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Whole-exome and whole-genome sequencing (WES, WGS) can generate an unprecedented amount of complex information, making the informed consent (IC) process challenging. The aim of our study was to assess the readability of English IC forms for clinical whole-exome and whole-genome sequencing using the SMOG and Flesch-Kincaid formulas. We analysed 36 forms, most of which were from US providers. The me
In this brief text we look at one instance of how gender norms continue to inform institutional treatment of parents regarding care for children: specifically, at how the exercise of fathers' responsibilities for their children can be discouraged or altogether blocked.
The existing models for the conversion and design of polymer gears are only valid for involute gears. This research was focused on S-gears, a specific type of gear profile which has more favorable contact conditions and greater root thickness when compared to involute gears. S-gears design is currently based on tests, experience, and the use of numerical simulations. Due to the lack of a simple ca
We study shrinking target problems and the set of eventually always hitting points. These are the points whose first n iterates will never have empty intersection with the nth target for sufficiently large n. We derive necessary and sufficient conditions on the shrinking rate of the targets for to be of full or zero measure especially for some interval maps including the doubling map, some quadrat
The Large Intelligent Surface (LIS) concept has emerged recently as a new paradigm for wireless communication, remote sensing and positioning. It consists of a continuous radiating surface placed relatively close to the users, which is able to communicate with users by independent transmission and reception (as a Base Station). Despite of its potential, there are a lot of challenges from an implem
Breast cancer is an important cause of disease-burden and death in women. To prevent over- and undertreatment of breast cancer patients, new prognostic and predictive factors are needed. We aimed to study associations between prognosis and body constitution, genetic factors, and tumor-specific protein levels related to metabolic pathways, and to examine the prognostic impact of statin use and body
We see a potential for ESS to benefit from sharing alarm data for machine learning applications, by establishing data ecosystem. To achieve these goal, ESS must make a strategic decision to pursue data sharing, establish a technical platform to share a digital twin, continue advancing the data ecosystem, and work towards a standardized reference model.
A pulsed millimeter wave radar operating at a frame rate of 144 Hz is utilized to record 2160 scattering signatures of 12 generic hand gestures. Gesture recognition is achieved by machine learning, utilizing transfer learning on a pretrained convolutional neural network. This yields excellent classification results with a validation accuracy of 99.5%, based on a 60% training versus 40% validation
Gaza has several water problems; inefficient water use by the agricultural sector, limited fresh water supply and high water demand, groundwater contamination, seawater intrusion and shortage of electricity. More water and electricity for the future development of Gaza that will give better life; a significant value of water should be added to the Palestinians living in blocked Gaza; more employme
Studies of fully-reconstructed jets in heavy-ion collisions aim at extracting thermodynamical and transport properties of hot and dense QCD matter. Recently, a plethora of new jet substructure observables have been theoretically and experimentally developed that provide novel precise insights on the modifications of the parton radiation pattern induced by a QCD medium. This report, summarizing the
This paper presents the design and features of frequency-selective wallpaper-based on periodic and symmetric metallic hexagons-intended to be attached to standard walls for filtering out 5GHz signals (e.g., IEEE 802.11a systems)without blocking other selected radio communication services (e.g., cellular mobile communication signals). It analyzes the characteristics of the radio channel-as found wi
Metabolic responses to food influence risk of cardiometabolic disease, but large-scale high-resolution studies are lacking. We recruited n = 1,002 twins and unrelated healthy adults in the United Kingdom to the PREDICT 1 study and assessed postprandial metabolic responses in a clinical setting and at home. We observed large inter-individual variability (as measured by the population coefficient of
The objective of this paper is to outline and discuss the key elements of an EU industrial development policy consistent with the Paris Agreement. We also assess the current EU Industrial Strategy proposal against these elements. The “well below 2 °C” target sets a clear limit for future global greenhouse gas emissions and thus strict boundaries for the development of future material demand, indus
This article addresses forward motion control for trajectory tracking and mobile formation coordination for a group of nonholonomic vehicles on SE(2). First, by constructing an intermediate attitude variable which involves vehicles' position information and desired attitude, the translational and rotational control inputs are designed in two stages to solve the trajectory tracking problem. Second,
III-nitrides are considered the material of choice for light-emitting diodes (LEDs) and lasers in the visible to ultraviolet spectral range. The development is hampered by lattice and thermal mismatch between the nitride layers and the growth substrate leading to high dislocation densities. In order to overcome the issue, efforts have gone into selected area growth of nanowires (NWs), using their
In animals, dihydroorotate dehydrogenase (DHODH) is a mitochondrial protein that carries out the fourth step in de novo pyrimidine biosynthesis. Because this is the only enzyme of this pathway that is localized to mitochondria and because the enzyme is cytosolic in some bacteria and fungi, we carried out studies to understand the mode of targeting of animal DHODH and its submitochondrial localizat
Different methods of trapping radioactive xenon are reviewed. Trapping by adsorption on activated charcoal has the advantage of being simple and cheap and also makes it possible to recycle the xenon. An activated charcoal trapping system is described which can extract 133Xe from 100l of expired air in 10 min from patients undergoing diagnostic pulmonary or circulation studies. Details of the const
