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Glucocorticoids improve erythroid progenitor maintenance and dampen Trp53 response in a mouse model of Diamond-Blackfan anaemia.

Diamond-Blackfan anaemia (DBA) is a rare congenital disease causing severe anaemia and progressive bone marrow failure. The majority of patients carry mutations in ribosomal proteins, which leads to depletion of erythroid progenitors in the bone marrow. As many as 40% of all DBA patients receive glucocorticoids to alleviate their anaemia. However, despite their use in DBA treatment for more than h

What Happened to 'Race' in Race Biology? The Swedish State Institute for Race Biology, 1936-1960

The Swedish State Institute for Race Biology (SIRB) was founded in 1921 and immediately became the most important institution for racial science in Sweden. We know a great deal about the history of SIRB until 1935, when right-wing director Herman Lundborg retired and was replaced by the left-wing, anti-fascist Gunnar Dahlberg. In this essay, the later history of SIRB is for the first time examined

Enhancing mitochondrial function in vivo rescues MDS-like anemia induced by pRb deficiency

Erythropoiesis is intimately coupled to cell division, and deletion of the cell cycle regulator retinoblastoma protein (pRb) causes anemia in mice. Erythroid-specific deletion of pRb has been found to result in inefficient erythropoiesis because of deregulated coordination of cell cycle exit and mitochondrial biogenesis. However, the pathophysiology remains to be fully described, and further chara

Convergence Speed of Coupling Iterations for the Unsteady Transmission Problem

We present an estimate for the convergence rate of the Dirichlet-Neumann iteration for the discretized unsteady transmission problem. Specifically, we consider the coupling of two heat equations on two identical squared domains. The Laplacian is discretized by second order central finite differences and the implicit Euler method is used for the time discretization. For the semidiscrete case, Hensh

A lipid-based passivation scheme for nanofluidics

Stretching DNA in nanochannels allows for direct, visual studies of genomic DNA at the single molecule level. In order to facilitate the study of the interaction of linear DNA with proteins in nanochannels, we have implemented a highly effective passivation scheme based on lipid bilayers. We show long-term passivation of nanochannel surfaces to several relevant reagents and demonstrate that the pe

Separation of deformable hydrogel microparticles in deterministic lateral displacement devices

To better understand how deformable and non-spherical particles behave in sorting devices based on deterministic lateral displacement we generate models of biological particles with tunable size, shape and mechanical properties using stop-flow lithography and we explore how these parameters play a role in our separation devices. Hollow and solid cylinders are compared with respect to their deforma

A high-throughput deterministic lateral displacement device for rapid and sensitive field-diagnosis of sleeping sickness

We present a simple and rapid microfluidic device capable of extracting and concentrating the parasite causing the fatal disease sleeping sickness (SS) from blood. The device is based on deterministic lateral displacement (DLD) and constructed with a single inlet with flow induced by an ordinary syringe. The simplicity is crucial as the device is intended for use in the resource depraved areas whe

The stereotype of women in Yemeni Folk Literature

Although folk culture in Yemen is characterised by respect for women and their role in society, folktales contain stereotypical patterns that are not very different from the negative portrayals of women in other media. Folktales in Yemen create a negative image of women, but this image is hidden under the aesthetic aspect, as cultural patterns embedded in the consolidation of this negative image.

Dynamic changes of excitatory amino acid receptors in the rat hippocampus following transient cerebral ischemia

The changes in excitatory amino acid receptor ligand binding induced by transient cerebral ischemia were studied in the rat hippocampal subfields. Ten minutes of ischemia was induced by common carotid artery occlusion combined with hypotension, and the animals were allowed variable periods of recovery ranging from 1 day to 4 weeks. The binding of 3H-AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole

A candidate CpG SNP approach identifies a breast cancer associated ESR1-SNP.

Altered DNA methylation is often seen in malignant cells, potentially contributing to carcinogenesis by suppressing gene expression. We hypothesized that heritable methylation potential might be a risk factor for breast cancer and evaluated possible association with breast cancer for single nucleotide polymorphisms (SNPs) either involving CpG sequences in extended 5'- regulatory regions of candida

2014cv helenenymann

2012-2014 2007-2010 2006-2007 2005 2011 2010 2016 2015 2014 2013 2012 2011 2010 Malmø Art Academy, Post graduate Diploma MFA Fine Art, Sweden Goldsmiths, University of London, Honours BA Fine Art Practice, United Kingdom Central Saint Martins, University of London, Performance design, United Kingdom Bjørn Ignatius Øchenholts Billedkunstskole, Copenhagen, Denmark Film Editor at DFI / The Danish Fil

https://www.khm.lu.se/sites/khm.lu.se/files/2014cv_helenenymann.pdf - 2026-06-08

Sasi03 study guide update 140218

SASI03: Environmental Studies and Sustainability Science: Concepts, Challenges and Approaches in Sustainability Studies Study guide 7.5 credits Spring 2018: 15th January- 19th March Schedule Day Date Time Venue Title Teacher Week 1 Mon 15/1 10-12 Wrangel Library Roll-call & course introduction Mandatory Stephen Woroniecki Wed 17/1 13-15 Carson Key concepts, debates and history of Environmental and

https://www.lumes.lu.se/sites/lumes.lu.se/files/sasi03_study_guide_update_140218.pdf - 2026-06-08

Marie vaillant

Environmental Non-Governmental Organisations' (ENGOs) participation in the process of sustainable spatial planning implementat ENGOs as a tool to implement sustainable spatial Planning? LUMES THESIS 2004-2005 Vaillant Marie Environmental Non-Governmental Organisations' (ENGOs) participation in the process of sustainable spatial planning implementation By Marie VAILLANT Submitted in partial fulfill

https://www.lumes.lu.se/sites/lumes.lu.se/files/marie_vaillant.pdf - 2026-06-08

Samson abaya

Microsoft Word - MSc_FINAL_THESIS_SAMSON_WAKUMA Floods and Health in Gambella region, Ethiopia: An Assessment of the strength and weakness of the coping mechanism M.Sc. Thesis submitted to Lund University Centre for Sustainability Studies By: Supervisor: SAMSON WAKUMA ABAYA GÖRAN EWALD (PhD) MAGISTRATSVAGEN55K:108 LUCSUS, LUND UNIVERSITY SE-22644, LUND SOLVEGATAN 10, SE-22100 SWEDEN LUND, SWEDEN S

https://www.lumes.lu.se/sites/lumes.lu.se/files/samson_abaya.pdf - 2026-06-08