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This study aims to assess the effectiveness of psychosocial techniques to decrease postoperative pain and improve perioperative clinical care in orthopedic surgery. A systematic review and meta-analysis was performed to evaluate the effects of psychosocial methods among adults undergoing orthopedic surgeries. The systematic review included both randomized and nonrandomized trials, but only randomi
The co-existence of trees and grasses is a defining feature of savannah ecosystems and landscapes. During recent decades, the combined effect of climate change and increased demographic pressure has led to complex vegetation changes in these ecosystems. A number of recent Earth observation (EO)-based studies reported positive changes in biological productivity in the Sahelian region in relation to
Following John Ruggie’s UN mandate (2005-2011) the notion of human rights due diligence (HRDD) has become widely used by policymakers, corporations, NGOs and professionals. The question is whether this HRDD concept, as developed in the UN Guiding Principles (GPs), adequately addresses the deeper causes of human rights infringements in business operations. This article provides a textual and contex
Introduction: Multiple myeloma (MM) is a plasma cell neoplasm with substantial morbidity and mortality. A comprehensive description of the global burden of MM is needed to help direct health policy, resource allocation, research, and patient care.Objective: To describe the burden of MM and the availability of effective therapies for 21 world regions and 195 countries and territories from 1990 to 2
BACKGROUND: We hypothesized that reduced cerebral blood flow (CBF) and/or energy metabolic disturbances exist in the tissue surrounding a surgically evacuated intracerebral hemorrhage (ICH). If present, such CBF and/or metabolic impairments may contribute to ongoing tissue injury and the modest clinical efficacy of ICH surgery.OBJECTIVE: To conduct an observational study of CBF and the energy meta
Background: Venous thromboembolism (VTE) is the third most frequent life-threatening cardiovascular disease with an annual incidence rate of 1-2 per 1000 person-years. After the diagnosis for primary VTE, about 20-30% patients develop a recurrence within 5-years. VTE recurrence can be prevented by anticoagulants, albeit at the risk of severe bleeding. Heritability of VTE is high and hereditary fac
Introduction: The risks of preterm birth are known. We investigated the perinatal and infant mortality and morbidity after iatrogenic or spontaneous onset of extremely preterm birth. Material and methods: The present study used data from the population-based EXPRESS study comprising all infants delivered before 27+0 gestational weeks in Sweden between 2004 and 2007. All fetuses alive at admission
Introduction: Cerebrospinal fluid (CSF) biomarkers have the potential to improve the diagnostic accuracy of Alzheimer's disease, yet there is a lack of harmonized preanalytical CSF handling protocols. Methods: This systematic review summarizes the current literature on the influence of preanalytical variables on CSF biomarker concentration. We evaluated the evidence for three core CSF biomarkers:
Fifty-one half-sib families with 2768 sires were selected for this study to confirm a quantitative trait locus (QTL) detected within a previous project initiated by the German Cattle Breeders Federation (ADR). The data based on a granddaughter design were divided into two parts and were analysed using linear models and paternal half sib regression methods. The results strongly support the hypothes
A search is presented for the direct pair production of the stop, the supersymmetric partner of the top quark, that decays through an R-parity-violating coupling to a final state with two leptons and two jets, at least one of which is identified as a b-jet. The data set corresponds to an integrated luminosity of 36.1 fb-1 of proton-proton collisions at a center-of-mass energy of √s= 13 TeV, collec
RESEARCH DESIGN AND METHODS: We studied participants in PROVALID (PROspective cohort study in patients with type 2 diabetes mellitus for VALIDation of biomarkers), a prospective multinational cohort study of patients with type 2 diabetes and a follow-up of more than 24 months (n = 2,560; baseline median eGFR, 84 mL/min/1.73 m2; urine albumin-to-creatinine ratio, 8.1 mg/g). The 17 biomarkers were m
A widespread mafic sill and dyke unit (the Pedro Lessa suite) adjacent to the southeastern São Francisco (SF) craton (eastern South America) is dated as 940 ± 42 Ma, 912 ± 17 Ma, and 986 ± 64 Ma (based on combined ID-TIMS and LA-ICPMS analyses on baddeleyite grains) on the Santa Maria de Itabira gabbroic intrusion. These ages suggest membership in the previously defined ca. 920–900 Ma Large Igneou
Previous in vitro and case–control studies have found an association between the insulin-like growth factor (IGF)-axis and bladder cancer risk. Circulating concentrations of IGF-I have also been found to be associated with an increased risk of several cancer types; however, the relationship between pre-diagnostic circulating IGF-I concentrations and bladder cancer has never been studied prospectiv
The “iron triangle” phenomenon, or nexus between politicians, bureaucrats and business, is an important element of the Japanese postwar political economy system, known as the “1955 system” or “Japan Inc.” Although, originally created to facilitate high-speed economic growth by ensuring efficient cooperation between the government and business, over time it became associated with high-profile corru
Get married is the rite of passage that coincides with exit from the parental household, solemnizing the establishment of a new household and commitment to a sexual partner (Allan, G. et al, 2003:135), which is a ubiquitous phenomenon across human society. Almost all adult men and women seek to marry or form a permanent stable relationship with another person for the sake of bear children and rais
Definition: The Mbuluzi River runs through Swaziland and Mozambique into the Indian Ocean. Due to water shortage, population increase and growing industrial and agricultural sectors, high stress is being put on the water quality. The importance of keeping good water quality is accentuated by the fact that the River is shared between two countries and that it supports both capitals with drinking wa
The International Criminal Tribunals for the Former Yugoslavia and for Rwanda symbolise the commitment of the international community to put an end to impunity and to reintroduce justice and due process where it has long been denied. With the addition of the Special Court for Sierra Leone and the International Criminal Court international criminal justice has developed into a permanent feature of
The parol evidence rule is an integral doctrine of the common law contract jurisprudence. The rule was established in the 17th century English common law and has since spread amongst most of the common law jurisdictions. When the rule was first established it had a rather straightforward substantive character which forbid contracting parties who had reduced their agreement to a written instrument
Problem: Scania Commercial Vehicles (Scania CV) initiated the project, as a result of a vision regarding future preventive maintenance (PM) programmes. This vision and its core concepts will impose great changes to the way PM for heavy trucks are viewed upon at Scania CV. Within this vision many questions have risen, one of which is: How does one measure the performance of a preventive maintenance
