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Given that FLT3 expression is highly restricted on lymphoid progenitors, it is possible that the established role of FLT3 in the regulation of B and T lymphopoiesis reflects its high expression and role in regulation of lymphoid-primed multipotent progenitors (LMPPs) or common lymphoid progenitors (CLPs). We generated a Flt3 conditional knock-out (Flt3fl/fl) mouse model to address the direct role
Lung cancer has several genetic associations identified within the major histocompatibility complex (MHC); although the basis for these associations remains elusive. Here, we analyze MHC genetic variation among 26,044 lung cancer patients and 20,836 controls densely genotyped across the MHC, using the Illumina Illumina OncoArray or Illumina 660W SNP microarray. We impute sequence variation in clas
Parvalbumin- (PV-) containing basket cells constitute perisomatic GABAergic inhibitory interneurons innervating principal cells at perisomatic area, a strategic location that allows them to efficiently control the output and synchronize oscillatory activity at gamma frequency (30–90 Hz) oscillations. This oscillatory activity can convert into higher frequency epileptiform activity, and therefore c
Tyrosine kinase inhibitors (TKIs) are highly effective for the treatment of chronic myeloid leukemia (CML), but very few patients are cured. The major drawbacks regarding TKIs are their low efficacy in eradicating the leukemic stem cells responsible for disease maintenance and relapse upon drug cessation. Herein, we performed ribonucleic acid sequencing of flow-sorted primitive (CD34+CD38low) and
Background Whole-genome sequencing (WGS) of heart transplant recipient- and donor-derived cardiac biopsies may facilitate organ matching, graft failure prediction, and immunotolerance research. The objective of this study was to determine the feasibility of WGS based on formalin-fixed paraffin-embedded endomyocardial biopsies. Methods and results The study included serial donor- and recipient samp
BACKGROUND: Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of lung cancer remains unclear. METHODS: We performed single and combined multiple instrumental variable Mendelian randomization analysis by an inverse-weighted method, in addition to a
Older women make a significant contribution to the labour market yet still experiencenegative workplace impacts. We undertook a rapid review of literature to assess theexperiences of older female workers in the European labour market with the aim toidentify current research gaps. We discuss how current data and future research couldbe utilized to improve the working lives of older women in Europe.
To gain insights into the regulatory mechanisms of hematopoietic stem cells (HSCs), we employed a genome-wide RNAi screen in human cord-blood derived cells and identified candidate genes whose knockdown maintained the HSC phenotype during culture. A striking finding was the identification of members of the cohesin complex (STAG2, RAD21, STAG1, and SMC3) among the top 20 genes from the screen. Upon
BACKGROUND: The discovery of low-frequency coding variants affecting the risk of coronary artery disease has facilitated the identification of therapeutic targets. METHODS: Through DNA genotyping, we tested 54,003 coding-sequence variants covering 13,715 human genes in up to 72,868 patients with coronary artery disease and 120,770 controls who did not have coronary artery disease. Through DNA sequ
Improvements in colorectal cancer (CRC) detection and treatment have led to greater numbers of CRC survivors, for whom there is limited evidence on which to provide dietary guidelines to improve survival outcomes. Higher intake of red and processed meat and lower intake of fibre are associated with greater risk of developing CRC, but there is limited evidence regarding associations with survival a
Centre for Economic Demography Lund University School of Economics and Management P.O. Box 7083 SE-220 07 Lund, Sweden www.ed.lu/publications/Lund-Papers-in-Economic-Demography/ Factors Associated with an Unmet Need for Contraception in the United States, 2002-2017 JOSEPH MOLITORIS LUND PAPERS IN ECONOMIC DEMOGRAPHY 2019:6 Copyright is held by the author(s). Lund Papers in Economic Demography are
https://www.lusem.lu.se/sites/lusem.lu.se/files/2024-07/LPED_2019_6.pdf - 2026-06-07
Microsoft Word - Stavanger OIivia ht18.doc Min utbytestermin i Norge Om jag fick ge dig som snart ska läsa din femte termin på ditt program ett enda råd, så är det att ta chansen att åka iväg på utbyte. Det är en fantastisk möjlighet att framför allt få chansen att växa yttligare som person men också chansen att få utökat kontaktnät, förbättra engelska och bara få chansen att bo i ett annat land.
https://www.ses.lu.se/sites/ses.lu.se/files/stavanger_oiivia_ht18.pdf - 2026-06-07
En gemensam process för långsiktig påverkan Arbetet med att ta fram en hållbarhetsplan inom NextG2Com inleddes med en digital kickoff tillsammans med Vinnova och konsultföretaget AFRY. Syftet var att skapa en gemensam förståelse för hållbarhetsfrågornas betydelse inom centrumets verksamhet och att lägga grunden för ett långsiktigt, strukturerat hållbarhetsarbete.Processen har innefattat följande s
https://www.nextg2com.lu.se/hallbarhetsarbete-inom-nextg2com - 2026-06-07
12 Utbildningsplan Musikerutbildning blockflöjt, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, blockflöjt. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: BLFL. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade utbildningsplanen träder i kraft
https://www.mhm.lu.se/sites/mhm.lu.se/files/nymu_utbildningsplaner_samlingsdokument_blockglojt_kand.pdf - 2026-06-07
4 Utbildningsplan Musikerutbildning symfoniorkesterinstrument, 180 hp – kandidat 1. IDENTIFIKATION Programmets namn och inriktning: musikerutbildning, symfonior- kesterinstrument. Omfattning i högskolepoäng: 180. Nivå: Grundnivå (G). Programkod: KGMUS. Inriktning: SYMF. 2. BESLUTSUPPGIFTER Utbildningsplanen är reviderad och beslutad av konstnärliga fakul- tetsstyrelsen 2017-10-18. Den reviderade u
https://www.mhm.lu.se/sites/mhm.lu.se/files/nymu_utbildningsplaner_samlingsdokument_symf_kand.pdf - 2026-06-07
Development/Plasticity/Repair Striatal Neuron Differentiation from Neurosphere-Expanded Progenitors Depends on Gsh2 Expression Josephine B. Jensen, Anders Björklund, and Malin Parmar Wallenberg Neuroscience Center, Section of Neurobiology, and Lund Strategic Research Center for Stem Cell Biology and Cell Therapy, Lund University, SE-221 84 Lund, Sweden Neural stem and progenitor cells from the em
https://www.real.lu.se/innovation - 2026-06-07
Prevention Celiaki i Skåne Intaget till PreCise avslutas med barn som fötts senast 2024-12-31. Vad är PreCiSe?Barn som i screening visat sig ha de specifika riskgenerna för celiaki (glutenintolerans) kan gå med i PreCiSe, Prevention Celiaki i Skåne, en studie vars syfte är att utvärdera hur man kan förhindra eller fördröja att barn med högre risk utvecklar celiaki.Den enda behandlingen som finns i
https://www.gppad.lu.se/vara-studier/precise - 2026-06-07
MILJÖVETENSKAP Preliminärt schema 180620 Kurs: Grundkurs i Miljövetenskap MVEA01, HT2018 Kursansvarig: Katarina Hedlund Lärare: Åsa Knaggård (ÅK), Helena Hanson (HH), Hampus Nilsson (HN), Terese Thoni (TT), Ullrika Sahlin (US), William Sidemo Holm (WSH), Katarina Hedlund (KH), Nina Reistad (NR), Jan Johansson (JJ), Christian Alsterberg (CA), Anna Persson (AP), Maria von Post (MP), Martijn van Praa
https://www.cec.lu.se/sv/sites/cec.lu.se.sv/files/prel_schema_mvea01_180620.pdf - 2026-06-07
