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Cell type deconvolution - the computational estimation of cellular composition in bulk tissue samples - is a valuable tool in cancer research for understanding immune infiltration and tissue heterogeneity. Most deconvolution algorithms infer the composition of cell types in bulk samples by modeling the observed expression data as a linear combination of reference expression profiles from each cell
Fourier transform infrared spectroscopy techniques were used to study the kinetics of gas-phase reactions of three lactones, γ-valerolactone (GVL), 2(5H)-furanone (2(5HF) and 3-methyl-2(5H)-furanone (3M2(5H)F) with Cl atoms, OH radicals and O3 respectively. The experiments were performed in a photochemical reactor at a total pressure of 700 Torr at room temperature (298±2 K). Both relative rate an
Through a case study of H&Ms equestrian sponsorship this study aims to investigate the communicative aspects of sports sponsorships targeting a young audience, as well as its impact on the core values of children’s and youth sports in the Swedish society. Furthermore, this study intends to investigate and create further knowledge on how elite athletes are used by commercial businesses in order
This thesis explores the integration of hydrogen and battery energy storage systems as a means to enhance the management of wind and solar power in the pursuit of a greener grid. The objective of the study is to identify the potential benefits and challenges associated with hybrid energy storage systems (HESS) and their role in renewable energy integration. The thesis begins with a literature rev
There is a need to identify leverage points for a broader cultural transformation that addresses the root causes of the nature-climate emergency. Music and art festivals are creative free spaces outside the everyday workings of society that have the potential to plant the seeds of a holistic, sustainable future. I combine prefiguration and the three spheres of transformation in a framework to inve
This master’s thesis explores the sustainability and the circularity of industrial packaging of components for complex electronic products. The research aims to gain insight into the structure of the packaging system between the suppliers and the manufacturers (EMS) and evaluate its circularity to identify the opportunities and challenges for future improvement. The study examines the packaging
This master’s thesis explores the sustainability and the circularity of industrial packaging of components for complex electronic products. The research aims to gain insight into the structure of the packaging system between the suppliers and the manufacturers (EMS) and evaluate its circularity to identify the opportunities and challenges for future improvement. The study examines the packaging fo
Gestures are used in a pragmatic way in interactive contexts such as conversation. Agreement between interlocutors is an ordinary aspect of talk-in-interaction, which is expressed through various types of utterances and gestures. The interlocutors’ status, such as gender and familiarity, may affect both their verbal and non-verbal behavior as previous research has shown. This study investigates th
The polarization observables T,E,P,H, and G in photoproduction of η mesons off protons are measured for photon energies from threshold to W=2400 MeV (T), 2280 MeV (E), 1620 MeV (P,H), or 1820 MeV (G), covering nearly the full solid angle. The data are compared to predictions from the SAID, MAID, JüBo, and BnGa partial-wave analyses. A refit within the BnGa approach including further data yields pr
Phosphodiesterase-5 (PDE5) inhibitors are suggested to have anti-tumor effects and to inhibit surgery-induced immunosuppression. We aimed to explore whether post-diagnostic use of PDE5 inhibitors was associated with a better prognosis among male patients with colorectal cancer (CRC) and the role of open surgery in the association. Here we show that post-diagnostic use of PDE5 inhibitors is associa
Background: Optimal alignment is of utmost importance when treating pediatric patients with craniospinal irradiation (CSI), especially with regards to field junctions and multiple isocenters and techniques applying high dose gradients. Here, we investigated the setup errors and uncertainties for pediatric CSI using different setup verification protocols. Methods: A total of 38 pediatric patients t
Infectious diseases that can be transmitted via air often spread rapidly, sometimes causing large epidemic and pandemic outbreaks. As an increasing number of people live in crowded urban environments, and with frequent and long-distance traveling across the world, infectious diseases can spread even faster. Yet, our knowledge of how much airborne transmission (here defined as aerosol particles <10
The sun is the most important energy source for the Earth’s climate system, however, influences of solar variations on climate are not fully understood. Studying past solar activity can improve our understanding of what role the sun plays in Earth’s climate. Cosmogenic radionuclides, such as 10Be in ice cores, are powerful tools to reconstruct past solar activity before the period of direct telesc
Cross-border regions are characterised by many inherent challenges. Such challenges can include differences in languages, cultures, currencies, markets, labour market conditions, political visions and priorities, governance structures – to name but a few. Greater Copenhagen1 is no different in terms of the challenges it faces as a cross-border region.The aim of this study is to investigate the pos
A typical approach when designing a bio-inspired robot is to simplify an animal model and to enhance the functionality of interest. For hexapod robots, this often leads to a need of supplementary mechanics to become multifunctional. However, a preferable solution is to employ the embodied multifunctional capabilities of the animal as inspiration for robot design. Using this approach, we present a
The global CO2 emissions in 2010 from fossil energy use grew at the fastest rate since 1969. The year 2010 also witnessed that the global oil production did not match the rapid growth in consumption [1]. These recent data further intensify worldwide concerns about greenhouse gas emissions and energy security for a sustained economic development. For a reduced dependence on oil from fossil reserves
Development of methods for Risk and Vulnerability Assessment (RVA) is typically carried out more or less isolated from the practical context in which the method is intended to be used. This means that practical limitations, constraints and challenges are missed, potentially leading to the proposed method is not suited for its intended end-users and giving poor results. Therefore, the aim of this p
The growth of a planetary core by pebble accretion stops at the so-called pebble isolation mass, when the core generates a pressure bump that traps drifting pebbles outside its orbit. The value of the pebble isolation mass is crucial in determining the final planet mass. If the isolation mass is very low, gas accretion is protracted and the
Safeguarding the diversity of natural and semi-natural habitats in Europe is one of the aims set out by the Habitats Directive (Council Directive 92/43/EEC on the conservation of natural habitats and of wild fauna and flora) and one of the targets of the European 2020 Biodiversity Strategy, and is to be accomplished by maintaining a favourable conservation status. To reach this aim a high-level un
