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Intermittent PTH((1-34)) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures.

Intermittent Parathyroid Hormone (PTH)((1-34)) has an established place in osteoporosis treatment, but also shows promising results in models of bone repair. Previous studies have been dominated by closed fracture models, where union is certain. One of the major clinical needs for anabolic therapies is the treatment of open and high energy fractures at risk of non-union. In the present study we th

Late Quaternary glaciation history of Isla de los Estados, southeasternmost South America

Isla de los Estados is a mountainous island southeast of Tierra del Fuego, in southernmost South America. Its central and eastern parts have an alpine topography, transected by U-shaped valleys, small, partly over-deepened fjords, and a multitude of abandoned cirques, all associated with extensive former local glaciations. Traces of glacial erosion generally reach 400-450 m a.s.l., and above that

Signals of tree volume and temperature in a high-resolution record of pollen accumulation rates in northern Finland

Pollen accumulation rates (PARs) provide a potential proxy for quantitative tree volume (m3 ha-1) reconstruction with reliable absolute pollen productivity estimates (APPEs). We obtained APPEs for pine, spruce and birch at their range limits in northern Finland under two temperature periods (warm and cold) based on long-term pollen trap and tree volume records within a 14-km radius of each trap. A

Process based Modelling of Chemical and Physical Aerosol Properties Relevant for Climate and Health

Atmospheric aerosol particles have substantial influence on climate and air quality. However, the anthropogenic influence on the atmospheric aerosol is still poorly known. This limits the understanding of past and future climate changes. Additionally, both epidemiological and toxicological studies indicate adverse health effects of inhaled aerosol particles. In order to study the effect of atmosph

New Families of LDPC Block Codes Formed by Terminating Irregular Protograph-Based LDPC Convolutional Codes

In this paper, we present a method of constructing new families of LDPC block code ensembles formed by terminating irregular protograph-based LDPC convolutional codes. Using the accumulate-repeat-by-4-jagged-accumulate (AR4JA) protograph as an example, a density evolution analysis for the binary erasure channel shows that this flexible design technique gives rise to a large selection of LDPC block

Decision support for product release planning based on robustness analysis

Decision-making in requirements engineering often needs to be done in the presence of uncertainty. Rigorous methods can help to increase the probability of making the most appropriate decisions under the given circumstances. Robustness is a measure for the degree of stability of a solution in case of changes in the problem parameters. This paper presents a method (called DECIDERelease) that applie

Severe Hemodilution - Clinical and Experimental Studies

Popular Abstract in Swedish Under det senaste decenniet har risker med och alternativ till allogent blod (blod från främmande givare) debatterats mycket pga. risken för smitta, allergiska reaktioner, samt starka indicier som talar för att blod från främmande givare kan påverka immunförsvaret hos mottagaren. Därför vill man gärna begränsa mängden tillfört givarblod under kirurgiska ingrepp på barn,In children, it is often desirable to minimize allogenic blood transfusion, and this thesis explores the physiology of an alternative method of managing perioperative blood loss: hemodilution with Ringer´s dextran. Methods Clinical studies: Arterial pressure, superior caval venous oxygen saturation (ScvO2) and blood lactate concentration (L) were studied during bone marrow harvesting (BMH) on 23

Mutation Analysis and Hypercholesterolemia: Studies in FH patients and in healthy middle-aged men with high, low, or increasing cholesterol levels during a six-year follow-up (the CRISS study).

Our aims were to characterize familial hypercholesterolemia (FH) in a Swedish FH population and to further elucidate the clinical expression and treatment response in relation to genotype. Secondly, we wanted to identify gene variants, which may have impact on cholesterol levels in apparently healthy subjects. In the search for sequence alterations in the large LDL receptor gene we introduced and

From Product Codes to Structured Generalized LDPC Codes

Product codes, due to their relatively large minimum distance, are often seen as a natural solution for applications requiring low error floors. In this paper, we show by means of an ensemble weight enumerator analysis that the minimum distance multiplicities of product codes are much higher than those obtainable by other generalized LDPC (GLDPC) constructions employing the same component codes. W

Forest-edge effects on sea-salt aerosol deposition: a wind-tunnel study using living oak leaves

Landscape patchiness creates aerodynamic transition zones that affect the exchange of nutrients and pollutants between the atmosphere and vegetation. Using an artificially-generated NaCl aerosol (mass-versus-particle-size distribution with aerodynamic mean particle diameter 1.6 mu m; geometric standard deviation 1.9), we investigated the forest-edge effect on aerosol deposition within a model oak

Early clinical outcome of aortic transcatheter valve-in-valve implantation in the Nordic countries

Objective: Transcatheter valve-in-valve implantation has emerged as an option, in addition to reoperative surgical aortic valve replacement, to treat failed biologic heart valve substitutes. However, the clinical experience with this approach is still limited. We report the comprehensive experience of transcatheter valve-in-valve implantation in the Nordic countries from May 2008 to January 2012.

A diatom record of mid- to late Holocene palaeoenvironmental changes in the southern Okinawa Trough

Palaeoceanographic changes over the last 6800 years are documented in a diatom record from core MD05-2908 from the southern Okinawa Trough. Changes in diatom components are used to reflect variations in the strength of the Kuroshio Current and the influence of coastal waters, and these changes are compared with records of the East Asian summer monsoon, which exerts an important influence on region

Does SISCOM contribute to favorable seizure outcome after epilepsy surgery?

Purpose: To assess the additional value of subtraction ictal single-photon emission computed tomography (SPECT) coregistered to MRI (SISCOM) for localization of the epileptogenic zone in patients with drug-resistant epilepsy scheduled for invasive video-EEG (VEEG) before epilepsy surgery by a descriptive study from clinical practice. Methods: Forty-nine consecutive epilepsy patients between Januar

Sealed Glass Tube Combustion of mu g-Sized Aerosol Samples

It is important to evaluate each step in radiocarbon analysis to ensure that the whole process is as efficient and accurate as possible. Aerosol filter samples contain a myriad of carbonaceous compounds with varying resistance to oxidation. Complete combustion of the sample is thus of great importance to ensure that the graphitized sample is representative of the original filter sample. We have ev

Connecting Spatially Coupled LDPC Code Chains

Codes constructed from connected spatially coupled low-density parity-check code (SC-LDPCC) chains are proposed and analyzed. It is demonstrated that connecting coupled chains results in improved iterative decoding performance. The constructed protograph ensembles have better iterative decoding thresholds compared to an individual SC-LDPCC chain and require less computational complexity per bit wh