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This study characterizes the high-fat diet-fed mouse as a model for impaired glucose tolerance (IGT) and type 2 diabetes. Female C57BL/6J mice were fed a high-fat diet (58% energy by fat) or a normal diet (11% fat). Body weight was higher in mice fed the high-fat diet already after the first week, due to higher dietary intake in combination with lower metabolic efficiency. Circulating glucose incr
Language cultivation and grammars in Sweden and Denmark 1550-1800.
Dependence on fossil fuel is an issue for the many countries, it is particularly challenging for Small Island Developing States. Reliance on fossil fuel is becoming for many SIDS an economic burden. Due to the constant fluctuation in oil prices which leads to high fuel prices, high cost of living, and high electricity bills when the price of this commodity is high. This results in constant pressur
In the present study, wild type and three mutants of pyranose 2-oxidase (PyOx-WT, PyOx-MT1, PyOx-MT2, PyOx-MT3), which showed improved properties for D-galactose oxidation, were investigated for their oxidising ability when immobilised on graphite electrodes. Four different flexible Os polymers with formal potentials ranging between −0.140 and 0.270 V vs. Ag|AgCl0.1 M KCl were applied together wit
Searches for the exclusive decays of the Higgs and Z bosons into a J/ψ, ψ(2S), or ϒ(nS) (n=1,2,3) meson and a photon are performed with a pp collision data sample corresponding to an integrated luminosity of 36.1fb−1 collected at s=13TeV with the ATLAS detector at the CERN Large Hadron Collider. No significant excess of events is observed above the expected backgrounds, and 95% confidence-level up
The rapid growth of cities requires effective management of transport demand and restructuring of transport systems to address the needs of growing urban populations in an environmentally, socially and economically sustainable way. In recent years, car sharing has emerged as an alternative to owning cars in cities, which has potential to bring environmental gains and address social considerations.
INTRODUCTION: Hip and knee osteoarthritis is a leading cause of disability worldwide. Currently, the course of deterioration in pain and physical functioning in individuals with osteoarthritis is difficult to predict. Factors such as socioeconomic status and comorbidity contribute to progression of osteoarthritis, but clear associations have not been established. There is a need for early identifi
An international panel of experts representing 17 European countries and Israel convened to discuss current needs and future developments in BRCA testing and counselling and to issue consensus recommendations. The experts agreed that, with the increasing availability of high-throughput testing platforms and the registration of poly-ADP-ribose-polymerase inhibitors, the need for genetic counselling
In this thesis, I compare the economic development between one democracy, India, and one autocracy, China. The idea is to see whether democracy has anything to do with economic development in terms of growth and welfare. To my disappointment, I have found that democracy does not have a big impact on economic development. Instead, it seems that the economical development depends on the economical p
Commercial sexual exploitation of Children and Adolescents (CSEC) is an increasing problem all over the world and especially in developing countries with growing tourist industries. In these countries CSEC and Child Sex Tourism have become two often closely connected problems. In Costa Rica there are many NGOs and governmental institutions working with these problems through prevention, attention
Climate change can raise average temperatures and humidity and induce more frequent and stronger extreme weather events. This intensifies the need for studies on indoor climate and energy use in livestock buildings as it will affect animal welfare and farmers’ economy in terms of production, energy demand and needed investments. The aim of this review was to identify knowledge gaps and the need fo
This chapter critically examines a number of ethical dilemmas at stake for professionals working with refugee children and families in Denmark within the field of early childhood education. While national guidelines promote diversity by framing cultural differences as valuable resources, integration policies often result in efforts aimed at assimilation. The chapter explores how everyday ethical j
Objectives To study the effect of a progressively enhanced rest–shade–hydration–hygiene (RSHH) intervention on kidney injury and inflammation biomarkers, and rates of clinical acute kidney injury (AKI) in Nicaraguan sugarcane workers with a very high rate of chronic kidney disease of non-traditional origin (CKDnt). Methods We analysed serum creatinine and C-reactive protein (CRP) and leukocyturia
Epilepsy affects approximately 50 million people worldwide, and over 30% of patients are considered treatment resistant to currently available anti-seizure drugs. Neuropeptide Y (NPY) has been shown to inhibit excitatory synaptic transmission in hippocampal slices from human epilepsy patients via Y2 receptors (Y2Rs), and overexpression of NPY and/or Y2R in the hippocampus reduces seizures in roden
AimsDyspnoea accounts for nearly 5% of emergency department (ED) visits. Our aim was to describe the in-hospital and long-term outcomes of patients admitted to the ED for dyspnoea, based on their underlying aetiology, and to determine if prognosis varies according to the hospitalization setting.MethodsWe analyzed 18 903 consecutive patients (48% male, average age 73 years) hospitalized after an ED
Accurate, high-resolution global land use and land cover (LULC) mapping is crucial for environmental monitoring, but remains challenging when relying solely on multispectral data. Most existing global LULC mapping studies rely exclusively on multispectral observations, and even those that incorporate synthetic aperture radar (SAR) data often fail to fully exploit the information it provides. SAR p
Cryo-scanning electron microscopy (CryoSEM) permits the preparation and detailed imaging of bulky samples while keeping them in a hydrated state. For plant biology, cryofractures give information on cell ultrastructure and tissue organisation within a much larger context that is the whole organ or organism. To date, a method to locate fluorescence reporters on the cryofracture has not been reporte
