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Deficiencies of C2 and other components of the classical pathway of complement are associated with increased risk of infections with encapsulated bacteria, such as Haemophilus (H.) influenzae. Defense against H. influenzae is dependent on specific antibodies and complement, which mediate serum bactericidal activity (SBA) and opsonization. Due to lack of normal classical and lectin complement pathw
Organizations grow and excel with knowledge sharing; on the other hand, knowledge hiding is a negative behavior that impedes innovation, growth, problem solving, and timely correct decision making in organizations. It becomes more critical in the case of teaching hospitals, where, besides patient care, medical students are taught and trained. We assume that negative emotions lead employees to hide
This paper reports on a case study of a quadrilingual child, Stefan, born and raised in Sweden and exposed to four languages before his first birthday: English, French, Russian and Swedish. We examine his vocabularies in these languages by the Cross-Linguistic Lexical Tasks (Haman, Łuniewska, & Pomiechowska, 2015), designed to measure vocabulary in monolingual and multilingual children. Stefan
The aim of this theoretical paper is to critically reflect on the ethical and methodological issues that arose during a study that observed nurses’ care-giving in an intensive care unit setting. The authors critically discuss the methodological and ethical issues as well as the practical realities that were encountered when evaluating a complex intervention using unstructured qualitative observati
Although remarkable progress has been achieved in reducing hunger and poverty and improving people’s health in the past couple of decades, humanity still faces considerable socio-economic and sustainability challenges. Ensuring sustainable access to safe and sufficient water, improved sanitation facilities, clean energy sources and healthy food is a necessary requirement for ending hunger and pove
Penetration of the viral genome into a host cell nucleus is critical for initiation of viral replication for most DNA viruses and a few RNA viruses. For herpesviruses, viral DNA ejection into a nucleus occurs when the capsid docks at the nuclear pore complex (NPC) basket with the correct orientation of the unique capsid portal vertex. It has been shown that capsid vertex-specific component (CVSC)
In 1899, the British colonialist Cecil Rhodes went to Berlin to negotiate about his fantastical ‘Cape-to-Cairo’ telegraph and railway scheme with his former nemesis, the German emperor Wilhelm II. Why did this initiative of Rhodes, who was held responsible for the disastrous Jameson Raid and no longer occupied any official position, receive so much coverage and legitimacy in the international pres
Objective: Blindness and low vision have severe effects on individuals' quality of life and socioeconomic cost; a main contributor of which is a prevalent and acutely decreased mobility level. To alleviate this, numerous technological solutions have been proposed in the last 70 years; however, none has become widespread. Method: In this paper, we introduce the vision-to-audio, super-scale sensory
The barrier function of the skin mainly relies on its outermost layer, the stratum corneum (SC), which is a lipid-protein composite biomaterial. In addition, SC contains a mixture of small polar compounds, the natural moisturizing factor (NMF). Most of the NMF components are solid at ambient relative humidities (RHs). We herein raise the question of what the effects of adding a mixture of chemical
Domestic mallards (Anas platyrhynchos domesticus) are traditionally used as a model to investigate infection dynamics and immune responses to low pathogenic avian influenza viruses (LPAIVs) in free-living mallards. However, it is unclear whether the immune response of domestic birds reflects the response of their free-living counterparts naturally exposed to these viruses. We investigated the exte
Research on younger patients with hip fractures is limited. This study adds knowledge on patient and injury characteristics, and DXA was investigated at the time of the fracture. Risk factors for osteoporosis and fractures were numerous among young patients, and osteoporosis was markedly more prevalent than in the general population.INTRODUCTION: Knowledge on younger patients with hip fractures is
Purpose: Long-term follow-up (LTFU) care is essential to optimise health outcomes in childhood cancer survivors (CCS). We aimed to assess the impact of the COVID-19 pandemic on LTFU services and providers. Methods: A COVID-19 working group within the International Late Effects of Childhood Cancer Guideline Harmonization Group (IGHG) distributed a questionnaire to LTFU service providers in 37 count
PURPOSE: To report practice patterns of corneal transplantation in Europe. SETTING: Corneal clinics in 10 European member states (MS), the United Kingdom, and Switzerland. DESIGN: Multinational registry study. METHODS: Corneal transplant procedures registered in the European Cornea and Cell Transplantation Registry were identified. Preoperative donor and recipient characteristics, indication and r
On the Internet, many commentary styles take place on various forums, and abuse is not uncommon. We investigated the personality traits related to individuals’ behaviors on Internet forum posting. The Dark Short Tetrad (SD4) were used to predict (N = 212) three types of commentary styles: Trolling (malicious posting), Lurking (reading/not posting) and Posting (reading/posting). The results showed
ObjectiveThis paper examines a previously neglected phenomenon in doctor-patient interaction studies, i.e. the achievement of mutual disengagement—a specific state of coordination, in which participants suspend reciprocal gaze and turn into separate axes of involvement. In the specialized setting of the oncology visit, which we consider in this study, mutual disengagement is linked to important ta
This paper assesses the interrelation between economic inequality and social mobility in the long run. We use the unique Barcelona Historical Marriage Database for 1545-1880, accounting for more than 60,000 parents-children links. Analytically, we combine individuals' socioeconomic relative position for decomposing inequality individually in the overall population and by subgroups (social class) w
For magnetic resonance imaging (MRI) of non-traumatic brachial plexus (BP) lesions, sequences with contrast injection should be considered in the differentiation between tumors, infection, postoperative conditions, and post-radiation changes. The most common non-traumatic inflammatory BP neuropathy is radiation neuropathy. T2-weighted images may help to distinguish neoplastic infiltration showing
To assess the role of feral oilseed rape (OSR) plants as resources for pollinators and avenues for gene flow, we compared occurrence of feral populations in standardized agricultural landscapes, using a landscape ecological approach. The occurrence of feral and volunteer populations was investigated in relation to differences in road length and width, number of OSR fields, and landscape scale. The
The chapter analyses three cases that all began as rape reports, but where seemingly greater dangers, such as “the HIV virus” and “the Internet”, were identified and prioritised over rape in the news. Consequently, the news media figures the HIV Man, Alexandra Man and Hotboy were introduced. Based on the overarching question “How is rape portrayed in the news media?” the objective is to analyse ho
Background and purpose - Knowing how to interpret values obtained with patient reported outcome measures (PROMs) is essential. We estimated the substantial clinical benefit (SCB) and patient acceptable symptom state (PASS) for Forgotten Joint Score 12 (FJS) and explored differences depending on methods used for the estimates. Patients and methods - The study was based on 195 knee arthroplasties (K
