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Long-term rAAV-mediated gene transfer of GDNF in the rat Parkinson's model: intrastriatal but not intranigral transduction promotes functional regeneration in the lesioned nigrostriatal system

Previous studies have used recombinant adeno-associated viral (rAAV) vectors to deliver glial cell line-derived neurotrophic factor (GDNF) in the substantia nigra to protect the nigral dopamine (DA) neurons from 6-hydroxydopamine-induced damage. However, no regeneration or functional recovery was observed in these experiments. Here, we have used an rAAV-GDNF vector to express GDNF long-term (6 mon

Röster från socialtjänsten

Syftet med denna studie är att analysera hur personal inom socialtjänsten tolkar, definierar och upplever ett behandlingsprojekt, som involverade olika myndigheter, benämnt Motverka Våld och Gäng. Dessutom uppmärksammas hur den intervjuade och observerade personalen uppfattar och kategoriserar de inom projektet anställda samordnarna. De anställda inom socialtjänsten upplever att projektet kommit The aim of this study is to analyze how the Social Services personnel interpret, define and perceive, on the one hand, the project “Motverka Våld och Gäng” meaning “Counteract Violence and Gangs”, and on the other hand the role of the Coordinators employed in this project. Heads of units and Social Secretarys were interviewed, as well as observed and recorded at meetings. The personnel of the Soc

Planning for Solar Buildings in Urban Environments

Popular Abstract in Swedish Solenergi kommer att vara en av de viktigaste miljövänliga energikällorna i framtiden, vilket innebär ökat antal solpaneler (för el och värme) som integreras i våra hus men också som fristående produktionsanläggningar. När man planerar framtida hus och stadsdelar är det viktigt att skapa de bästa förutsättningarna för solenergi eftersom hus och stadsdelar finns kvar i fEnergy use in buildings accounts for a significant proportion of the total energy use in many countries. While past and current buildings have solely been energy consumers, future buildings will, besides using less energy, also need to produce (part of ) the required energy on site with renewables. Solar energy is generally very suitable for producing this on-site renewable energy. Although solar

One Step Forward and One Step Back. State regulation of environment and sustainable development through the use of the Education Act, school curricula and syllabuses (1990-2010)

The aim of this sociology of law-orientated article is to analyse and describe legislative and regulatory processes concerning the task given to schools focusing on environment and sustainable development. We are describing the policy-making processes in this field from 1990 to 2011. The study involves key interviews and content analysis of national policy documents as well as legal sources, in or

Principles and nomenclature for the quantification of light

This chapter does not deal with any practical aspects of light measurement, only with theoretical concepts. The following concepts are explained: energy fluence, energy fluence rate, photon fluence, photon fluence rate, radiance and mol, as well as the following superfluous or obsolete terms and synonyms: actinic flux, space irradiance, scalar irradiance, spherical irradiance, vectorial irradiance

The Laws' Properties

We are good at discussing law statements of different epistemic status, and to describe logical relationships between different law statements. But contemporary discussion often suffers from a difficulty to formulate questions concerning laws of different ontological status. This paper presents a framework for distinguishing between properties and fake properties that seems to provide better tools

Performance trade-offs in designing a dual-band CMOS IEEE 802.11A/B frontend

This paper describes trade-offs involved in designing a dual-band CMOS frontend for wireless local-area network (WLAN). Three 0.18μm CMOS frontends have been investigated, a single-band frontend at the 2.4 GHz ISM band, a single-band frontend at the 5 GHz U-NII band and a dual-band frontend. The study shows that employing a dual-band frontend yields satisfactory results, although some compromises

Dimensions of Precarity. A Contradictory Case of Non-Standard Employment.

This paper discusses the concept of ‘precarious employment’ in relation to the Swedish shipbuilding industry in the 1960s and 1970s. In this setting, characterized by shortage of labour, a dual labour market structure emerged, where some workers were directly employed by the shipyards and others indirectly employed through intermediaries. The case differs from classical accounts of dual labour mar