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The CD40-CD40L interaction plays a critical role in both humoral and cellular immune responses and interfering antibodies have been suggested as an effective approach for the treatment of lymphomas and autoimmune diseases. In this study we have profiled a panel of mouse antihuman CD40 monoclonal antibodies (MoAbs), regarding their CD40 binding affinity and epitope-specificity relative to the CD40L
Spectral tuning is a diverse topic, both with regard to mechanism and with regard to biological significance. We have touched upon a related topic already when dealing with quantum dots in Chapter 5. In organisms, spectral tuning can be achieved both by chemical means (choice of pigment) and by physical means. The latter aspect is treated towards the end of the chapter in a section on structural c
During a series of HST/STIS observations of Eta Carinae and associatedejecta, we noticed a peculiar emission filament located a few arcsecondsnorth of the central source. While bright in nebular standards, it issubmerged in a sea of scattered starlight until moderately highdispersion, long-slit spectroscopy with the STIS (R 8000) brings theemission lines out. The initial spectrum, centered on 6768
How are you supposed to define "The Baroque"? What does "Baroque literature" mean? In the frame of an encyclopedic article a reflection to this complex topic is given by highlighting the interplay of arts.
In the present paper, recordings of ‘Swedish on multilingual ground’ from three different cities in Sweden are compared and discussed.
During the last ten years or so, much effort has been spent on developing software architecture by analogy with hardware architecture from where the idea seems to originate. Much of the work has been devoted to specifying standard program units, called components, and their connections. The architecture is then the specific organization of these components and connections. In this paper, I suggest
In this paper a dialectic complexity framework is presented and reflected upon. The purpose of the framework is to guide researchers and practitioners in rethinking and reframing underlying assumptions, and address how these have a possible influence and impact on researchers’ and practitioners’ processes of making sense, understanding, explaining, improving etc. aspects of different types of issu
The interest in miniaturization of modern chemical and medical sensors is steadily increasing. However, when employing methods and fabrication procedures especially developed for microelectronics, one may encounter new and unpredictable problems for applications in aqueous media. For instance, in microelectronics often a dual metal layer system is employed for making electrical contacts. In a solu
