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Indirect Striatal Projection Neurons Drive a D2 Receptor-Dependent Pathway to Dyskinesia and Dystonia

Background: L-DOPA-induced dyskinesia is attributed to opposite activity changes mediated by D1 and D2 dopamine receptors in the two striatal output pathways. Whereas the causal role of direct-pathway D1 receptors is well established, the specific involvement of indirect-pathway D2 receptors in dopaminergic dyskinesias has remained elusive. Objectives: We used conditional knockout approaches in mi

Synovial monocytes contribute to chronic inflammation in childhood-onset arthritis via IL-6/STAT signalling and cell-cell interactions

INTRODUCTION: Monocytes are key effector cells in inflammatory processes. We and others have previously shown that synovial monocytes in childhood-onset arthritis are activated. However, very little is known about how they contribute to disease and attain their pathological features. Therefore, we set out to investigate the functional alterations of synovial monocytes in childhood-onset arthritis,

Mves01 2020 preliminart schema

SCHEDULE EMSBVC+MIN (MESPOM+ENV SCI) 2020 MVES01 Miljöstyrning i näringslivet HT 2020 - PRELIMINÄRT SCHEMA Rött = både miljövetare och MESPOM-studenter Orange = bara miljövetare Mörka färger är klassrumsaktiviteter Ljusa färger är egen studietid/grupparbete 36 Monday 31 August Tuesday 1 September Wednesday 2 SeptemberThursday 3 September Friday 4 September 08.15 - 09.55 Course MESPOM+ENV SCI/onsit

https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/mves01_2020_preliminart_schema.pdf - 2026-06-08

Vt13-kp-smla04-2013-02-06

• • • 1. Fastställande Kursplanen är fastställd av Samhällsvetenskapliga fakultetens styrelse 2009-05-19 och senast reviderad 2013- 02-06 av Ledningsgruppen för kandidatprogrammet i Food Service Management och Logistics Service Management. Den reviderade kursplanen gäller från och med 2013-02-25. Utbildningsområde: Samhällsvetenskapligt 100% Ansvarig institution: Inst för Service Management 2. All

https://www.ses.lu.se/sites/ses.lu.se/files/vt13-kp-smla04-2013-02-06.pdf - 2026-06-08

Understand Explain Improve 2020 Copy

Understand, explain, improve – thematic collaborations 2020, Lund University Understand, explain, improve THEMATIC COLLABORATIONS | LUND UNIVERSITY EDITOR AND LAYOUT Bodil Malmström, Cooperation office Research, Collaboration and Innovation, Lund University TEXT Catrin Jakobsson, Noomi Egan, Jessika Sellergren, Bodil Malmström och Pia Romare. PHOTO Johan Bävman, Salar Haghighatafshar, Catrin Jakob

https://www.staff.lu.se/sites/staff.lu.se/files/2021-09/Understand%20explain%20improve%202020%20copy.pdf - 2026-06-08

Intention in Hybrid Organizations: The Diffusion of the Business Metaphor in Swedish Laws

Recent studies of conceptual metaphors in a legal context have often dealt with the power of embodiment. However, the connotations of culturally originated metaphors could be different when they appear in laws and regulations. In particular, the role of metaphor when the legislator wishes to define intention in hybrid organizations is investigated here. The case studied is how a conceptual metapho

Questions of Method in James Dunn's Jesus Remembered

Parts of Dunn's methodology in "Jesus Remembered" (2003) are scrutinised: the meaning of "memory" and whether this is the ultimately attainable object of historiography. I contend that historical research should not content itself with investigating how memories are "fictionalized", i.e. retained in narrative form, but press on to verified judgments on historical facts. "Grand (or: master) narrati

Analysis of strongly interfering slow frequency-hopping systems

In this report slow frequency-hopping systems are analyzed with respect to the probability of successful transmission of packets, and with respect to the throughput. It is assumed that collisions result in a loss of all information contained in the colliding packets, irrespective of the distance between the units of the system. Units transmit packets of different types with a certain probability,

Study of Particle Size Dependant Reactivity in an α-TCP Orthophosphate Cement

Calcium phosphates have been of great interest in the field of medicine for many decades due to their biocompatibility, hardening properties and diverse areas of application. In this study two different alpha phase tricalcium phosphate powders were produced of distinctly different particle size distributions. These two powders were then tested for reactivity and phase evolution. X-ray diffraction

A study of the performance of risk and vulnerability assessments by Swedish Public Agencies

Risk and vulnerability assessments (RVA) are vital components of the work conducted by public agencies at different levels, as part of the processes for governing and managing risks in the society. In Sweden, public agencies at all levels are required by legislation to perform risk and vulnerability assessments within their respective area of responsibility. The present paper presents a study of h

Viscosity Model Uncertainties in an Ash Stabilization Batch Mixing Process

Recycling wood ash from burnt wood (back to the forest grounds) is of great ecological importance. However, the ash cannot be recycled directly after combustion. There are several reasons for this, one being the volatility of wood ashes. Mixing ash/dolomite/water in order to obtain granular material is one method to stabilize wood ashes. The main problem is predicting the quantity of water to be a

Are We All Spiritual?

'I’m spiritual – not religious' has become a key expression of a new form of globalized religion focussing on a specific notion of spirituality, signifying a universal human essence, located deep inside each individual as a potential for wellbeing and personal transformation. The message is: Spirituality unites us into a single humanity, while religion, with its dogma and rituals, separates us. Th

Quantification of left-to-right shunt through patent ductus arteriosus by colour Doppler in children admitted for a device closure

Purpose: Our animal model suggests that quantification of ductal flow from colour Doppler pixels is possible. We aimed to clarify whether this method can be used to determine a clinically significant ductal shunt in children. Methods: We retrospectively quantified ductal flow from saved images from 20 children who had been admitted for device occlusion of patent ductus arteriosus. Colour Doppler i

Design with architectural objects in industrialised house-building

This paper introduces a research project with the aim to develop concepts and tools for architectural design, taking the ideas of "behaviour settings" as a starting point, to enable a more relevant holistic view in object oriented design of buildings. In this paper we introduce the concept of "architectural object" as a representation of a real "situation" involving people, behaviour, experience a