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Introduction: The PRODIGE 7-trial investigated the additional value of Hyperthermic Intraperitoneal Chemotherapy (HIPEC) to cytoreductive surgery (CRS) for patients with colorectal peritoneal metastases (CPM). The results of PRODIGE 7 were presented at the 2018 ASCO meeting showing that 30 min oxaliplatin-based HIPEC did not improve overall survival. The current study investigated the impact of PR
Background: The LUCAS™ device delivers mechanical chest compressions that have been shown in experimental studies to improve perfusion pressures to the brain and heart as well as augmenting cerebral blood flow and end tidal CO2, compared with results from standard manual cardiopulmonary resuscitation (CPR). Two randomised pilot studies in out-of-hospital cardiac arrest patients have not shown impr
Aim: To describe fathers’ lived experiences of caring for their preterm infant at the neonatal unit and in hospital-based neonatal home care after the introduction of an individualised parental support programme. Method: Seven fathers from a larger study were included due to their rich narrative interviews about the phenomenon under study. The interviews took place after discharge from neonatal ho
Natural hybridization occurs commonly in plants and blurs their interspecific delimitation. It is unclear whether spontaneous hybridization occurs in natural populations of Primula in China. In this study we examined natural hybridization between P. secundiflora and P. poissonii based on morphological and molecular analyses of individuals with intermediate morphology. Most morphological characters
Introduction The provision of healthcare for patients with inflammatory arthritis occurs in the context of somewhat conflicting targets, values and drivers. Therefore, there is a need for introducing 'value-based healthcare' defined as the value of patient relevant health outcomes in relation to costs. This term is a central part of tomorrow's healthcare sector, especially for rheumatic diseases,
The purpose of this study was to evaluate the effect of different choices of adaptation strengths on image quality and radiation exposure to the patient with Siemens automatic exposure control system called CARE Dose 4D. An anthropomorphic chest phantom was used to simulate the patient and computed tomography scans were performed with a Siemens SOMATOM Sensation 16 and 64. Owing to adaptation stre
This study deals with physical education (PE) in secondary school. The purpose of the study is to analyze the relationship between PE in secondary schools and leisure time sports. Questions were directed towards discovering what PE teachers recognise as valuable in their teaching, and how physical education is related to factors that characterize the field of sports. The teaching practice of Physi
The single Trp of human cystatin C, Trp-106, is located in the second hairpin loop of the proteinase binding surface. Substitution of this residue by Gly markedly altered the spectroscopic changes accompanying papain binding and reduced the affinity for papain, actinidin, and cathepsins B and H by 300-900-fold. The decrease in affinity indicated that the side chain of Trp-106 contributes a similar
Med start år 1967 har folkrätten fått en rad tillskott av multilaterala överenskommelser genom uppkomsten av en ny typ av traktat. Dessa traktat har skapats för att stifta så kallade kärnvapenfria zoner och är i grunden folkrättsligt bindande överenskommelser som etablerar komplett nedrustning av kärnvapen inom ett geografiskt avgränsat område. Det internationella samfundet har under flera decenniSince 1967, public international law has had many treaty additions through so-called nuclear weapon free zones, treaties that have been created through legally binding agreements to pursue complete nuclear disarmament within a geographically defined area. The international community has for decades discussed the establishment of such a zone in the Middle East, but without prompting any concrete ac
The Anthropocene is facing complex issues that require paradigmatic shifts in thought and action. In this context, systemic change and cross-sectoral partnerships have gained an exceptional wave of support through agreements such as Agenda 2030, shaping the landscape of international development cooperation sector. However, conceptual limitations and methodological gaps pose challenges to understa
Abstract in Danish Denne afhandling handler om livskvalitet hos ældre mennesker med kræft. Risikoen for at få kræft stiger med alderen, og til trods for at de fleste mennesker, der får kræft er ældre, har forskning i hvordan ældre lever med en kræftsygdom været yderst begrænset. Viden om hvordan ældre mennesker oplever det at få en kræftdiagnose og hvordan de lever med sygdommen er en forudsætningOver the coming decades, the numbers of elderly will increase, and through improved lifestyles and better treatment longevity has increased, and with it, the risk of contracting cancer. How elderly people live with cancer has until now attracted limited research. The overall aim of this thesis was to investigate the QoL of elderly persons from the time of a cancer diagnosis through the following s
This thesis presents the design and implementation of a Geographic Information System (GIS) for the Naoussa Municipality Water and Sewer Company for better water utility management. The methodology contained field data collection like the valves, sewer manholes, hydrometers, and hydrants in two ways, UAV photogrammetry, and traditional surveying, the georeferencing process, photogrammetric proces
Unsafe abortion is a major contributing factor to maternal mortality with 47,000 largely avoidable deaths occurring globally every year, the majority in the global south. Ethiopia has taken a unique approach to addressing maternal mortality impacted by unsafe abortion through a 2005 reform of the abortion legislation in which abortion is illegal but available under a range of exceptions. The purpo
The European Union is often portrayed as a soft, civilian power. In this thesis we question this view of the Union, by comparing it to the United States of America; usually described as a hard power user. We compare the foreign policy actions of the EU and the US in the seventeen conflicts of 2004. With help from K. J. Holsti's division of strategies to exercise power we create our own tool fo
The concept of social sustainability is difficult to define and is often perceived as broad. The aim of this thesis is to narrow it down, in a perspective concerning the Right to the City. The thesis also aims to examine how planning for the Right to the City in conjunction with social sustainability, through planning for social mix, might lead to a process of gentrification. The object of the stu
Based on the debate in the media following the SOU (2003:49)-reports different suggestions to strengthen the childs role in the adoption process, we started considering the adoptive parents reactions to all this. Has anyone asked them? What support would they want? The objective of our paper was to present the result of a number of interviews with adoptive parents regarding some of the questions f
Den senaste tidens framväxt av miljötvister på internationell nivå har väckt frågan vilka instrument som finns tillgängliga för miljöskydd. Särskilt relevant har frågan varit hur miljöskydd och grundläggande rättigheter kan kombineras. Denna uppsats syftar till att undersöka på vilka sätt miljöskydd och grundläggande rättigheter har strålat samman på europeisk nivå, genom att studera miljöskyThe recent surge in environmental litigation on an international level has posed the question what instruments there are available for environmental protection, especially combining environmental protection with fundamental rights. This thesis seeks to examine in what ways environmental protection and fundamental rights have converged on an European level, through studying the environmental p
Podcastformatet som arena för politiserad maskulinitet, författad av Jens Kraemer, Alexander Holm & Jeppe Truedsson, är skriven inom ämnet Medie- och kommunikationsvetenskap vid Institutionen för kommunikation, Lunds universitet. Studien undersöker hur idéer om maskulinitet och antifeminism, med grund i den digitala manosfären, kommer till uttryck och ges politisk betydelse i samtida digital m
Most of the ecotoxicological research conducted in the Arctic until today has focused on long range transport of pollutants, while fewer studies on local pollution have been published. The aim of this study was hence to investigate if local pollution of organophosphorus flame retardants (OPFRs), polybrominated diphenyl ethers (PBDEs) and perfluorinated alkylated substances (PFAS) occurs outside tw
