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Alzheimer’s disease affects millions of lives worldwide. This terminal disease is characterized by the formation of amyloid aggregates, so-called amyloid oligomers. These oligomers are composed of β-sheet structures, which are believed to be neurotoxic. However, the actual secondary structure that contributes most to neurotoxicity remains unknown. This lack of knowledge is due to the challenging n
The study analyses postfeminism in an organisational context from a critical feminist perspective by exploring the contemporary perceptions of gender and gender equality in a female student career network. Furthermore, the study aims to investigate how these perceptions are projected and how they relate to organisational values, principles and processes of the organisation. Hence, How does postfem
Hjärntumörer utgör omkring 2 procent av alla cancerdiagnoser och den vanligaste elakartade hjärntumörtypen är glioblastom (GBM). Patienter med GBM behandlas i dag med kirurgi, cellgifter och strålbehandling, men sjukdomen går sällan att bota och det krävs nya och mer effektiva behandlingsstrategier.I min doktorsavhandling har jag använt tre olika musmodeller, kallade GL261, KR158 och SB28, för attAdvances in surgery, chemo- and radiotherapy have only modestly improved survival rates of malignant brain tumor patients during the last decades. Emerging evidence suggests that an efficient treatment of malignant brain tumors will likely require the management of multiple aspects of tumor pathobiology in order to manipulate features as tumor heterogeneity and tumor immunosuppression. Immunothera
Background: Despite its well-established positive effects, exercise-based cardiac rehabilitation (exCR) is underused in patients following an acute myocardial infarction (AMI). The aim of the study was to identify factors associated with non-Attendance at exCR in patients post-AMI in a large Swedish cohort. Methods: A total of 31,297 patients who have suffered an AMI, mean age 62.4 ± 4 years, were
Deep learning has the potential to drastically increase the accuracy and efficiency of prostate cancer diagnosis, which would be of uttermost use. Today the diagnosis is determined manually from H&E stained specimens using a light microscope. In this paper several different approaches based on convolutional neural networks for prostate cancer classification are presented and compared, using th
Recombinant adeno-associated virus serotype 2 (rAAV2) vector has been widely employed for gene therapy. Recent progress suggests that the new serotypes of AAV showed a better performance than did AAV2 in normal tissues. Here, we evaluate the potential role of human vascular endothelial growth factor (VEGF) gene transfer using rAAV vector pseudotyped with serotype I capsid proteins (rAAV1) in the t
The search for new cancer biomarkers is essential for fundamental research, diagnostics, as well as for patient treatment and monitoring. Whereas most cancer biomarkers are biomolecules, an increasing number of studies show that mechanical cues are promising biomarker candidates. Although cell deformability has been shown to be a possible cancer biomarker, cellular forces as cancer biomarkers have
BACKGROUNDThe accuracy of estimation of kidney function with the use of routine metabolic tests, such as measurement of the serum creatinine level, has been controversial. The European Kidney Function Consortium (EKFC) developed a creatinine-based equation (EKFC eGFRcr) to estimate the glomerular filtration rate (GFR) with a rescaled serum creatinine level (i.e., the serum creatinine level is divi
Malawi Polyomavirus Is a Prevalent Human Virus That Interacts with Known Tumor Suppressors Christian Berrios,a,b Joonil Jung,c Blake Primi,d,e Michael Wang,f Chandrasekhar Pedamallu,a,c Fujiko Duke,a,c Christina Marcelus,a Jingwei Cheng,a,g Robert L. Garcea,d,e Matthew Meyerson,a,c,h James A. DeCaprio,a,b,g the TEDDY Study Group Department of Medical Oncology, Dana-Farber Cancer Institute, Boston,
https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-11/38%2006032016_679_38_Berrios_JVirology_2014.pdf - 2026-07-09
The emerging notion of hematopoietic stem and progenitor cells (HSPCs) as a low-primed cloud without sharply demarcated gene expression programs raises the question on how cellular-fate options emerge and at which stem-like stage lineage priming is initiated. Here, we investigate single-cell chromatin accessibility of Lineage-, cKit+, and Sca1+ (LSK) HSPCs spanning the early differentiation landsc
This longitudinal study examined the relationship between flexibility-activity and blood-pressure (BP) change among older adults in Japan. Our study included 452 older adults who took part in our survey in both 2012/2013 and 2017/2018. The seated systolic blood pressure (SBP) and diastolic BP (DBP) were measured both at baseline and at the 5 years follow-up. The frequencies of the different physic
Integration of fiber modification step with a modern pulp mill is a resource efficient way to produce functional fibers. Motivated by the need to integrate polymer adsorption with the current pulping system, anion-specific effects in carboxymethylcellulose (CMC) adsorption have been studied. The QCM-D adsorption experiments revealed that CMC adsorption to the cellulose model surface is prone to an
AIMS: To describe the level of physical activity 6 months after an out-of-hospital cardiac arrest (OHCA) and to explore potential risk factors of a low level of physical activity.METHODS: Post-hoc analyses of the international multicentre Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac arrest (TTM2) trial. At 6 months, survivors at 61 sites in Europe, Australia and
Background: Compared to negative experiences and ill health, little attention has been paidto positive experiences connected to being transgender and gender diverse (TGD).Aim: The aim of the current study was to explore TGD people’s positive experiences in depth.Methods: In total, 33 TGD people were interviewed. Transcripts were analyzed using reflexivethematic analysis.Results: Results show that
As found in the health studies literature, the levels of climate association between epidemiological diseases have been found to vary across regions. Therefore, it seems reasonable to allow for the possibility that relationships might vary spatially within regions. We implemented the geographically weighted random forest (GWRF) machine learning method to analyze ecological disease patterns caused
Grön infrastruktur för bevarande av biologisk mångfald Grön infrastruktur för bevarande av biologisk mångfald BECC POLICY BRIEF | 07 · 2020 BECC POLICY BRIEF | 07 · 2020 Grön infrastruktur för bevarande av biologisk mångfald MARIA VON POST, Centrum för miljö- och klimatforskning, Lunds universitet JOHAN EKROOS, Centrum för miljö- och klimatforskning, Lunds universitet JOHANNA ALKAN OLSSON, Centr
https://www.cec.lu.se/sites/cec.lu.se/files/gron_infrastruktur.pdf - 2026-07-09
Microsoft Word - Baskompetenser Uppdat 20-03-11.docx Baskompetenser ordinarie personal Beslutade 2017-09-18 Justerade av Beredningsgruppen för Service & Miljö, 2020-03-11 1. Lunds universitet □ Ha övergripande kännedom om Lunds universitet: strategi och organisation, inkluderat hur organisationen för biblioteken vid Lunds universitet ser ut och fungerar. □ Kunna hänvisa till information på lu.se.
https://www.lub.lu.se/internt/sites/lub.lu.se.internt/files/beslut_baskompetenser.pdf - 2026-07-09
Sida 1 av 44 Rektor REGELVERK Diarienummer STYR 2023/625 Datum 2024-09-19 Lunds universitets universitetsgemensamma regelverk för utbildning på forskarnivå Innehåll 1 Övriga styrdokument med betydelse för utbildningen på forskarnivå .... 3 2 Principer för utbildning på forskarnivå .................................................. 5 3 Inrättande och avveckling av ämne .............................
FOLDER 3 Universitetsbibliotekets utställningskatalog 62 28 Universitetsbiblioteket, Lunds universitet Box 3, 221 00 LUND UB Media. ISSN 0281-3823, LULID/LIBR - 1550 16 september - 4 december 2011 Bilder och texter massproducerades i Kina 1000 år före Gutenberg. I vår tid sköljer informationen över oss som texter, bilder och ljud i en så rik mångfald att vi knappast kan värja oss. I begynnelsen va
https://www.ub.lu.se/en/sites/ub.lu.se.en/files/2011_trycktekniker.pdf - 2026-07-09
