Filetype
The first European Stroke Organization (ESO) standard operating procedure (SOP) published in 2015 aimed at the implementation the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology to provide evidence-based guidelines for stroke management. This second ESO-SOP is aiming at further increase of the practicability of ESO guidelines and its technical implications. A
The concept of Partially Premixed Combustion (PPC) in internal combustion engines has shown to yield high gross indicated efficiencies, but at the expense of gas exchange efficiencies. Most of the experimental research on partially premixed combustion has been conducted on compression ignition engines designed to operate on diesel fuel and relatively high exhaust temperatures. The partially premix
Background: In recent years, emphasis has been put on that medical student should demonstrate pre-practice/pre-registration core procedural skills to ensure patient safety. Nonetheless, the formal teaching and training of basic suturing skills to medical students have received relatively little attention and there is no standard for what should be tested and how. The aim of this study was to devel
Physiological adaptation through acclimation is one way to cope with temperature changes. Biochemical studies on acclimation responses in ectotherms have so far mainly investigated consequences of short-term acclimation at the adult stage and focussed on adaptive responses. Here, we assessed the consequences of rearing Drosophila melanogaster at low (12°C), benign (25°C) and high (31°C) temperatur
We investigate the relation between crystal stacking faults in individual wurtzite InAs and GaAs nanowires and the intensity of the forbidden longitudinal optical (LO) phonon mode in the Raman spectra. Micro-Raman spectroscopy and transmission electron microscopy are combined on the same individual nanowires to evaluate the LO mode intensity as a function of the stacking fault density. A clear inc
An important part of the justification process is assessment of the radiation risks caused by exposure of a patient during examination. The authors developed official national methodology both for medical doctors and sanitary inspectors called ‘assessmentof radiation risks of patients undergoing diagnostic examinations with the use of ionizing radiation’. The document addressespatients of various
Xyloside analogues with substitution of the endocyclic oxygen atom by sulfur or carbon were investigated as substrates for β-1,4-galactosyltransferase 7 (β4GalT7), a key enzyme in the biosynthesis of glycosaminoglycan chains. The analogues with an endocyclic sulfur atom proved to be excellent substrates for β4GalT7, and were galactosylated approximately fifteen times more efficiently than the corr
A socially mixed population is a politically stated ambition in Stockholm, the capital of Sweden. By providing a variety of tenure alternatives – i.e. rental and ownership housing – throughout all neighborhoods it is presumed this objective could be at least partially fulfilled. Since current tenure proportions display a weak balance in many neighborhoods it could consequently be assumed that gove
Background: Patients with synchronous colorectal liver metastases (sCRLM) are increasingly operated with liver resection before resection of the primary cancer. The aim of this study was to compare outcomes in patients following the liver-first strategy and the classical strategy (resection of the bowel first) using prospectively registered data from two nationwide registries. Methods: Clinical, p
One year ago, we discovered a new family of insect RYamide neuropeptides, which has the C-terminal consensus sequence FFXXXRYamide, and which is widely occurring in most insects, including the fruitfly Drosophila melanogaster and the red flour beetle Tribolium castaneum (F. Hauser et al., J. Proteome Res. 9 (2010) 5296-5310). Here, we identify a Drosophila G-protein-coupled receptor (GPCR) coded f
What explains variation in military spending? Conventional wisdom suggests that states arm because of either foreign threats or domestic political institutions. The literature treats these factors as distinct and separate (Nordhaus et. al. 2012, Fordham and Walker 2005, Goldsmith 2003). Less attention is given to how states with different internal constraints respond to similar circumstances. This
Analyses of foraminiferal assemblages have often been implemented on dry samples, which are easy to split. In some cases, the wet-picking method is preferred as it allows the preservation of more foraminiferal forms and facilitates the picking of live foraminifera. However, the increased execution time needed for wet picking may cause micropalaeontologists to refrain from employing it in a routine
The environment of the Tibetan Plateau (TP) is regarded as one of the most sensitive ecosystems of the world. However, investigations on effects caused by global climate change or anthropogenic activities are rare due to its quite remote location. This thesis deals with various aspects of the carbon and water cycle within ecological and hydrological studies that can be assessed by measurements of
When reconstructing combined defects of the cervical spine and the posterior pharyngeal wall the goals are bone stability along with continuity of the aerodigestive tract. We present a case of a patient with a cervical spine defect, including C1 to C3, associated with a posterior pharyngeal wall defect after excision of a chordoma and postoperative radiotherapy. The situation was successfully solv
Microtubule-disturbing drugs inhibit lysosomal trafficking and induce lysosomal membrane permeabilization followed by cathepsin-dependent cell death. To identify specific trafficking-related proteins that control cell survival and lysosomal stability, we screened a molecular motor siRNA library in human MCF7 breast cancer cells. SiRNAs targeting four kinesins (KIF11/Eg5, KIF20A, KIF21A, KIF25), my
Background: Norovirus is frequently introduced to the hospital and is a frequent cause of hospital outbreaks. Recognition of the factors that facilitate or impede norovirus transmission is an important step to effectively prevent hospital outbreaks. Aim: To investigate risk factors for norovirus outbreaks in hospital settings. Methods: Clinical data, ward setting, and norovirus genotype were colle
Witnessing violence toward a caregiver during childhood is associated with negative impact on children's health and development, and there is a need for effective interventions for children exposed to intimate partner violence in clinical as well as in community settings. The current effectiveness study investigated symptom reduction after participation in two established group interventions (one
Bicelles are tunable disk-like polymolecular assemblies formed from a large variety of lipid mixtures. Applications range from membrane protein structural studies by nuclear magnetic resonance (NMR) to nanotechnological developments including the formation of optically active and magnetically switchable gels. Such technologies require high control of the assembly size, magnetic response and therma
In the era of the Internet of Things and social media; communities, governments, and corporations are increasingly eager to exploit new technological innovations in order to track and keep up to date with important new events. Examples of such events include the news, health related incidents, and other major occurrences such as earthquakes and landslides. This area of research commonly referred t
