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Hydraulic balancing is key to ensure proper operation of the heating system. When the heating system is not hydraulically balanced, heat is unevenly distributed across dwellings resulting in a wide temperature spread, overheating, and consequently, wastage of energy. In this paper, we study to which extent hydraulic imbalance affects the thermal energy demand of buildings. Furthermore, key variabl
Sensitive detection of short nucleic acids is used to identify viral and bacterial diseases, detect biomarkers of cancer, as well as in gene expression studies. Currently available techniques such as PCR, electrochemical detection and SPR are typically costly and often require amplification of the DNA. Here, we demonstrate a sensing system for picomolar detection of short single-stranded DNA by fl
INTRODUCTION: Autoantibodies against insulin (IAA) are early appearing markers of autoimmunity against the pancreatic islet beta cells and predict progression to type 1 diabetes if additional islet autoantibodies also develop. It is still controversial if proinsulin rather than insulin is the primary autoantibody.METHODS: The aim of the present study was to compare the half-maximal concentration (
INTRODUCTION: Early detection of Alzheimer's disease (AD) is critical for timely intervention as disease-modifying treatments emerge. Speech-based digital biomarkers offer scalable options for remotely capturing speech-derived functional changes associated with early cognitive decline, but validation across real-world populations remains limited.METHODS: We evaluated the speech biomarker for cogni
Metastable cubic tin(II) sulfide (π-SnS) is an earth-abundant semiconductor whose three-dimensionally bonded chiral lattice may overcome the short minority-carrier lifetime of orthorhombic SnS while maintaining a near-ideal bandgap for tandem photovoltaics. Despite its promise, ultrafast carrier cooling and recombination mechanisms over illumination density remain poorly constrained. We use core-l
Obesity is a key contributor to heart failure, driving increased morbidity, mortality, and healthcare costs. This association is supported by multiple pathophysiological mechanisms and consistent epidemiological evidence, particularly not only in heart failure with preserved ejection fraction (HFpEF), but also in heart failure with reduced ejection fraction (HFrEF). Given the rising prevalence of
The thesis examines the truth and reconciliation commission in South Africa and its possibilities to act as a vehicle in the process of consolidating democracy. The norms and values that can be found in the principles and practices of the commission are scrutinized, and the means of presenting this norms to the public is also looked into. The issue of how to deal with the human rights violations o
Following the Bosman verdict from the ECJ in 1995, FIFA, the governing body of football, had to change its rules for the status and transfer of players to bring them in line with EC law. With the threat of an outright prohibition decision against the international transfer system under the EC Competition rules, FIFA reached an agreement with the Commission, in March 2001, on the principles for the
Football supporters’ violence in Sweden is a current societal issue, which lacks experimental investigations. The current study aims to address this gap by investigating social and cognitive factors in order to better understand the mechanisms behind legitimation of violence towards supporters of the opposing team (the out-group). A football supporter and a social science student samples answered
Introduction: There is a need for risk stratification of emergency department (ED) chest pain patients. The Global Registry of Acute Coronary Events risk score (GRACE RS) predicts adverse events in patients with confirmed acute coronary syndrome (ACS), and has been validated on unselected ED patients with chest pain. Clinical gestalt is the unstructured overall clinical assessment, based on the ph
Denna uppsats, som är skriven på kandidatnivå vid företagsekonomiska institutionen vid Lunds universitet, behandlar användandet av konsulter. Det användande som uppsatsen är riktad mot är svenska företagsledningars användande av strategi- och organisationskonsulter. Uppsatsen försöker inte komma fram till om konsulter är bra eller dåliga. Istället försöker den hitta lösningar för företagsledningar
Världen är för närvarande på väg mot 3°C av global uppvärmning pga globala koldioxidutsläpp. Kunskapen som krävs för att minska utsläppen existerar, men de radikala sociala och politiska förändringar som behövs sker hittills inte snabbt nog. Nuvarande politiska och ekonomiska paradigm hyllar koldioxidprissättning som antingen den enda lösningen, alternativt som en del av lösningen. Denna uppsats tThe world is currently heading for 3°C of global warming due to global excessive carbon emissions, and while science is producing the knowledge necessary to combat it, the radical change needed is not coming fast enough. Current political and economic paradigms hail carbon pricing as either the, or part of the solution to our carbon emissions problem. This thesis looks at the available (although l
Immunotherapy aims to enhance the immune system’s response to cancer. Different immunotherapies exist, such as cytokine therapies and immune checkpoint inhibitors. The FDA has approved immunomodulatory drugs, such as Proleukin, a recombinant IL-2 cytokine, Nivolumab, and Avelumab, which are immune checkpoint inhibitors. However, these drugs lead to side effects in patients known as immune-related
Following the collapse of socialism in 1989, Eastern European countries experienced rapid socio-spatial reorganization causing a significant loss of urban greenspace (UGS). Greenspaces provide socio-environmental benefits, making them a crucial component of urban sustainability. This study explores the development of greenspace in Plovdiv (Bulgaria), which serves as a case study to understand disc
While AI is evolving at an unprecedented pace, the legal frameworks of countries around the world still struggle to find the appropriate answer to uniformly deal with AI-related issues. This master thesis would like to discuss one of the legal perspectives that AI technology has drawn attention to recently - its relationship with copyright law. The main point of the thesis is to answer whether im
In this study, over 2000 Milky Way stars were analyzed in the [Mg/Mn] vs [Al/Fe] chemical plane to identify accreted stars. The Milky Way's faster star formation enriches disk stars with iron-peak elements such as Mn and reduces alpha elements like Mg. Accreted stars, originating from slower star formation rate environments, exhibit lower metallicities, reflected in lower [Al/Fe]. The study ev
