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Natural polymers are promising sustainable materials for diverse applications. Xylans, major components of hemicellulose, exhibit origin-dependent substitution patterns that determine their physicochemical properties. Targeted enzymatic modification of these substituents offers a mild and precise approach for tailoring the polymer's characteristics. Glucuronidases (EC 3.2.1.139) and xylan α-1,2-gl
Despite extensive cataloging of carcinogenic exposures by the International Agency for Research on Cancer (IARC) and pharmacogenomic variation by resources such as PharmVar and CPIC, few platforms unify exposure, metabolic activation and detoxification, DNA damage, and genetic annotation within a single interactive visualization framework. This gap limits systematic evaluation of gene-environment
The initial adhesion of bacterial cells to implant surfaces is a critical step in the development of biofilms, complex microbial communities that are highly resistant to conventional antimicrobial treatments. Once established, these biofilms and their self-produced extracellular matrix are difficult to eradicate. As a result, there is growing interest in engineering implant surfaces that can effec
Surgery is often viewed as a lifesaving intervention, yet recovery depends just as much on what follows. The concept of individualised anaesthesia and analgesia in surgery challenges the traditional one-size-fits-all model by tailoring care to each patient's physiological and psychological profile, with the potential to improve outcomes, reduce complications, and enhance the patient experience. Ma
We study the time complexity of computing the (min,+) matrix product of two n×n integer matrices in terms of n and the number of monotone subsequences the rows of the first matrix and the columns of the second matrix can be decomposed into. In particular, we show that if each row of the first matrix can be decomposed into at most m1 monotone subsequences and each column of the second matrix can b
As part of its efforts to secure a ‘net-zero society’, the UK government will take a strategic decision on the role of hydrogen in decarbonising homes within the next years. While scholars have recently advanced the social science research agenda on hydrogen technology acceptance, studies are yet to engage with the prospective dynamics of adopting ‘hydrogen homes’. In response, this study examines
Vehicle models are often bound by non-disclosure agreements with manufacturers.This thesis presents a vehicle model based on vehicle data gathered for the NationalAdvanced Driving Simulator in Ohio and therefore it is not bound by such limitationsand can be used in future research projects.The development and validation of the vehicle model requires understanding of thesubsystems studied, componen
Prurigo nodularis (PN) is a chronic, itchy, inflammatory skin condition that negatively affects quality of life. A study was undertaken to investigate the healthcare utilization, including treatment patterns and direct costs for specialist care, for PN in Sweden. Linkage cohorts were created from national Swedish patient and prescription registers, and the cost-per-patient database of PN adults in
This paper reviews the recent advancements in inverter topologies and control techniques for grid-connected photovoltaic systems. As photovoltaic penetration continues to increase, modern power systems need high performance inverters which can maintain reliability, power quality and compliance with evolving grid codes. Although these inverters are advancing over the years, there is no existing rev
Halide perovskite solar cells (PSCs) have emerged as a transformative photovoltaic technology, achieving unprecedented power conversion efficiencies. However, the development of electron-transport materials (ETMs), particularly organic ETMs, has significantly trailed behind the rapid progress in hole-transport materials (HTMs). Among the organic ETMs, naphthalene diimide (NDI)-based systems stand
The binder plays a crucial role in maintaining the integrity and enhancing the conductivity of the electrode, although it accounts for a small weight fraction in the entire electrode. However, the conventional binder used in lithium-sulfur (Li-S) batteries fails to effectively tackle the challenges posed by the shuttle effect of lithium polysulfides, as well as the issues of poor conductivity and
The morphogenetic protein DivIVA exhibits diverse functions across bacterial phyla. In Bacillota, DivIVA is primarily involved in cell division, whereas in Actinomycetota, it plays a central role in coordinating polar growth. Due to its essentiality in Actinomycetota, gaining insight into its structural functions is challenging. We studied truncated DivIVA proteins using a unique divIVA deletion m
Background and Objectives: Previous studies have suggested associations between pain perception and psychological factors such as mood, distress, fatigue, and quality of life. However, these factors and their relationship to pain sensitivity have typically been investigated in isolation and with insufficient sample sizes. To address these limitations, we examine the interplay between distinct psyc
Considering the distinct etiological pathways and molecular characteristics of different lung cancer subtypes, it is crucial to develop subtype-specific prevention strategies and therapeutic targets. This study aimed to identify protein biomarkers and potential therapeutic targets for specific subtypes of lung cancer by integrating population-based observational studies and Mendelian randomisation
The special degeneracy which occurs in the harmonic-oscillator potential when two of the frequencies have ratios of small integer numbers is exploited. Favored shell energies occur for particle numbers which vary with the third frequency. Applications to realistic nuclear potentials show that this degeneracy leads to special shell effects for axial shapes (1:1 ratio) but also for the 2:1 ratio exe
Integrated Continuous Biomanufacturing reduces manufacturing costs while maintaining product quality. A key contributor to high biopharmaceutical costs, specifically monoclonal antibodies (mAbs), is chromatography. Protein A ligands are usually preferred but still expensive in the manufacturing context, and batch chromatography under-utilizes the columns' capacity, compromising productivity to mai
Lead-free perovskites (LFPs) are an emergent class of materials with great potential as next-generation candidates for energy and optoelectronic applications, offering a sustainable and non-toxic alternative to their lead-based counterparts. Computational studies play a central role in accelerating the discovery, design, and optimization of these materials by enabling predictive insights into elec
Implementing the Internet of Things (IoT) into business models has become an influential catalyst, supporting novel revenue generation, improved operational efficiencies, and competitive dominance. Still, its implementation has been challenged by barriers to technological, organizational, and societal dimensions. The current study utilizes the Fuzzy Decision-Making Trial and Evaluation Laboratory
