resolutions, which can be seen as a manifestation of an international norm that condemns sexual violence, can affect

A study done on the Harpy Tomb at Xanthus in ancient Lycia. This study is an experimental visibility analysis, the purpose of which is to explore to what extent the geometry of the bas-relief panels would be visible. Aspects which are taken into consideration for this purpose include distance and varying positions, as well as time of day. Using modern laser scanning technology and 3D processing so

Crowdfunding is often considered as a financial source to close the early stage financial gap of new ventures. However, there is little research on its impact regarding other liabilities new ventures face. The aim of this study is to find evidence on how crowdfunding can provide new ventures with additional value apart from financial resources. For this purpose, the concept of liability of newness

Det kommunala planmonopolet tillåter våra kommuner att reglera mark- och vattenanvändningen samt hur bebyggelsen ska se ut. Detta innebär en stor frihet för kommunens sida men även ett stort ansvar att hantera bygglovsansökningar på ett ansvarsfullt sätt. Det är viktigt att kommunen på ett korrekt och legitimt sätt tar hänsyn till de lagar och regler som en bygglovsprövning innefattar. Åtgärden soMunicipalities have a planning monopoly that allows them to regulate land and water use. With this follows a responsibility to handle building permits in a responsible manner. The building measure must abide by the detailed development plan. Sometimes the building measure deviates from the plan, in such cases the Building committee of the municipality can grant a building permit with a minor devia

Examensarbetets titel: Att argumentera för att konsumera. En multimetodologisk studie kring hur konsumenter argumenterar för oetisk konsumtion. Seminariedatum: 2022-06-03 Ämne/kurs: FEKH29, Examensarbete kandidatnivå i marknadsföring, 15 högskolepoäng Författare: Danira Numanspahic, Vera Pamp, Vilma Persson Handledare: Annette Cerne Nyckelord: Oetisk konsumtion, Fast fashion, The Attitude-Beh

Title:Does the announcement of cross-border acquisitions create value for the acquiring company? Seminar date: 2023-06-01 Course:FEKH89 Business Administration: Bachelor Degree Project in Financial Management Undergraduate Level, 15 ECTS credits Authors: Almegård Amélie, Andersson Sofia, Sharba Rim Advisor: Andersson, Göran Key words: Cross-border Acquisitions; Synergies; Short-term Value Cr

This thesis investigates general equality concerns regarding the current ECOFIN Pillar 2 Directive proposal from 12th of March 2022. More precisely, the author will analysis, if the Directive proposal infringes Article 20 of the Charter of Fundamental Rights through (1) directly connecting a EUR 750 threshold to its scope of application and (2) excluding specific types of entities from its scope o

Syfte: Uppsatsens syfte är att undersöka om Piotroskis F-score kan uppnå en riskjusterad överavkastning på den utvecklade europeiska marknaden samt om F-score är effektiv i att separera vinnande från förlorande aktier. Metod: Studien har genomförts med kvantitativ deduktiv metod och undersöker F-score som investeringsstrategi på den europeiska marknaden med hjälp av regressionstest baserade på riPurpose: The purpose of the study is to investigate whether F-Score, can generate significant risk-adjusted excess return in European developed markets. Furthermore, the study aims to investigate whether F-Score is an effective tool to separate winning stocks from losers. Methodology: The study has been conducted with a quantitative deductive approach and investigates F-score as an investment str