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Changes in the Arctic's climate are a result of complex interactions between the cryosphere, atmosphere, ocean, and biosphere. More feedbacks from the cryosphere to climate warming are positive and result in further warming than are negative, resulting in a reduced rate of warming or cooling. Feedbacks operate at different spatial scales; many, such as those operating through albedo and evapotrans

Nontypeable Haemophilus influenzae (NTHi) is one of the main aetiologies of childhood bacterial infections as well as exacerbations in COPD patients. Currently, no licensed NTHi vaccine exists. In the present study, we evaluated the potential of the conserved and ubiquitous surface protein Haemophilus Protein F (PF) as a vaccine candidate. Our results show that incubation of NTHi with anti-PF anti

Human neutrophils are activated by the beta-galactoside-binding lectin galectin-3, provided that the cells are primed by in vivo extravasation or by in vitro preactivation with, for example, LPS. Removal of terminal sialic acid can change neutrophil functionality and responsiveness due to exposure of underlying glycoconjugate receptors or change in surface charge. Here, we investigated whether suc

The paper deals with the ways an advanced digital technology like GPS (Global Positioning System) is integrated with the mundane practices of wayfinding and moving on foot. I will use N Katherine Hayles take on the concept cognisphere: ”The cognisphere gives a name and shape to the globally interconnected cognitive systems in which humans are increasingly embedded.” The concept deals with the ways

CREB3L2 was first identified as the 3'-partner of FUS in a fusion gene that seems to be specific for low grade fibromyxoid sarcoma. In silico analyses suggest that the predicted CREB3L2 protein is a member of the CREB3 family of transcription factors, with its bZIP domain being highly similar to that in CREB3L1, CREB3L3, CREB3L4, CREB3, and Drosophila Bbf-2. In the present study, the authors asses

We have earlier shown that galectin-3, a lactose-binding mammalian lectin that is secreted from activated macrophages, basophils, and mast cells, induces activation of the NADPH oxidase in exudated but not in peripheral blood neutrophils (A. Karlsson, P. Follin, H. Leffler, and C. Dahlgren, Blood 91:3430-3438, 1998). The alteration in responsiveness occurring during extravasation correlated with m

Self-incompatibility (SI) in the Brassicaceae plant family is controlled by the SRK and SCR genes situated at the S locus. A large number of S haplotypes have been identified, mainly in cultivated species of the Brassica and Raphanus genera, but recently also in wild Arabidopsis species. Here, we used DNA sequences from the SRK and SCR genes of the wild Brassica species B. cretica, together with p

Emerging knowledge of cartilage metabolism and structure has stimulated efforts to develop new cartilage-monitoring techniques in health and disease. This article gives an overview of cartilage matrix structure, cartilage metabolism, and significant exogenous factor's to show how such knowledge can guide the development of new means to monitor cartilage. Delayed contrast enhanced MRI of cartilage

OBJECTIVE--The aim was to investigate associations between exposure to mineral fibres and dust, and cancer in subsites within the large bowel. DESIGN--Pooled retrospective cohort studies. SUBJECTS AND SETTINGS--Blue collar workers, employed for at least one year in different trades; asbestos cement or cement workers (n = 2507), other industrial workers (n = 3965), and fishermen (n = 8092). MAIN OU

Popular Abstract in Swedish Den huvudsakliga hämmande signalsubstansen i hjärnan är GABA (gamma-aminobutyric acid, gamma-aminosmörsyra). GABA finns i ungefär hälften av alla nervceller i hjärnan och alla nervceller i hjärnan antas ha receptorer som binder GABA. Om man tänker på alla de normala neurologiska funktioner samt rubbningar där GABA är involverat är det inte svårt att förstå GABA:s oerhörInhibitory neurotransmission in the brain is mostly mediated by gamma-aminobutyric acid type A (GABAA) receptors. These receptors are involved in both phasic inhibition (point-to-point inhibition, synaptic transmission) and tonic inhibition (diffuse form of inhibition, brain homeostasis). In this thesis the functional and pharmacological properties of GABAA receptors expressed in brain slices or i

OBJECTIVES: The methyltransferase genotype and pregnancy both influence the arsenic metabolism phenotype, but it is unknown whether these factors interact, explaining the drastic changes in the efficiency of arsenic metabolism observed among pregnant women. The aim of this study was to evaluate the relative contribution of the methyltransferase genotype and pregnancy to the arsenic metabolism phe

A measurement of the Lambda(0)(b) lifetime and mass in the decay channel Lambda(0)(b) -> J/psi (mu(+) mu(-))Lambda(0)(p pi(-)) is presented. The analysis uses a signal sample of about 2200 Lambda(0)(b) and (Lambda) over bar (0)(b) decays that are reconstructed in 4.9 fb(-1) of ATLAS pp collision data collected in 2011 at the LHC center-of-mass energy of 7 TeV. A simultaneous mass and decay time ma

In 1919 the now largely forgotten popular novelist E.M. Hull sparked a decade of infatuation with the ‘desert romance’ on the publication of her first book, The sheik. The obsession with the genre, fuelled by the release of Melford's 1921 film adaptation of the book, saw women swooning in the aisles at ‘screen god’ Rudolph Valentino's starring role. My aim here is to broaden the focus on Hull away

Knowledge of a patient's perception of her medical needs and urgency may make it possible for emergency nurses to communicate the triage decision and make the patient understand the assessment and triage category. The aim of this study was to compare the patients' own assessments of their acuity to the triage nurse's assessment, as well as describe patient satisfaction and levels of anxiety.

This thesis has two aims: to expand the range of the field of human geography research; and to establish the importance of the geographical perspective for understanding the role of sustainability in human behaviour.

The Parkinson’s Disease Questionnaire – 39 is the most widely used disease-specific health status questionnaire for Parkinson’s disease. Evaluations of various language versions have focused on psychometric properties, whereas documented evaluations regarding linguistic validity, respondent burden and questionnaire content are largely lacking. Work with the Swedish Parkinson’s Disease Questionnair