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Erythropoietin (Epo) has been used in the treatment of anemia resulting from numerous etiologies, including renal disease and cancer. However, its effects are controversial and the expression pattern of the Epo receptor (Epo-R) is debated. Using in vivo lineage tracing, we document that within the hematopoietic and mesenchymal lineage, expression of Epo-R is essentially restricted to erythroid lin

This paper provides evidence that it is worthwhile to reconsider the traditional research circle method as a means of involving people in the third age in fulfilling their needs to participate in learning activities and make their voices heard. The findings are based on three cases of research circles consistently driven by the interests of the older participants and which increased their capacity

BACKGROUND: Reducing side effects of immunosuppressive regimens has become a priority in transplantation medicine because of the large number of patients and grafts that succumb to infection in the short term and cardiovascular disease in the long term. The Symphony study was a 12-month prospective, randomized, open-label, multi-centre, four parallel arm study that aimed to evaluate the safety and

This thesis examines the volatility in the equity and short-term interest-rate markets, and the spillover from the short term interest rate market to the equity market. It consists of three papers and focuses on adapting and proposing models for the estimation and forecasting of financial market volatility. Chapter 1 gives a brief introduction to the parametric and nonparametric volatility models,

Popular Abstract in Swedish Är muslimer så annorlunda jämfört med andra medborgare att de måste leva segregerade och separeras från resten av det svenska samhället? Vad är en muslim och vem skall definiera denna kategori? I den här avhandlingen presenteras huvudaktörerna i diskussionen och deras ideologiska synsätt. Den mångkulturalistiska ideologin är hegemonisk i Sverige när det gäller frågor soAre Muslims so different from other citizens in Sweden, that they have to live in segregation and be separated from the rest of society? What is a Muslim, and who is to define this category? In this thesis, the author presents the main actors in this discussion and their ideological positions. The multiculturalist ideology is hegemonic in Sweden on issues concerned with cultural diversity, and int

Popular Abstract in Swedish Graviditetsdiabetes (GDM) definieras som nedsatt glukostolerans av varierande svårighets¬grad som upptäcks under graviditet och som oftast försvinner efter förlossning. GDM innebär ökad risk för såväl moder som barn. Kvinnor med GDM föder ofta stora barn och har ökad risk för komplikationer i samband med förlossningen. GDM-prevalensen varierar avsevärt mellan olika popuGestational diabetes mellitus (GDM) is a heterogeneous disorder that is defined as carbohydrate intolerance with onset or first recognition during pregnancy. Impaired beta-cell function and insulin resistance are the hallmarks of GDM. The overall aim of this thesis was to study the genetic and immunological risk factors that increase susceptibility to GDM. First, we investigated whether autoimmuni

This thesis analyses the energy consumption of the Italian and Swedish residential sector during the last two decades. It has two main purposes: (1) to test the Environmental Kuznets Curve (EKC) hypothesis that stipulate a decoupling relation between environmental harm and economic growth and (2) to investigate on four factors that could explain such decoupling relation. The key factors are the ch

This study explores the contexts in which the conflict evolved and how history was perceived, narrated and used by institutions, communities and individuals who sought to influence public opinion and policymakers. The theoretical point of departure is the concept of collective memory, defined as the totality of discourses through which a society makes sense of itself, the present and the future th

Renewable energy is gaining increasing importance in the generation of power due to the finite existence of fossil fuels and concerns about climate change. As its demand grows financial interest from investors’ increases, thus it is important to find the most effective way of quantifying the risk of the renewable energy market. Furthermore as renewable energy can be viewed as an economic substitut

In this project the aim was to design a concrete 3d printer. This report focuses on the extruder part of the printer and the printing material. The basic principle of 3d printing is that it is an additive manufacturing technique, on the contrary to the traditional subtractive manufacturing techniques. The potential benefits of concrete 3d printing compared to the techniques that are used today are

The aim of this thesis is to examine how Turkey’s “proto-transition” regarding the Kurdish issue is gendered in the light of the narratives of a particular set of victims, the wives of the disappeared. The conflict between the Turkish military and the Kurdistan Workers’ Party (Partiya Karkerên Kurdistan or PKK) has been ongoing for more than three decades. During 1980s and 1990s, enforced disappea

How we choose to invest in the future generations is becoming increasingly imperative as researchers learn more about the long-term consequences of early childhood. The early-life literature suggests that empowered mothers invest more into their children and that matrilineal females are more empowered than patrilineal counterparts. To further understand the role of female empowerment on early chil

Early-life health shocks can have very serious long-term consequences for those exposed to them, a fact which must be considered when parents make decisions with regards to allocating resources across their children. Here, the 1980 famine in Karamoja, Uganda is used as a natural experiment in which to test whether parental investment responses reinforce or compensate the impacts of early-life shoc

The Fidesz government has likely had an impact on the Hungarian economy through the “nationalistic” policies implemented. The analysis in this thesis aims to calculate the extent of the economic impact of the Fidesz government on the Hungarian economy in the period 2010 till 2018. Moreover, in Hungary the regional economic inequality is significant. The second aim of the analysis is to see how the

on the 21st of September, the CJEU delivered the judgements in DNB Banka and AVIVA, clearly stating that the cost sharing exemption cannot be relied upon by taxable persons operating in the financial and insurance sectors, due to the fact that the scope of Article 132(1)(f) is limited to exemptions in the public interest. This paper will look at the purpose and the development of Article 132(1)(f)