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In a double blind randomised multicentre study the effect of intravenous clodronate plus hydration was compared with placebo plus hydration in the treatment of hypercalcaemia in breast cancer patients with bone metastases. The patients were treated either with hydration plus clodronate 300 mg/day or hydration plus placebo, up to 7 days or until serum ionised calcium was below 1.4 mmol/l. 25 patien
OBJECTIVE: Although fear of birth is common during pregnancy and childbirth, the best treatment for fear of birth in clinical care remain unclear. Strong evidence suggests that continuity models of midwifery care can benefit women and birth outcomes, though such models are rare in Sweden. Because women with fear of birth could benefit from such models, the aim of this qualitative study was to exam
Purpose: To conduct a systematic review and meta-analysis of quality of life (QoL) outcomes for people with serious mental illness living in three types of supported accommodation. Methods: Studies were identified that described QoL outcomes for people with serious mental illness living in supported accommodation in six electronic databases. We applied a random-effects model to derive the meta-ana
Purpose: Choline is an essential nutrient for fetal and infant growth and development. Parenteral nutrition used in neonatal care lack free choline but contain small amounts of lipid-bound choline in the form of phosphatidylcholine (PC). Here, we examined the longitudinal development of serum free choline and metabolically related compounds betaine and methionine in extremely preterm infants and h
The aim was to explore informal carers’ perceptions of supporting the everyday life of a relative who has a psychiatric disability and resides in supported housing (SH). A qualitative study based on interviews with 12 informal carers was performed, and the data was analyzed with qualitative content analysis. The theme “Navigating in a misty landscape when striving to support a relative with a psyc
Background Coronavirus disease 2019 (COVID-19) is a rapidly spreading disease that has caused extensive burden to individuals, families, countries, and the world. Effective treatments of COVID-19 are urgently needed. Methods and findings This is the first edition of a living systematic review of randomized clinical trials comparing the effects of all treatment interventions for participants in all
Solar energy simulations are used to quantify the potential of the passive use (daylight, solar gains) and the active use (photovoltaics and solar thermal) of solar energy. The simulations can be performed at different scales e.g. buildings, neighbourhoods and cities, with different requirements on the data. For example, for the neighbourhood simulations we need simplified building geometries that
Substance P (SP) and calcitonin gene-related peptide (CGRP) have both been considered potential drug candidates in migraine therapy. In recent years, CGRP receptor inhibition has been established as an effective treatment, in particular as a prophylactic for chronic migraine. Curiously, inhibition of neurokinin receptor 1 (NK1R) failed to alleviate acute migraine attacks in clinical trials, and th
Light dark matter is a hypothesized form of dark matter in the 1 MeV to 1 GeV mass range. The Light Dark Matter eXperiment (LDMX) is an upcoming experiment to test the existence of light dark matter, by colliding an electron beam with a tungsten target and assembling a set of events that potentially indicate the existence of light dark matter. The three main detector components of the LDMX are a s
Popular Abstract in English Modern standard written Chinese has two common object markers, 把 ba and 将 jiang, both of which mark a direct object preceding the verb. Both markers appear to have been widely used in the spoken language of the Tang dynasty but the actual distribution is not entirely clear. Today jiang has disappeared from the dialects and subdialects of northern China and it is mainly Modern standard written Chinese has two common object markers, 把 ba and 将 jiang, both of which mark a direct object preceding the verb. Both markers appear to have been widely used in the spoken language of the Tang dynasty but the actual distribution is not entirely clear. Today jiang has disappeared from the dialects and subdialects of northern China and it is mainly used in the Yue dialect (Can
The notion of corporate violations of human rights is gaining ground. Using an inductive method, this report explores the level of responsibility of multinational enterprise for violations of human rights law committed by business partners and affiliates, i.e. the ''imputability''. The topic is important as the ability to reconstruct the organizational structure provides corporate
Following the Bosman verdict from the ECJ in 1995, FIFA, the governing body of football, had to change its rules for the status and transfer of players to bring them in line with EC law. With the threat of an outright prohibition decision against the international transfer system under the EC Competition rules, FIFA reached an agreement with the Commission, in March 2001, on the principles for the
Participation of Civil Society Organisations (CSOs) has been greatly promoted by the European Union (EU) and many CSOs in social policy sphere in particular have increasingly gained their participatory venues and consultative status vis-a-vis EU institutions since the 90’s. However, their expected role to bring even the most marginalised groups’ voice into European policy making process poses a qu
This article deals with the active safety of a automobile and how to make use of microwave radar sensor to detect and anticipate a threat in the sensor’s field of vision.
The Canadian Arctic currently faces changing coastlines due isostatic rebound and climate change-driven sea-levels rising. This thesis seeks to answer how local coastlines will change over time under different Representative Concentration Pathway (RCP) scenarios, where errors in modelled coastlines come from, and how much of an impact isostatic rebound has on sea-levels compared to climate-change
Swedish office buildings of the 60’s present at least 27% higher heating demand than from the current standards foreseen. This underlines their need for energy renovation. Meanwhile, office buildings are occupied during daytime, thus internal and solar gains are in phase. Consequently, such buildings could experience overheating problems. A seasonal adaptable envelope, such as a ventilated double
Accurate wireless channel models are crucial to simulate the effect of radio wave propagation in a channel on wireless communication systems. By calculating physical processing effects that signal undergoes while traveling from transmitter to the receiver, channel models help to analyze performance of wireless systems. State of the art channel model such as WINNER and COST 2100 are able to model t
