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Objective: Data remain divergent regarding the activational effects of endogenous hormones on adult cognitive function. We examined the association between cognition, hormones and androgen receptor (AR) CAG repeat length in a large cohort of men. Design: Community-based, cross-sectional study of 3369 men aged 40-79 years. Methods: Cognition tests were the Rey-Osterrieth Complex Figure, Camden Topo
High-resolution laser-spectroscopy measurements of hyperfine structure and isotope shifts were performed for the 6snd 1 D 2 sequence of Ba-I in the regionn=12–24. Stepwise laser excitations of a collimated atomic beam were used. A strong influence on the hyperfine structure is observed at the perturbation atn=14, caused by interaction with the 5d7d configuration. Whereas the isotope shift for the
Highly sensitive biosensors were developed for environmental and medical applications. The biosensors were based on bioengineered proteins as biorecognition elements coupled to a highly sensitive capacitive transducer. Heavy metal binding proteins like the metallothionein SmtA, regulatory protein MerR, periplasmic protein MerP and the synthetic phytochelatin EC20 were used for designing, construc
Vehicular networks bring new ways of viewing road traffic management and safety applications. For the first time, it will be possible for vehicles to exchange information and build fine-grained knowledge about the current situation, estimating risks and adapting their driving. Central to these applications is the need to exchange information in a highly dynamic environment, building a view of the
Sensing and manipulating living cells using vertical nanowire devices requires a complete understanding of cell behavior on these substrates. Changes in cell function and phenotype are often triggered by events taking place at the plasma membrane, the properties of which are influenced by local curvature. The nanowire topography can therefore be expected to greatly affect the cell membrane, emphas
AIM: SYT11 and SYT13, two calcium-insensitive synaptotagmins, are downregulated in islets from type-2 diabetic donors, but their function in insulin secretion is unknown. To address this, we investigated the physiological role of these two synaptotagmins in insulin secreting cells.METHODS: Correlations between gene expression levels were performed using previously described RNA-seq data on islets
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On-Going Change in English Modality: Emancipation Through Frequency The English modal expressions BE going to, HAVE got to, and want to are often contracted to gonna, gotta, and wanna in spoken language. These contracted forms have gained both in frequency and conventionality in recent times.In this article, I present an investigation into the status of the contractions between phonetic reduction
