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Antikroppar och skillnad mellan typ 1- och typ 2-diabetes

henric borg Vid Typ 1 diabetes mellitus (insulinberoende, [ungdoms]) förlorar kroppen förmågan att tillverka insulin, det hormon som styr upptaget av socker i kroppens celler. Insulinet bildas av bukspottskörtelns hormonproducerande betaceller, och Typ 1 diabetes orsakas av att dessa celler skadas och förstörs. Denna skadeprocess anses idag i de flesta fall förmedlas av kroppens eget immunsystem,

https://www.diabetesportalen.lu.se/fran-labbet-till-apotekshyllan/avhandlingar/2002/antikroppar-och-skillnad-mellan-typ-1-och-typ-2-diabetes - 2026-05-29

Exploring the Functional Landscape of the p53 Regulatory Domain : The Stabilizing Role of Post-Translational Modifications

This study focuses on the intrinsically disordered regulatory domain of p53 and the impact of post-translational modifications. Through fully atomistic explicit water molecular dynamics simulations, we show the wealth of information and detailed understanding that can be obtained by varying the number of phosphorylated amino acids and implementing a restriction in the conformational entropy of the

Sociodemographic characteristics and COVID-19 testing rates : spatiotemporal patterns and impact of test accessibility in Sweden

BACKGROUND: Diagnostic testing is essential for disease surveillance and test-trace-isolate efforts. We aimed to investigate if residential area sociodemographic characteristics and test accessibility were associated with Coronavirus Disease 2019 (COVID-19) testing rates.METHODS: We included 426 224 patient-initiated COVID-19 polymerase chain reaction tests from Uppsala County in Sweden from 24 Ju

Diabetic status and the performances of creatinine- and cystatin C–based eGFR equations

Background. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinine and the European Kidney Function Consortium (EKFCcrea ) equation is the most validated in Europe. More recently, cystatin C has been proposed as a biomarker. We studied the performances of the EKFC equations in a large cohort of subjects according to

Prostate specific antigen concentration at age 60 and death or metastasis from prostate cancer : Case-control study

Objective: To determine the relation between concentrations of prostate specific antigen at age 60 and subsequent diagnosis of clinically relevant prostate cancer in an unscreened population to evaluate whether screening for prostate cancer and chemoprevention could be stratified by risk. Design: Case-control study with 1:3 matching nested within a highly representative population based cohort stu

Physical exercise, immune response, and susceptibility to infections—current knowledge and growing research areas

This review presents state-of-the-art knowledge and identifies knowledge gaps for future research in the area of exercise-associated modifications of infection susceptibility. Regular moderate-intensity exercise is believed to have beneficial effects on immune health through lowering inflammation intensity and reducing susceptibility to respiratory infections. However, strenuous exercise, as perfo

Predicting Sensitivity to Adverse Lifestyle Risk Factors for Cardiometabolic Morbidity and Mortality

People appear to vary in their susceptibility to lifestyle risk factors for cardiometabolic disease; determining a priori who is most sensitive may help optimize the timing, design, and delivery of preventative interventions. We aimed to ascertain a person's degree of resilience or sensitivity to adverse lifestyle exposures and determine whether these classifications help predict cardiometabolic d

A regression discontinuity analysis of the social distancing recommendations for older adults in Sweden during COVID-19

BACKGROUND: This paper investigates the impact of a non-mandatory and age-specific social distancing recommendation on isolation behaviors and disease outcomes in Sweden during the first wave of the COVID-19 pandemic (March to July, 2020). The policy stated that people aged 70 years or older should avoid crowded places and contact with people outside the household.METHODS: We used a regression dis

Changes in perceived parental self-efficacy after a Child-Centred Health Dialogue about preventing obesity

Aim: This randomised controlled trial evaluated changes in parental self-efficacy and children's weight, after a Child-Centred Health Dialogue about preventing obesity. Methods: We randomly assigned 37 Child Health Centres in Skåne county Sweden to provide usual care or the dialogue intervention. They included centres from high and low socioeconomic areas. The outcomes were changes in parental sel

Nano-Infrared Imaging of Primary Neurons

Alzheimer’s disease (AD) accounts for about 70% of neurodegenerative diseases and is a cause of cognitive decline and death for one-third of seniors. AD is currently underdiagnosed, and it cannot be effectively prevented. Aggregation of amyloid-β (Aβ) proteins has been linked to the development of AD, and it has been established that, under pathological conditions, Aβ proteins undergo structural c

Pre-diagnostic meat and fibre intakes in relation to colorectal cancer survival in the European Prospective Investigation into Cancer and Nutrition

Improvements in colorectal cancer (CRC) detection and treatment have led to greater numbers of CRC survivors, for whom there is limited evidence on which to provide dietary guidelines to improve survival outcomes. Higher intake of red and processed meat and lower intake of fibre are associated with greater risk of developing CRC, but there is limited evidence regarding associations with survival a

Single-cell multiomics of human fetal hematopoiesis define a developmental-specific population and a fetal signature

Knowledge of human fetal blood development and how it differs from adult blood is highly relevant to our understanding of congenital blood and immune disorders and childhood leukemia, of which the latter can originate in utero. Blood formation occurs in waves that overlap in time and space, adding to heterogeneity, which necessitates single-cell approaches. Here, a combined single-cell immunopheno

HIV-2 mediated effects on target and bystander cells induce plasma proteome remodeling

Despite low or undetectable plasma viral load, people living with HIV-2 (PLWH2) typically progress toward AIDS. The driving forces behind HIV-2 disease progression and the role of viremia are still not known, but low-level replication in tissues is believed to play a role. To investigate the impact of viremic and aviremic HIV-2 infection on target and bystander cell pathology, we used data-indepen

200212. deu. schedule syllabus

200212. D€. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start. # Session Required readings Session focus Module 1: Setting the stage 1 Money today, theory and practice April 20, 13.00-16.00 Anders Ögren, Ester Barinaga, Paul Stankovski & Christian Gehrmann Readings: • Werner, R.2014. Can

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200212._deu._schedule_syllabus.pdf - 2026-05-30

Kurser Biologiska Institutionen 24-25

Kurserna omfattar 15 hp om inget annat anges Obs! Listan är preliminär jan, 2024 Sommar, 2025 Period 1: 2/9 - 1/11 Period 2: 4/11- 17/1 Period 1: 20/1 - 21/3 Period 2: 24/3 - 5/6 Cell- och mikrobiologi BIOA10 Genetik och evolution BIOA11 Botanik och zoologi BIOB10 Djurs beteende BIOF08, E, läggs ner V25 BIOF03 Floristik-forts. 7,5 hp Ekologi BIOC13 Human- och zoofysiologi BIOC11 Molekylärbiologi M

https://www.biologyeducation.lu.se/sites/biologyeducation.lu.se/files/2024-03/Kurser_Biologiska_Institutionen_24-25.pdf - 2026-05-30

GEOA02 Kursanalys HT 2025

Kursvärdering GEOA02, HT 2025 På kursutvärderingen var 29 av 34 studenter närvarande, samt Ulf Söderlund, Mats Eriksson och Karl Ljung. Utvärderingen skedde dels genom öppen diskussion där kursens struktur och olika moment behandlades och dels genom anonyma svar på specifika frågor kring kursen. Anteckningar togs av Mats Eriksson. Kursvärderingen har sammanställts av Ulf Söderlund, tillika kursans

https://www.geologi.lu.se/sites/geologi.lu.se/files/2025-11/GEOA02%20kursanalys%20HT%202025.pdf - 2026-05-30

Mercado lina

-- .-/, MODELLING RAINFOREST CARBON AND WATER DYNAMICS -Comparison of different land-lise systems following removal of primary forest in the Colombian Amazon- Lina Maria Mercado Montoya LUNDS UNIVERSITET Master' s thesis Lund University Master' s Programme in Environmental Science Address, Lina Maria Mercado M, Carrera 31N 17 S 61. Medellin, Colombia e-mail: linamercado@hotmai1.com Lund, Sweden No

https://www.lumes.lu.se/sites/lumes.lu.se/files/mercado_lina.pdf - 2026-05-30

200224. deu. schedule syllabus

200224. D€. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start. # Session Required readings Session focus Module 1: Setting the stage 1 Money today, theory and practice April 20, 13.00-16.00 Anders Ögren, Ester Barinaga, Paul Stankovski & Christian Gehrmann Readings: • Werner, R.2014. Can

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200224._deu._schedule_syllabus.pdf - 2026-05-30

200407. deu blended. schedule syllabus

200407. D€ blended. schedule syllabus Doctoral School Agenda 2030 Digital Monies for a Sustainable Future The syllabus is preliminary and subject to changes till the course’s start.
 The course is taught mainly online, but ends with a one-and-a-half physical workshop at Lund University. Deadline for course registration: August 14. For registering, contact Charlina Lunvald (charlina.lunvald@fek.lu.

https://www.sustainability.lu.se/sites/sustainability.lu.se/files/200407._deu_blended._schedule_syllabus.pdf - 2026-05-30